Imperial College London
Alternate

Jeff Imai-Eaton

Faculty of Medicine, School of Public Health

Senior Research Fellow
 
 
 
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Contact

 

jeffrey.eaton

 
 
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Location

 

UG7Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Howes:2023:10.1371/journal.pgph.0001731,
author = {Howes, A and Risher, K and Nguyen, VK and Stevens, O and Jia, K and Wolock, T and Esra, R and Zembe, L and Wanyeki, I and Mahy, M and Benedikt, C and Flaxman, S and Eaton, J},
doi = {10.1371/journal.pgph.0001731},
journal = {PLOS Global Public Health},
pages = {1--14},
title = {Spatio-temporal estimates of HIV risk group proportions for adolescent girls and young women across 13 priority countries in sub-Saharan Africa},
url = {http://dx.doi.org/10.1371/journal.pgph.0001731},
volume = {3},
year = {2023}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The Global AIDS Strategy 2021-2026 identifies adolescent girls and young women (AGYW) as a priority population for HIV prevention, and recommends differentiating intervention portfolios geographically based on local HIV incidence and individual risk behaviours. We estimated prevalence of HIV risk behaviours and associated HIV incidence at health district level among AGYW living in 13 countries in sub-Saharan Africa. We analysed 46 geospatially-referenced national household surveys conducted between 1999-2018 across 13 high HIV burden countries in sub-Saharan Africa. Female survey respondents aged 15-29 years were classified into four risk groups (not sexually active, cohabiting, non-regular or multiple partner[s] and female sex workers [FSW]) based on reported sexual behaviour. We used a Bayesian spatio-temporal multinomial regression model to estimate the proportion of AGYW in each risk group stratified by district, year, and five-year age group. Using subnational estimates of HIV prevalence and incidence produced by countries with support from UNAIDS, we estimated new HIV infections in each risk group by district and age group. We then assessed the efficiency of prioritising interventions according to risk group. Data consisted of 274,970 female survey respondents aged 15-29. Among women aged 20-29, cohabiting (63.1%) was more common in eastern Africa than non-regular or multiple partner(s) (21.3%), while in southern countries non-regular or multiple partner(s) (58.9%) were more common than cohabiting (23.4%). Risk group proportions varied substantially across age groups (65.9% of total variation explained), countries (20.9%), and between districts within each country (11.3%), but changed little over time (0.9%). Prioritisation based on behavioural risk, in combination with location- and age-based prioritisation, reduced the proportion of population required to be reached in order to find half of all expected new infections from 19.4% to 10.6%. FSW were 1.3% of th
AU  - Howes,A
AU  - Risher,K
AU  - Nguyen,VK
AU  - Stevens,O
AU  - Jia,K
AU  - Wolock,T
AU  - Esra,R
AU  - Zembe,L
AU  - Wanyeki,I
AU  - Mahy,M
AU  - Benedikt,C
AU  - Flaxman,S
AU  - Eaton,J
DO  - 10.1371/journal.pgph.0001731
EP  - 14
PY  - 2023///
SN  - 2767-3375
SP  - 1
TI  - Spatio-temporal estimates of HIV risk group proportions for adolescent girls and young women across 13 priority countries in sub-Saharan Africa
T2  - PLOS Global Public Health
UR  - http://dx.doi.org/10.1371/journal.pgph.0001731
UR  - https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0001731
UR  - http://hdl.handle.net/10044/1/103853
VL  - 3
ER  -
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