Infection and immunity
The groups in this research theme work on a wide variety of pathogens (protozoal and helminth parasites, fungi, bacteria and viruses) and hosts (mammals, fish, insects, nematodes and plants). Common areas include mechanisms of host immunity and analysis of complex host-pathogen interactions such as determinants of virulence and immune evasion mechanisms. Genetic manipulation of both host and pathogen is a feature of many strands of research, in addition to application of state of the art imaging technologies to investigate both cellular events and infection in vivo. This is complemented by work on the vertebrate immune system, with interests in haematopoiesis, NK cell development and function, inflammation and cytotoxicity.