We are interested in how the molecular machinery of the cell assembles, functions, and evolves. To tackle this problem we use electron cryo-tomography, a technique that enables us to visualize this machinery inside living cells -- to resolutions capable of discerning individual proteins.
I am co-director of the Department of Life Science's MRes in Structural Molecular Biology. Please click here for more details.
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et al., 2020, Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis., Elife, Vol:9
et al., 2020, CryoEM of bacterial secretion systems: a primer for microbiologists., Mol Microbiol
et al., 2020, Adenita: interactive 3D modelling and visualization of DNA nanostructures, Nucleic Acids Research, Vol:48, ISSN:0305-1048, Pages:8269-8275
et al., 2020, An ATP-dependent partner switch links flagellar C-ring assembly with gene expression, Proceedings of the National Academy of Sciences of the United States of America, Vol:117, ISSN:0027-8424, Pages:20826-20835
et al., 2020, Trichinella spiralis secretes abundant unencapsulated small RNAs with potential effects on host gene expression, International Journal for Parasitology, Vol:50, ISSN:0020-7519, Pages:697-705