Publications
780 results found
Athanasiou T, Ashrafian H, Glenville B, et al., 2004, Coronary artery bypass with the use of a magnetic distal anastomotic device: Surgical technique and preliminary experience, HEART SURGERY FORUM, Vol: 7, Pages: E344-E347, ISSN: 1098-3511
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- Citations: 11
Athanasiou T, Aziz T, Aziz O, et al., 2004, Apical suction device facilitating off-pump bypass for recurrent coarctation: Case report, HEART SURGERY FORUM, Vol: 7, Pages: E177-E178, ISSN: 1098-3511
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- Citations: 2
Al-Ruzzeh S, Athanasiou T, George S, et al., 2004, Methodological approach in adopting off-pump coronary artery bypass surgery in a British cardiothoracic unit: Harefield experience, PERFUSION-UK, Vol: 19, Pages: S61-S66, ISSN: 0267-6591
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- Citations: 6
Purkayastha S, Aziz O, Athanasiou T, et al., 2004, Does laparoscopic surgery offer adequate clearance for rectal cancer? – a discussion., International Journal of Surgery, Vol: 2
Casula R, Athanasiou T, 2004, Totally endoscopic coronary artery bypass on the beating heart in Jehovah's witness and HIV patients: Case report, HEART SURGERY FORUM, Vol: 7, Pages: E174-E176, ISSN: 1098-3511
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- Citations: 5
Ashrafian H, Kumar P, Athanasiou T, et al., 2003, Minimally invasive off-pump pulmonary embolectomy., Cardiovasc Surg, Vol: 11, Pages: 471-473, ISSN: 0967-2109
We report the case of a 35-year-old female with acute massive right pulmonary embolism, successfully treated by a minimally invasive off-pump pulmonary embolectomy-the first case in the literature implemented via the J-ministernotomy.
Athanasiou T, Aziz O, Skapinakis P, et al., 2003, Leg wound infection after coronary artery bypass grafting: A meta-analysis comparing minimally invasive versus conventional vein harvesting, ANNALS OF THORACIC SURGERY, Vol: 76, Pages: 2141-2146, ISSN: 0003-4975
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- Citations: 83
Athanasiou A, Perunovic B, Quilty RD, et al., 2003, Expression of mos in ependymal gliomas, AMERICAN JOURNAL OF CLINICAL PATHOLOGY, Vol: 120, Pages: 699-705, ISSN: 0002-9173
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- Citations: 8
Casula RP, Kumar P, Ashrafian H, et al., 2003, Evolving techniques for endoscopic radial artery harvesting., Cardiovasc Surg, Vol: 11, Pages: 425-427, ISSN: 0967-2109
The role of radial artery as an arterial conduit for myocardial revascularisation is well established. Minimally invasive approaches for the harvesting of conduits are desirable for clinical and cosmetic reasons. We report our experience with two techniques of endoscopic radial artery harvesting. The techniques are illustrated and their relative advantages discussed.
Mangoush O, Nakamura K, Al-Ruzzeh S, et al., 2003, Effect of ascorbic acid on endothelium-dependent vasodilatation of human arterial conduits for coronary artery bypass grafting., Eur J Cardiothorac Surg, Vol: 24, Pages: 541-546, ISSN: 1010-7940
OBJECTIVE: Techniques aimed at improving the performance of arterial conduits will maximize the clinical benefit achievable with coronary artery bypass surgery. Controlling oxidant stress could be a strategy for preventing early graft deterioration. We tested the effect of a free radical scavenger, ascorbic acid (vitamin C), on preserving the endothelium-dependent vasodilatation function in vitro of radial artery and internal thoracic artery. We also tested its effect on the amount of reactive oxygen species (ROS) generated by each graft. METHODS: Radial artery (RA, n=25) and internal thoracic (ITA, n=19) segments were obtained from coronary artery bypass grafting patients. Each segment was divided into 3-4 mm vascular rings and incubated with or without ascorbic acid (10(-3) mol/l) for 1 h or 72 h. Using the organ bath technique, the endothelium-dependent vasodilatation function was tested in vitro by the addition of cumulative concentrations of acetylcholine (10(-9)-10(-5) mol/l) following vasocontraction by endothelin-1 (3 x 10(-8) mol/l). ROS were measured by using chemiluminescence technique at 1-h and after 72 h incubation with or without ascorbic acid. RESULTS: There were no differences in the vasodilatation function between control and ascorbic acid group of both arteries in the 1-hour incubation experiment. However, in the 72 h incubation experiment, ascorbic acid preserved the endothelium-dependent vasodilatation function of RA compared with control group (35.8+/-2.2% vs. 25.9+/-2.1%; P=0.005), but not ITA (39+/-3.5% vs. 40.5+/-9.3%; P=0.438). After 72 h incubation, RA generated significantly more free radicals compared with 1 h (133.7+/-151.5 vs. 16.8+/-16.8 cps/mg x 100; P=0.01); however, AA has no statistically significant effect on decreasing the amount of free radicals generated by both arteries. CONCLUSIONS: In RA, ascorbic acid is able to preserve the endothelium-dependent vasodilatation function after 72 h incubation, but not after 1 h. However, th
Athanasiou T, Kumar P, Al-Ruzzeh S, et al., 2003, Expanded use of suction and stabilization devices in cardiothoracic surgery, ANNALS OF THORACIC SURGERY, Vol: 76, Pages: 1126-1130, ISSN: 0003-4975
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- Citations: 6
Casula RP, Velissaris TJ, Dar M, et al., 2003, Is early hospital discharge feasible following normothermic coronary artery surgery on the fibrillating heart?, J Cardiovasc Surg (Torino), Vol: 44, Pages: 583-589, ISSN: 0021-9509
AIM: Protocols for the earlier discharge of cardiac surgical patients are gaining popularity. We present our experience with an early hospital discharge policy following coronary artery bypass grafting (CABG) on the fibrillating heart. METHODS: Three-hundred and ninety-two consecutive patients who underwent elective CABG by a single surgeon were retrospectively reviewed. CABG was performed initially (1998-1999) in 191 patients with cardiopulmonary bypass (CPB) normothermia, intermittent aortic cross-clamping (AXC) and ventricular fibrillation and later (2001-2003) in 201 patients without CPB. Emphasis was given on short AXC and CPB times, early extubation, early mobilization and atrial fibrillation prophylaxis. Discharge criteria were as follows: walking on stairs unassisted, sinus rhythm for 24 hours, normal bowel function, apyrexia, family support at home. A 6-week follow-up clinic visit was arranged. Hospital re-admissions were carefully monitored. RESULTS: The mean (+/-SD) age of the patients was 62+/-9.6 years and the mean Parsonnet score was 6.7. The mean hospital stay was 6.1+/-2.5 days. Sixty-three (16%) and 171 (44%) patients were discharged by postoperative day 4 and 5, respectively. The following factors were independently associated with longer hospital stay: number of grafts performed (>3), requirement for postoperative inotropic support and social circumstances inadequate for early discharge. Twenty-three patients (5.8%) were re-admitted in the 6-week postoperative period. Shorter hospital stay was not associated with increased risk of re-admission. CONCLUSION: Early discharge after CABG with ventricular fibrillation is achievable, comparable to "fast-track techniques" without the use of CPB and is not associated with higher re-admission rates. We recommend the routine use of this protocol in all patients undergoing primary elective CABG.
Kumar P, Swift SJP, Athanasiou T, et al., 2003, CABG 15-years after left pneumonectomy: feasibility of off-pump approach., Cardiovasc Surg, Vol: 11, Pages: 305-307, ISSN: 0967-2109
We report the case of a 70-year-old man who underwent off-pump coronary artery bypass grafting 15-years after left pneumonectomy. He had significant two-vessel coronary artery disease. Comorbidities included poor ventricular function and impaired respiratory function. Operative risks in this clinical setting is increased. Our patient underwent off-pump CABG x 2. Thoracic epidural analgesia was also used to facilitate post-operative recovery. The patient was extubated an hour after the end of the procedure. The role of off-pump surgery in this high-risk population and the use of stabilizing devices in these extreme anatomical situations is discussed.
Al-Ruzzeh S, Athanasiou T, George S, et al., 2003, Is the use of cardiopulmonary bypass for multivessel coronary artery bypass surgery an independent predictor of operative mortality in patients with ischemic left ventricular dysfunction?, ANNALS OF THORACIC SURGERY, Vol: 76, Pages: 444-451, ISSN: 0003-4975
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- Citations: 28
Casula RP, Athanasiou T, Cherian A, et al., 2003, Totally endoscopic robotically enhanced coronary artery bypass on the beating heart., J R Soc Med, Vol: 96, Pages: 400-401, ISSN: 0141-0768
Athanasiou T, Al-Ruzzeh S, Del Stanbridge R, et al., 2003, Is the female gender an independent predictor of adverse outcome after off-pump coronary artery bypass grafting?, ANNALS OF THORACIC SURGERY, Vol: 75, Pages: 1153-1160, ISSN: 0003-4975
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- Citations: 29
Kumar P, Athanasiou T, Sarkar PK, 2003, Inhaled foreign bodies in children: diagnosis and treatment, HOSPITAL MEDICINE, Vol: 64, Pages: 218-222, ISSN: 1462-3935
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- Citations: 1
Charitou A, Athanasiou T, Morgan IS, et al., 2003, Use of Cough Lok can predispose to axillary artery thrombosis after a Robicsek procedure., Interact Cardiovasc Thorac Surg, Vol: 2, Pages: 68-69
OBJECTIVES: To present a rare complication of the use of Cough Lok following coronary artery surgery. METHODS: Case report. RESULTS: Report of axillary artery thrombosis following use of Cough Lok. CONCLUSIONS: Axillary artery thrombosis as a complication related to the use of the Cough Lok belt has not been previously reported. This rare complication was treated with endovascular thrombolysis. Staff awareness is the most important factor for its prevention.
Athanasiou T, Casula R, Glenville B, et al., 2003, A new method of grafting the circumflex through lateral MIDCAB with the use of the radial loop technique., Interact Cardiovasc Thorac Surg, Vol: 2, Pages: 97-98
We report a technique that allows total arterial revascularization of the circumflex territory without cardiopulmonary bypass through limited thoracotomy with the radial as a composite graft. The technique includes anastomosis of the distal end of the radial artery to its more proximal part after the division of the conduit from the brachial artery. In this way we create an adjustable loop that can be divided and used as bifurcated conduit in two coronary targets according to the needs of revascularization.
Al-Ruzzeh S, Nakamura K, Athanasiou T, et al., 2003, Does off-pump coronary artery bypass (OPCAB) surgery improve the outcome in high-risk patients?: a comparative study of 1398 high-risk patients, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 23, Pages: 50-55, ISSN: 1010-7940
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- Citations: 142
Athanasiou T, Casula R, Charitou A, et al., 2003, How I do it: a new method of myocardial revascularization with use of the radial loop technique., Heart Surg Forum, Vol: 6, Pages: E68-E69
We report a technique that allows total arterial myocardial revascularization of the left ventricle by the use of the radial artery as a composite graft. The technique includes anastomosis of the distal end of the radial artery to its more proximal part after division of the conduit from the brachial artery. In this way we create an adjustable loop that can be divided and used as a Y-fashioned conduit according to the needs of revascularization. The main advantages of this technique are that it saves time and facilitates complex arterial revascularization of the lateral and posterior parts of the left ventricle, especially during off-pump revascularization. At least 2 coronary targets can be revascularized with the radial artery in a flexible and safe manner. The radial artery also has important potential opportunities for multiple grafting through minimal-access incisions or endoscopic coronary artery bypass grafting when a critical Y anastomosis is needed inside the chest.
Gazouli M, Kokotas S, Zoumpourlis V, et al., 2002, The complement inhibitor CD59 and the lymphocyte function-associated antigen-3 (LFA-3, CD58) genes possess functional binding sites for the p53 tumor suppressor protein, ANTICANCER RESEARCH, Vol: 22, Pages: 4237-4241, ISSN: 0250-7005
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- Citations: 8
Kumar P, Athanasiou T, De L Stanbridge R, 2002, Treatment of long-duration atrial fibrillation by modified maze procedure., J R Soc Med, Vol: 95, Pages: 552-553, ISSN: 0141-0768
Perunovic B, Athanasiou A, Quilty RD, et al., 2002, Expression of mos in astrocytic tumors and its potential role in neoplastic progression, HUMAN PATHOLOGY, Vol: 33, Pages: 703-707, ISSN: 0046-8177
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- Citations: 11
Athanasiou T, DeL Stanbridge R, Kumar P, et al., 2002, Video assisted resternotomy in high-risk redo operations - the St Mary's experience., Eur J Cardiothorac Surg, Vol: 21, Pages: 932-934, ISSN: 1010-7940
The incidence of re-operative median sternotomy is rising. During resternotomy, catastrophic haemorrhage remains a dreaded complication. We describe our approach and experience with the combined use of Mayfield resternotomy retractor and anterior sternal retraction which allows division of adhesions between the sternum and mediastinal structures under direct vision with endoscopic or conventional instruments prior to resternotomy with a standard Hall reciprocating saw. The mean time to divide the retro-sternal adhesions was 26.4+/-16.7 min. No morbidity related to sternal division was observed. For redo surgery, repeat sternotomy under direct vision may reduce the sternotomy related morbidity (especially the need for cardiopulmonany bypass due to significant haemorrhage) and mortality.
Perunovic B, Pople IK, Athanasiou A, et al., 2002, Test and teach - A large tumour arising from the cribriform plate - Explanation and diagnosis: Intracranial schwannoma unrelated to a major cranial nerve, PATHOLOGY, Vol: 34, Pages: 74-77, ISSN: 0031-3025
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- Citations: 1
Perunovic B, Quilty RD, Athanasiou A, et al., 2001, Damage to intracranial optic pathways in fatal closed head injury in man, JOURNAL OF THE NEUROLOGICAL SCIENCES, Vol: 185, Pages: 55-62, ISSN: 0022-510X
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- Citations: 9
Gorgoulis VG, Zacharatos P, Mariatos G, et al., 2001, Deregulated expression of c-mos in non-small cell lung carcinomas: relationship with p53 status, genomic instability, and tumor kinetics, Cancer Res, Vol: 61, Pages: 538-549, ISSN: 0008-5472
Athanasiou A, Gorgoulis VG, Zacharatos P, et al., 2000, c-mos immunoreactivity is an indicator of good prognosis in lung cancer, HISTOPATHOLOGY, Vol: 37, Pages: 45-54, ISSN: 0309-0167
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- Citations: 9
Grapsa J, O'Regan D, Kourliouros A, et al., Non-Invasive Assessment May Have a Key Role in Follow-Up Performance of Modified Cabrol Aortic Root Reconstruction, HELLENIC JOURNAL OF CARDIOLOGY, Vol: 52, Pages: 545-550, ISSN: 1109-9666
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