We are interested in how the molecular machinery of the cell assembles, functions, and evolves. To tackle this problem we use electron cryo-tomography, a technique that enables us to visualize this machinery inside living cells -- to resolutions capable of discerning individual proteins.
I am co-director of the Department of Life Science's MRes in Structural Molecular Biology. Please click here for more details.
Please visit our lab website!
et al., Propulsive nanomachines: the convergent evolution of archaella, flagella, and cilia, Fems Microbiology Reviews, ISSN:0168-6445
et al., 2020, Diversification of campylobacter jejuni flagellar C-Ring composition impacts its structure and function in motility, flagellar assembly, and cellular processes., Mbio, Vol:11, ISSN:2150-7511, Pages:1-21
et al., 2020, The structure of the periplasmic FlaG-FlaF complex and its essential role for archaellar swimming motility, Nature Microbiology, Vol:5, ISSN:2058-5276, Pages:216-225
Beeby M, 2019, Evolution of a family of molecular Rube Goldberg contraptions, Plos Biology, Vol:17, ISSN:1544-9173
et al., 2019, γ-proteobacteria eject their polar flagella under nutrient depletion, retaining flagellar motor relic structures, Plos Biology, Vol:17, ISSN:1544-9173