Imperial College London
Alternate

ProfessorElioRiboli

Faculty of Medicine, School of Public Health

Chair in Cancer Epidemiology and Prevention
 
 
 
//

Contact

 

e.riboli Website CV

 
 
//

Assistant

 

Ms Julieta Dourado +44 (0)20 7594 3426

 
//

Location

 

152Medical SchoolSt Mary's Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Watts:2017:10.1371/journal.pone.0187741,
author = {Watts, EL and Appleby, PN and Albanese, D and Black, A and Chan, JM and Chen, C and Cirillo, PM and Cohn, BA and Cook, MB and Donovan, JL and Ferrucci, L and Garland, CF and Giles, GG and Goodman, PJ and Habel, LA and Haiman, CA and Holly, JMP and Hoover, RN and Kaaks, R and Knekt, P and Kolonel, LN and Kubo, T and Le, Marchand L and Luostarinen, T and Maclnnis, RJ and Maenpaa, HO and Mannisto, S and Metter, EJ and Milne, RL and Nomura, AMY and Oliver, SE and Parsons, JK and Peeters, PH and Platz, EA and Riboli, E and Ricceri, F and Rinaldi, S and Rissanen, H and Sawada, N and Schaefer, CA and Schenk, JM and Stanczyk, FZ and Stampfer, M and Stattin, P and Stenman, U-H and Tjonneland, A and Trichopoulou, A and Thompson, IM and Tsugane, S and Vatten, L and Whittemore, AS and Ziegler, RG and Allen, NE and Key, TJ and Travis, RC},
doi = {10.1371/journal.pone.0187741},
journal = {PLoS ONE},
title = {Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men},
url = {http://dx.doi.org/10.1371/journal.pone.0187741},
volume = {12},
year = {2017}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - IntroductionSex hormones have been implicated in the etiology of a number of diseases. To better understand disease etiology and the mechanisms of disease-risk factor associations, this analysis aimed to investigate the associations of anthropometric, sociodemographic and behavioural factors with a range of circulating sex hormones and sex hormone-binding globulin.MethodsStatistical analyses of individual participant data from 12,330 male controls aged 25–85 years from 25 studies involved in the Endogenous Hormones Nutritional Biomarkers and Prostate Cancer Collaborative Group. Analysis of variance was used to estimate geometric means adjusted for study and relevant covariates.ResultsOlder age was associated with higher concentrations of sex hormone-binding globulin and dihydrotestosterone and lower concentrations of dehydroepiandrosterone sulfate, free testosterone, androstenedione, androstanediol glucuronide and free estradiol. Higher body mass index was associated with higher concentrations of free estradiol, androstanediol glucuronide, estradiol and estrone and lower concentrations of dihydrotestosterone, testosterone, sex hormone-binding globulin, free testosterone, androstenedione and dehydroepiandrosterone sulfate. Taller height was associated with lower concentrations of androstenedione, testosterone, free testosterone and sex hormone-binding globulin and higher concentrations of androstanediol glucuronide. Current smoking was associated with higher concentrations of androstenedione, sex hormone-binding globulin and testosterone. Alcohol consumption was associated with higher concentrations of dehydroepiandrosterone sulfate, androstenedione and androstanediol glucuronide. East Asians had lower concentrations of androstanediol glucuronide and African Americans had higher concentrations of estrogens. Education and marital status were modestly associated with a small number of hormones.ConclusionCirculating sex hormones in men are strongly associated with
AU  - Watts,EL
AU  - Appleby,PN
AU  - Albanese,D
AU  - Black,A
AU  - Chan,JM
AU  - Chen,C
AU  - Cirillo,PM
AU  - Cohn,BA
AU  - Cook,MB
AU  - Donovan,JL
AU  - Ferrucci,L
AU  - Garland,CF
AU  - Giles,GG
AU  - Goodman,PJ
AU  - Habel,LA
AU  - Haiman,CA
AU  - Holly,JMP
AU  - Hoover,RN
AU  - Kaaks,R
AU  - Knekt,P
AU  - Kolonel,LN
AU  - Kubo,T
AU  - Le,Marchand L
AU  - Luostarinen,T
AU  - Maclnnis,RJ
AU  - Maenpaa,HO
AU  - Mannisto,S
AU  - Metter,EJ
AU  - Milne,RL
AU  - Nomura,AMY
AU  - Oliver,SE
AU  - Parsons,JK
AU  - Peeters,PH
AU  - Platz,EA
AU  - Riboli,E
AU  - Ricceri,F
AU  - Rinaldi,S
AU  - Rissanen,H
AU  - Sawada,N
AU  - Schaefer,CA
AU  - Schenk,JM
AU  - Stanczyk,FZ
AU  - Stampfer,M
AU  - Stattin,P
AU  - Stenman,U-H
AU  - Tjonneland,A
AU  - Trichopoulou,A
AU  - Thompson,IM
AU  - Tsugane,S
AU  - Vatten,L
AU  - Whittemore,AS
AU  - Ziegler,RG
AU  - Allen,NE
AU  - Key,TJ
AU  - Travis,RC
DO  - 10.1371/journal.pone.0187741
PY  - 2017///
SN  - 1932-6203
TI  - Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men
T2  - PLoS ONE
UR  - http://dx.doi.org/10.1371/journal.pone.0187741
UR  - http://hdl.handle.net/10044/1/56402
VL  - 12
ER  -
Download