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@article{Tsocheva:2023:10.1186/s12887-023-04384-5,
author = {Tsocheva, I and Scales, J and Dove, R and Chavda, J and Kalsi, H and Wood, HE and Colligan, G and Cross, L and Newby, C and Hall, A and Keating, M and Sartori, L and Moon, J and Thomson, A and Tomini, F and Murray, A and Hamad, W and Tijm, S and Hirst, A and Vincent, BP and Kotala, P and Balkwill, F and Mihaylova, B and Grigg, J and Quint, JK and Fletcher, M and Mon-Williams, M and Wright, J and van, Sluijs E and Beevers, S and Randhawa, G and Eldridge, S and Sheikh, A and Gauderman, W and Kelly, F and Mudway, IS and Griffiths, CJ},
doi = {10.1186/s12887-023-04384-5},
journal = {BMC Pediatrics},
title = {Investigating the impact of London's ultra low emission zone on children's health: children's health in London and Luton (CHILL) protocol for a prospective parallel cohort study},
url = {http://dx.doi.org/10.1186/s12887-023-04384-5},
volume = {23},
year = {2023}
}

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TY  - JOUR
AB  - BACKGROUND: Air pollution harms health across the life course. Children are at particular risk of adverse effects during development, which may impact on health in later life. Interventions that improve air quality are urgently needed both to improve public health now, and prevent longer-term increased vulnerability to chronic disease. Low Emission Zones are a public health policy intervention aimed at reducing traffic-derived contributions to urban air pollution, but evidence that they deliver health benefits is lacking. We describe a natural experiment study (CHILL: Children's Health in London and Luton) to evaluate the impacts of the introduction of London's Ultra Low Emission Zone (ULEZ) on children's health. METHODS: CHILL is a prospective two-arm parallel longitudinal cohort study recruiting children at age 6-9 years from primary schools in Central London (the focus of the first phase of the ULEZ) and Luton (a comparator site), with the primary outcome being the impact of changes in annual air pollutant exposures (nitrogen oxides [NOx], nitrogen dioxide [NO2], particulate matter with a diameter of less than 2.5micrograms [PM2.5], and less than 10 micrograms [PM10]) across the two sites on lung function growth, measured as post-bronchodilator forced expiratory volume in one second (FEV1) over five years. Secondary outcomes include physical activity, cognitive development, mental health, quality of life, health inequalities, and a range of respiratory and health economic data. DISCUSSION: CHILL's prospective parallel cohort design will enable robust conclusions to be drawn on the effectiveness of the ULEZ at improving air quality and delivering improvements in children's respiratory health. With increasing proportions of the world's population now living in large urban areas exceeding World Health Organisation air pollution limit guidelines, our study findings will have important implications for the design and implementation of Low Emission and Clean Air Zones
AU  - Tsocheva,I
AU  - Scales,J
AU  - Dove,R
AU  - Chavda,J
AU  - Kalsi,H
AU  - Wood,HE
AU  - Colligan,G
AU  - Cross,L
AU  - Newby,C
AU  - Hall,A
AU  - Keating,M
AU  - Sartori,L
AU  - Moon,J
AU  - Thomson,A
AU  - Tomini,F
AU  - Murray,A
AU  - Hamad,W
AU  - Tijm,S
AU  - Hirst,A
AU  - Vincent,BP
AU  - Kotala,P
AU  - Balkwill,F
AU  - Mihaylova,B
AU  - Grigg,J
AU  - Quint,JK
AU  - Fletcher,M
AU  - Mon-Williams,M
AU  - Wright,J
AU  - van,Sluijs E
AU  - Beevers,S
AU  - Randhawa,G
AU  - Eldridge,S
AU  - Sheikh,A
AU  - Gauderman,W
AU  - Kelly,F
AU  - Mudway,IS
AU  - Griffiths,CJ
DO  - 10.1186/s12887-023-04384-5
PY  - 2023///
SN  - 1471-2431
TI  - Investigating the impact of London's ultra low emission zone on children's health: children's health in London and Luton (CHILL) protocol for a prospective parallel cohort study
T2  - BMC Pediatrics
UR  - http://dx.doi.org/10.1186/s12887-023-04384-5
UR  - https://www.ncbi.nlm.nih.gov/pubmed/37925402
UR  - http://hdl.handle.net/10044/1/109936
VL  - 23
ER  -

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