Imperial College London

ProfessorPhilipMolyneaux

Faculty of MedicineNational Heart & Lung Institute

Professor of Interstitial Lung Disease
 
 
 
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Contact

 

p.molyneaux

 
 
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Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Furusawa:2022:10.1136/thoraxjnl-2021-217693,
author = {Furusawa, H and Peljto, AL and Walts, AD and Cardwell, J and Molyneaux, PL and Lee, JS and Fernández, Pérez ER and Wolters, PJ and Yang, IV and Schwartz, DA},
doi = {10.1136/thoraxjnl-2021-217693},
journal = {Thorax},
title = {Common idiopathic pulmonary fibrosis risk variants are associated with hypersensitivity pneumonitis},
url = {http://dx.doi.org/10.1136/thoraxjnl-2021-217693},
volume = {77},
year = {2022}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - A subset of patients with hypersensitivity pneumonitis (HP) develop lung fibrosis that is clinically similar to idiopathic pulmonary fibrosis (IPF). To address the aetiological determinants of fibrotic HP, we investigated whether the common IPF genetic risk variants were also relevant in study subjects with fibrotic HP. Our findings indicate that common genetic variants in TERC, DSP, MUC5B and IVD were significantly associated with fibrotic HP. These findings provide support for a shared etiology and pathogenesis between fibrotic HP and IPF.
AU - Furusawa,H
AU - Peljto,AL
AU - Walts,AD
AU - Cardwell,J
AU - Molyneaux,PL
AU - Lee,JS
AU - Fernández,Pérez ER
AU - Wolters,PJ
AU - Yang,IV
AU - Schwartz,DA
DO - 10.1136/thoraxjnl-2021-217693
PY - 2022///
SN - 0040-6376
TI - Common idiopathic pulmonary fibrosis risk variants are associated with hypersensitivity pneumonitis
T2 - Thorax
UR - http://dx.doi.org/10.1136/thoraxjnl-2021-217693
UR - https://www.ncbi.nlm.nih.gov/pubmed/34996848
UR - https://thorax.bmj.com/content/77/5/508.info
UR - http://hdl.handle.net/10044/1/93566
VL - 77
ER -