Imperial College London
Portrait Picture

Dr Ricardo Petraco

Faculty of Medicine, National Heart & Lung Institute

Honorary Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 3386r.petraco

 
 
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Location

 

Block B Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Ng:2016:10.1016/j.ijcard.2016.06.097,
author = {Ng, J and Foin, N and Ang, HY and Fam, JM and Sen, S and Nijjer, S and Petraco, R and Di, Mario C and Davies, J and Wong, P},
doi = {10.1016/j.ijcard.2016.06.097},
journal = {International Journal of Cardiology},
pages = {171--179},
title = {Over-expansion capacity and stent design model: an update with contemporary DES platforms},
url = {http://dx.doi.org/10.1016/j.ijcard.2016.06.097},
volume = {221},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Previously, we examined the difference in stent designs across different sizes for six widely used Drug Eluting Stents (DESs). Although stent post-dilatation to larger diameter is commonly done, typically in the setting of long tapering segment or left-main PCI, there is an increasing recognition that information with regard to the different stent model designs has a critical impact on overexpansion results. This study aims to provide an update on stent model designs for contemporary DES platforms as well as test overexpansion results under with oversized post-dilatation. METHODS AND RESULTS: We studied 6 different contemporary commercially available DES platforms: Synergy, Xience Xpedition, Ultimaster, Orsiro, Resolute Onyx and Biomatrix Alpha. We investigated for each platform the difference in stent designs across different sizes and results obtained after post-expansion with larger balloon sizes. The stents were deployed at nominal diameter and subsequently over expanded using increasingly large post dilatation balloon sizes (4.0, 5.0 and 6.0mm at 14ATM). Light microscopy was used to measure the changes in stent geometry and lumen diameter after over-expansion. For each respective DES platform, the MLD observed after overexpansion of the largest stent size available with a 6.0mm balloon was 5.7mm for Synergy, 5.6mm for Xience, 5.2mm for Orsiro, 5.8mm for Ultimaster, 5.5mm for 4mm Onyx (5.9mm for the 5mm XL size) and 5.8mm for BioMatrix Chroma. CONCLUSION: This update presents valuable novel insights that may be helpful for careful selection of stent size for contemporary DES based on model designs. Such information is especially critical in left main bifurcation stenosis treatment where overexpansion to larger oversized diameter may be required to ensure full stent apposition.
AU  - Ng,J
AU  - Foin,N
AU  - Ang,HY
AU  - Fam,JM
AU  - Sen,S
AU  - Nijjer,S
AU  - Petraco,R
AU  - Di,Mario C
AU  - Davies,J
AU  - Wong,P
DO  - 10.1016/j.ijcard.2016.06.097
EP  - 179
PY  - 2016///
SN  - 1874-1754
SP  - 171
TI  - Over-expansion capacity and stent design model: an update with contemporary DES platforms
T2  - International Journal of Cardiology
UR  - http://dx.doi.org/10.1016/j.ijcard.2016.06.097
UR  - http://hdl.handle.net/10044/1/37040
VL  - 221
ER  -
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