Imperial College London


Faculty of Natural SciencesDepartment of Life Sciences

Senior Lecturer



+44 (0)20 7594 5251m.beeby Website




502Sir Ernst Chain BuildingSouth Kensington Campus





We are interested in how the molecular machinery of the cell assembles, functions, and evolves. To tackle this problem we use electron cryo-tomography, a technique that enables us to visualize this machinery inside living cells -- to resolutions capable of discerning individual proteins.

I am co-director of the Department of Life Science's MRes in Structural Molecular Biology. Please click here for more details.

Please visit our lab website!




Matthews-Palmer T, Gonzalez-Rodriguez N, Calcraft T, et al., 2021, Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism, Journal of Structural Biology, Vol:213, ISSN:1047-8477

Ferreira J, coleman I, Addison M, et al., 2021, The 'jack-of-all-trades' flagellum from Salmonella and E. coli was horizontally acquired from an ancestral beta-proteobacterium, Frontiers in Microbiology, Vol:12, ISSN:1664-302X

Sivabalasarma S, Wetzel H, Nussbaum P, et al., 2021, Analysis of Cell-Cell Bridges in Haloferax volcanii Using Electron Cryo-Tomography Reveal a Continuous Cytoplasm and S-Layer, Frontiers in Microbiology, Vol:11, ISSN:1664-302X

Umrekar TR, Cohen E, Drobnic T, et al., 2020, CryoEM of bacterial secretion systems: A primer for microbiologists, Molecular Microbiology, Vol:115, ISSN:0950-382X, Pages:366-382

Alvira S, Watkins DW, Troman L, et al., 2020, Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis, Elife, Vol:9, ISSN:2050-084X

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