Imperial College London

ProfessorMichaelLevin

Faculty of MedicineDepartment of Medicine

Chair in Paediatrics & International Child Health
 
 
 
//

Contact

 

+44 (0)20 7594 3760m.levin

 
 
//

Location

 

233Medical SchoolSt Mary's Campus

//

Summary

 

Summary

Michael Levin is currently Professor of Paediatrics & International Child Health  at Imperial College.  He trained in medicine in South Africa and in paediatrics in the UK before specialising in infectious diseases. He was Consultant in Infectious Diseases at Great Ormond Street hospital before being appointed as Professor of Paediatrics at Imperial College London in 1990. His research has focused on life threatening infections of childhood including meningococcal disease , childhood tuberculosis. Malaria, and Kawasaki disease, and severe respiratory infections.

Michael Levin currently heads an international EU-FP7 funded consortium studying the genetic basis of meningococcal and other life threatening bacterial infections of childhood.  He has also led an EUAid for poverty-related diseases project researching novel diagnostic methods for tuberculosis in Africa working with colleagues in Malawi and South Africa. He recently led an ESPID funded consortium studying the genetic basis of meningococcal disease, and is a co-investigator on the FEAST trial, with Professor Maitland, an MRC funded Phase III trial of fluids as supportive treatment for critical illness in African children.

Professor Levin's research group continues to study the pathophysiology and genetics of life threatening childhood infections, focusing on meningococcal disease, Kawasaki disease, and mycobacterial infection. The group are applying gene expression profiling and proteomic methods to understand pathophysiology of severe childhood ilnees, and are undertaking genome wide SNP studies linked to expression studies of meningococcal disease, Kawasaki disease and tuberculosis.

Selected Publications

Journal Articles

Kaforou M, Wright VJ, Levin M, 2014, Host RNA signatures for diagnostics: An example from paediatric tuberculosis in Africa, Journal of Infection, Vol:69, ISSN:0163-4453, Pages:S28-S31

Eleftherohorinou H, Hoggart CJ, Wright VJ, et al., 2011, Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways, Human Molecular Genetics, Vol:20, ISSN:0964-6906, Pages:3494-3506

More Publications