Imperial College London

Professor Toby Maher

Faculty of MedicineNational Heart & Lung Institute

Professor of Interstitial Lung Disease
 
 
 
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Contact

 

+44 (0)20 7594 2151t.maher

 
 
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Assistant

 

Ms Georgina Moss +44 (0)20 7594 2151

 
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Location

 

364Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Maher:2023:10.1056/EVIDoa2300083,
author = {Maher, TM and Avram, C and Bortey, E and Hart, SP and Hirani, N and Molyneux, PL and Porter, JC and Smith, JA and Sciascia, T},
doi = {10.1056/EVIDoa2300083},
journal = {NEJM Evid},
title = {Nalbuphine Tablets for Cough in Patients with Idiopathic Pulmonary Fibrosis.},
url = {http://dx.doi.org/10.1056/EVIDoa2300083},
volume = {2},
year = {2023}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Nalbuphine for Cough with Idiopathic Pulmonary FibrosisIn patients with idiopathic pulmonary fibrosis, cough may have a negative impact on daily life. In a randomized, 22-day treatment period, placebo-controlled, crossover trial, extended-release nalbuphine (NAL ER), an opioid agonist-antagonist, was compared to placebo for cough control and adverse effects. During active treatment there was a 75.1% reduction in daytime objective cough frequency compared with 22.6% in the placebo treatment period. Nausea, fatigue, constipation, and dizziness were more common with NAL ER than with placebo.
AU - Maher,TM
AU - Avram,C
AU - Bortey,E
AU - Hart,SP
AU - Hirani,N
AU - Molyneux,PL
AU - Porter,JC
AU - Smith,JA
AU - Sciascia,T
DO - 10.1056/EVIDoa2300083
PY - 2023///
TI - Nalbuphine Tablets for Cough in Patients with Idiopathic Pulmonary Fibrosis.
T2 - NEJM Evid
UR - http://dx.doi.org/10.1056/EVIDoa2300083
UR - https://www.ncbi.nlm.nih.gov/pubmed/38320144
VL - 2
ER -