Imperial College London
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ProfessorRoxySenior

Faculty of Medicine, National Heart & Lung Institute

Professor of Clinical Cardiology
 
 
 
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Contact

 

+44 (0)20 7351 8635r.senior

 
 
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Location

 

Chelsea WingRoyal Brompton Campus

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Summary

 

Publications

Citation

BibTex format

@article{Kataoka:2016:10.1111/echo.13222,
author = {Kataoka, A and Scherrer-Crosbie, M and Senior, R and Garceau, P and Valbuena, S and elutkien, J and Hastings, JL and Cheema, AN and Lara, A and Srbinovska-Kostovska, E and Hessian, R and Poggio, D and Goldweit, R and Saric, M and Dajani, KA and Kohn, JA and Shaw, LJ and Reynolds, HR and Picard, MH},
doi = {10.1111/echo.13222},
journal = {Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques},
title = {Transient Ischemic Dilatation during Stress Echocardiography: An Additional Marker of Significant Myocardial Ischemia.},
url = {http://dx.doi.org/10.1111/echo.13222},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - AIM: Left ventricular (LV) transient ischemic dilatation (TID) is not clear how it relates to inducible myocardial ischemia during stress echocardiography (SE). METHODS AND RESULTS: Eighty-eight SEs were examined from the site certification phase of the ISCHEMIA Trial. LV end-diastolic volume (EDV) and end-systolic volume (ESV) were measured at rest and peak stages and the percent change calculated. Moderate or greater ischemia was defined as ≥3 segments with stress-induced severe hypokinesis or akinesis. Optimum cut points in stress-induced percent EDV and ESV change that identified moderate or greater myocardial ischemia were analyzed. Analysis from percentage distribution identified a > 13% LV volume increase in EDV or a > 9% LV volume increase in ESV as the optimum cutoff points for moderate or greater ischemia. Using these definitions for TID, there were 27 (31%) with TIDESV and 12 (14%) with TIDEDV . By logistic regression analysis and receiver operating characteristic curves, the percent change in ESV had a stronger association with moderate or greater myocardial ischemia than that of EDV change. Compared to those without TIDESV , cases with TIDESV had larger extent of inducible wall-motion abnormalities, lower peak stress LVEF, and higher likelihood of moderate or grater ischemia. For moderate or greater myocardial ischemia detection, TIDESV had a sensitivity of 46%, specificity of 83%, positive predictive value of 70%, and negative predictive value of 64%. CONCLUSION: Transient ischemic dilatation by SE is a marker of extensive myocardial ischemia and can be used as an additional marker of higher risk.
AU  - Kataoka,A
AU  - Scherrer-Crosbie,M
AU  - Senior,R
AU  - Garceau,P
AU  - Valbuena,S
AU  - elutkien,J
AU  - Hastings,JL
AU  - Cheema,AN
AU  - Lara,A
AU  - Srbinovska-Kostovska,E
AU  - Hessian,R
AU  - Poggio,D
AU  - Goldweit,R
AU  - Saric,M
AU  - Dajani,KA
AU  - Kohn,JA
AU  - Shaw,LJ
AU  - Reynolds,HR
AU  - Picard,MH
DO  - 10.1111/echo.13222
PY  - 2016///
SN  - 1540-8175
TI  - Transient Ischemic Dilatation during Stress Echocardiography: An Additional Marker of Significant Myocardial Ischemia.
T2  - Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques
UR  - http://dx.doi.org/10.1111/echo.13222
ER  -
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