Daniel Elson is a Professor of Surgical Imaging and Biophotonics in the Hamlyn Centre for Robotic Surgery, Institute of Global Health Innovation and Department of Surgery and Cancer at St. Mary's Hospital. Research interests are based around the development and application of photonics technology to medical imaging, including multispectral imaging, ultrasound mediated optical tomography, structured lighting, light sources in endoscopy and scattering spectroscopy.
Also see my research webpage:
Publications can be found on Google Scholar.
Recent publications are available here.
A list of current and previous lab members can also be found on my research webpage.
Fluorescence provides a powerful means of achieving molecular contrast in a wide range of biological and medical applications. For example, it can be used to detect the autofluorescence from naturally occurring fluorophores in biological tissues and can provide contrast between different states of diseased tissue. Targeted probes can also be applied that localize in specific cellular locations and provide extrinsic image contrast or that bind to specific receptors on the cell membrane. Over the past two decades not only have we seen remarkable advances in tissue diagnostic techniques based on fluorescence contrast, but we have also discovered the significant role that time-resolved or fluorescence lifetime techniques have to play in medical diagnosis. Until a decade ago progress in this area had been led by a small group of investigators; now many of the techniques are maturing and are ready to be adopted by innovative mainstream researchers and used in clinical settings. This broadly accessible book lays out the fundamentals, the state-of-the-art techniques and their current applications to help accelerate the use and proliferation of fluorescence techniques in tissue diagnostics for both research and clinical applications purposes.
et al., 2018, Dual-modality endoscopic probe for tissue surface shape reconstruction and hyperspectral imaging enabled by deep neural networks, Medical Image Analysis, Vol:48, ISSN:1361-8415, Pages:162-176
et al., 2018, Assessment of tissue polarimetric properties using Stokes polarimetric imaging with circularly polarized illumination, Journal of Biophotonics, Vol:11, ISSN:1864-063X
Qi J, He C, Elson DS, 2017, Real time complete Stokes polarimetric imager based on a linear polarizer array camera for tissue polarimetric imaging, Biomedical Optics Express, Vol:8, ISSN:2156-7085, Pages:4933-4946
et al., 2016, Aptamer-conjugated, fluorescent gold nanorods as potential cancer theradiagnostic agents, Materials Science & Engineering C - Biomimetic and Supramolecular Systems, Vol:59, ISSN:0928-4931, Pages:324-332
et al., 2015, Application of gold nanoparticles for gastrointestinal cancer theranostics: A systematic review, Nanomedicine-Nanotechnology Biology and Medicine, Vol:11, ISSN:1549-9634, Pages:2083-2098
et al., 2015, Intraoperative measurement of bowel oxygen saturation using a multispectral imaging laparoscope, Biomedical Optics Express, Vol:6, ISSN:2156-7085, Pages:4179-4190
et al., 2015, Dual shear wave induced laser speckle contrast signal and the improvement in shear wave speed measurement, Biomedical Optics Express, Vol:6, ISSN:2156-7085, Pages:1954-1962