Imperial College London

Dr Anthony Laverty

Faculty of MedicineSchool of Public Health

Senior Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 5312a.laverty Website

 
 
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Location

 

322Reynolds BuildingCharing Cross Campus

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Summary

 

Publications

Publication Type
Year
to

176 results found

Been J, Laverty AA, Tsampi A, Filippidis FTet al., 2021, European progress in working towards a tobacco-free generation, European Journal of Pediatrics, Vol: 180, Pages: 3423-3431, ISSN: 0340-6199

Children have the right to grow up free from the hazards associated with tobacco smoking. Tobacco smoke exposure can have detrimental effects on children’s health and development, from before birth and beyond. As a result of effective tobacco control policies, European smoking rates are steadily decreasing among adults, as is the proportion of adolescents taking up smoking. Substantial variation however exists between countries, both in terms of smoking rates and regarding implementation, comprehensiveness and enforcement of policies to address smoking and second-hand smoke exposure. This is important because comprehensive tobacco control policies such as smoke-free legislation and tobacco taxation have extensively been shown to carry clear health benefits for both adults and children. Additional policies such as increasing the legal age to buy tobacco, reducing the number of outlets selling tobacco, banning tobacco display and advertising at the point-of-sale, and introducing plain packaging for tobacco products can help reduce smoking initiation by youth. At societal level, health professionals can play an important role in advocating for stronger policy measures, whereas they also clearly have a duty to address smoking and tobacco smoke exposure at the patient level. This includes providing cessation advise and referring to effective cessation services.Conclusion: Framing of tobacco exposure as a child right’s issue and of comprehensive tobacco control as a tool to work towards the ultimate goal of reaching a tobacco-free generation can help accelerate European progress to curb the tobacco epidemic.

Journal article

Goodman A, Laverty AA, Thomas A, Aldred Ret al., 2021, The impact of 2020 low traffic neighbourhoods on fire service emergency response times, in London, UK, Findings, Pages: 1-9

Between March and September 2020, 72 ‘Low Traffic Neighbourhoods’ (LTNs) were implemented in London. We examined the impact on fire brigade emergency response times in October 2020-February 2021 (‘post’), as compared to the same months in the previous two years (‘pre’). We found no evidence that response times inside the LTNs or on boundary roads were affected (e.g. pre/post change for first engine: -14 seconds inside LTNs; -11 seconds in the rest of London; p=0.4 for difference). Fire crews reported more delays due to ‘traffic calming measures’ in LTNs, but this was entirely offset by a decrease in delays for other reasons, particularly ‘traffic’. This was true both in LTNs that predominately blocked motor traffic using physical barriers (e.g. planters) and in LTNs using camera enforcement. These findings add to evidence that LTNs do not adversely affect emergency response times.

Journal article

Jenkins RH, Vamos EP, Taylor-Robinson D, Millett C, Laverty AAet al., 2021, Impacts of the 2008 Great Recession on dietary intake: a systematic review and meta-analysis, International Journal of Behavioral Nutrition and Physical Activity, Vol: 18, ISSN: 1479-5868

BackgroundThe 2008 Great Recession significantly impacted economies and individuals globally, with potential impacts on food systems and dietary intake. We systematically reviewed evidence on the impact of the Great Recession on individuals’ dietary intake globally and whether disadvantaged individuals were disproportionately affected.MethodsWe searched seven databases and relevant grey literature through June 2020. Longitudinal quantitative studies with the 2008 recession as the exposure and any measure of dietary intake (energy intake, dietary quality, and food/macronutrient consumption) as the outcome were eligible for inclusion. Eligibility was independently assessed by two reviewers. The Newcastle Ottawa Scale was used for quality and risk of bias assessment. We undertook a random effects meta-analysis for changes in energy intake. Harvest plots were used to display and summarise study results for other outcomes. The study was registered with PROSPERO (CRD42019135864).ResultsForty-one studies including 2.6 million people met our inclusion criteria and were heterogenous in both methods and results. Ten studies reported energy intake, 11 dietary quality, 34 food intake, and 13 macronutrient consumption. The Great Recession was associated with a mean reduction of 103.0 cal per adult equivalent per day (95% Confidence Interval: − 132.1, − 73.9) in high-income countries (5 studies) and an increase of 105.5 cal per adult per day (95% Confidence Interval: 72.8, 138.2) in middle-income countries (2 studies) following random effects meta-analysis. We found reductions in fruit and vegetable intake. We also found reductions in intake of fast food, sugary products, and soft drinks. Impacts on macronutrients and dietary quality were inconclusive, though suggestive of a decrease in dietary quality. The Great Recession had greater impacts on dietary intake for disadvantaged individuals.ConclusionsThe 2008 recession was associated

Journal article

Jenkins R, Aliabadi S, Vamos E, Taylor-Robinson D, Wickham S, Millett C, Laverty Aet al., 2021, The relationship between austerity and food insecurity in the UK: a systematic review, EClinicalMedicine, Vol: 33, Pages: 1-10, ISSN: 2589-5370

Background: In 2010, the UK government implemented austerity measures, involving reductions to public spending and welfare reform. We aimed to systematically review the relationship of austerity policies with food insecurity including foodbank use in the UK.Methods: We undertook a narrative systematic review (CRD42020164508) and searched seven databases, grey literature, and reference lists through September 2020. Studies with austerity policies (including welfare reform) as exposure and food insecurity (including foodbank use as a proxy) as study outcome were included. We included quantitative longitudinal and cross-sectional studies. Two reviewers assessed eligibility, extracted data directly from studies, and undertook quality assessment.Findings: Eight studies were included: two individual-level studies totalling 4129 participants and six ecological studies. All suggested a relationship between austerity and increased food insecurity. Two studies found that austerity policies were associated with increased food insecurity in European countries including the UK. Six studies found that the welfare reform aspect of UK austerity policies was associated with increased food insecurity and foodbank use. Sanctions involving delays to benefits as a response to a claimant not actively seeking work may increase food insecurity, with studies finding that increases of 100 sanctions per 100,000 people may have led to increases of between 2 and 36 food parcels per 100,000 population.Interpretation: UK austerity policies were consistently linked to food insecurity and foodbank use. Policymakers should consider impacts of austerity on food insecurity when considering how to reduce budget deficits.

Journal article

Laverty AA, Goodman A, Aldred R, 2021, Low traffic neighbourhoods and population, BMJ: British Medical Journal, Vol: 372, Pages: 1-2, ISSN: 0959-535X

Journal article

Laverty AA, Aldred R, Goodman A, 2021, The impact of introducing low traffic neighbourhoods on road traffic injuries, Findings, Pages: 1-8

We examine the impact on road traffic injuries of introducing low traffic neighbourhoods in Waltham Forest, London. Using Stats19 police data 2012-2019, we find a three-fold decline in number of injuries inside low traffic neighbourhoods after implementation, relative to the rest of Waltham Forest and the rest of Outer London. We further estimate that walking, cycling, and driving all became approximately 3-4 times safer per trip. There was no evidence that injury numbers changed on boundary roads. Our findings suggest that low traffic neighbourhoods reduce injury risks across all modes inside the neighbourhood, without negative impacts at the boundary.

Journal article

Seferidi P, Millett C, Laverty AA, 2021, Industry self-regulation fails to deliver healthier diets, again Public Health England's replacement must take bolder action, BMJ: British Medical Journal, Vol: 372, Pages: 1-2, ISSN: 0959-535X

Journal article

Laverty AA, Hone T, Goodman A, Kelly Y, Millett Cet al., 2021, Associations of active travel with adiposity among children and socioeconomic differentials: a longitudinal study, BMJ Open, Vol: 11, Pages: 1-9, ISSN: 2044-6055

Objectives Examine longitudinal associations between modes of travel to school and adiposity.Setting The UK.Participants 8432 children surveyed at ages 7, 11 and 14 years from the UK Millennium Cohort Study.Primary and secondary outcomes Objective percentage body fat and body mass index (BMI). Transport mode was categorised as private motorised transport, public transport and active transport (walking or cycling). Socioeconomic position (SEP) was measured by household income group and occupational social class. We adjusted analyses for changes in the country of UK, frequency of eating breakfast, self-reported growth spurts, hours of screen time and days per week of moderate-to-vigorous physical activity. Longitudinal (panel) regression models adjusting for individual fixed effects examined associations in changes in mode of travel to school and adiposity, controlling for both time-varying and time-invariant potential confounders. Interaction tests and stratified analyses investigated differences by markers of SEP.Results At age 14 years, 26.1% of children (2198) reported using private motorised transport, 35.3% (2979) used public transport and 38.6% (3255) used active transport to get to school. 36.6% (3083) of children changed mode two times between the three waves and 50.7% (4279) changed once. Compared with continuing to use private transport, switching to active transport was associated with a lower BMI (−0.21 kg/m2, 95% CI −0.31 to −0.10) and body fat (−0.55%, 95% CI −0.80% to −0.31%). Switching to public transport was associated with lower percentage body fat (−0.43%, 95% CI −0.75% to −0.12%), but associations with BMI did not reach statistical significance (−0.13 kg/m2, 95% CI −0.26 to 0.01). Interaction tests showed a trend for these effects to be stronger in more deprived groups, but these interactions did not reach statistical significance.Conclusion This longitudinal study during a key life

Journal article

Laverty AA, Millett C, Hopkinson NS, Filippidis FTet al., 2021, Introduction of standardised packaging and availability of illicit cigarettes: a difference-in-difference analysis of European Union survey data 2015-2018., Thorax, Vol: 76, Pages: 89-91

Standardised packaging of tobacco products is intended to reduce the appeal of smoking, but the tobacco industry claims this increases illicit trade. We examined the percentage of people reporting being offered illicit cigarettes before and after full implementation of standardised packaging in the UK, Ireland and France and compared this to other European Union countries. Reported ever illicit cigarette exposure fell from 19.8% to 18.1% between 2015 and 2018 in the three countries fully implementing the policy, and from 19.6% to 17.0% in control countries (p for difference=0.320). Standardised packaging does not appear to increase the availability of illicit cigarettes.

Journal article

Goodman A, Laverty AA, Aldred R, 2020, The impact of introducing a low traffic neighbourhood on fire service emergency response times, in Waltham Forest London, Findings

There is sometimes concern that low traffic neighbourhoods slow emergency vehicles. We test this using London Fire Brigade data (2012-2020) in Waltham Forest, where from 2015 low traffic neighbourhoods have been implemented. We find no evidence that response times were affected inside low traffic neighbourhoods, and some evidence that they improved slightly on boundary roads. However, while the proportion of delays was unchanged, the reasons given for delays initially showed some shift from ‘no specific delay cause identified’ to ‘traffic calming measures’. Our findings indicate that low traffic neighbourhoods do not adversely affect emergency response times, although while LTNs are novel this perception may exist among some crews.

Journal article

Laverty A, Millett C, Filippidis FT, 2020, Associations between cigarette prices and consumption in Europe 2004 - 2014, Tobacco Control, Vol: 30, Pages: 111-113, ISSN: 0964-4563

IntroductionWhile tobacco price increases are known to reduce smoking prevalence, these relationships may be blunted by the availability of budget cigarettes, promoted by the tobacco industry to maintain profits. There has been limited previous research on the impact of budget cigarettes on cigarette consumption and used data from Europe 2004-2014 to investigate this.MethodsAnnual population-weighted cigarette consumption per adult data come from the International Cigarette Consumption Database. Annual tobacco price data come from Euromonitor International for 23 European countries. We examined median prices as well as price differentials, operationalised as percentages obtained by dividing the difference between median and minimum prices by median price. We used a linear random-effects model to assess associations between these and cigarette consumption within-year and with a one-year time lag.ResultsCigarette consumption per capita has declined over the study period (-29.5 cigarettes per capita per year, 95% Confidence Intervals -46.8 to -12.1). Our analysis suggests that increases in cigarette price differentials, a marker of opportunities for smokers to switch to less expensive cigarettes, are associated with greater consumption in the same year (+6.4 for a 10% increase in differential, -40.0 to 52.6) and are associated with greater consumption the following year (+67.6, 25.8 to 109.5). ConclusionThese analyses suggest that even in Europe where tobacco taxes are relatively high compared with other regions, differential cigarette pricing strategies may undermine tobacco control. Further research is needed on links between tobacco price structures and consumption and policy design to maximise the effectiveness of tobacco tax.

Journal article

Filippidis F, Chang C-M, Blackmore I, Laverty Aet al., 2020, Prices and illicit trade of cigarettes in the European Union, a cross-sectional analysis, Nicotine and Tobacco Research, Vol: 22, Pages: 2271-2275, ISSN: 1462-2203

IntroductionWithin the context of the World Health Organization Framework Convention on Tobacco Control Protocol to Eliminate Illicit Trade in Tobacco Products and the impending revision of the EU directive on tobacco excise rules we assessed whether cigarettes price is linked to being offered illicit cigarettes.MethodsWe combined data being offered illicit cigarettes from the 2015 Special Eurobarometer Survey on Illicit Tobacco (N=27,672) with area-level data on Gross Domestic Product, unemployment, perceived corruption and sharing a border with a non-European Economic Area (non-EEA) state. We used the 2015 Weighted Average Price of cigarettes (WAP), which reflects the average price of a cigarette pack in each member state. We assessed associations between prices and illicit trade using 3-level ordered regression models.Results19.6% of respondents reported ever being offered illicit cigarettes, 6.4% repeatedly. In fully adjusted models WAP was not associated with being more likely to have been offered illicit market cigarettes more often (adjusted Odds Ratio=1.02, 95% Confidence Interval 0.91; 1.15). Sharing a border with a non-EEA member state was associated with increased likelihood of reporting being offered illicit cigarettes more often (1.73, 1.26;2.39).ConclusionThis study found no significant association between cigarette prices and reporting being offered illicit cigarettes; sharing a border with a non-EEA member state was linked to illicit trade. This study adds to evidence that increasing prices of cigarettes are not associated with illicit trade and that the focus should remain on securing supply chains, including through features such independent traceability systems.ImplicationsAfter adjusting for individual and regional factors, we did not identify an association between prices of cigarettes and likelihood of reporting being offered illicit cigarettes in the EU. Sharing a border with a non-EEA state however, was associated with increased likelihood of

Journal article

Parnham J, Millett C, Chang K, Laverty AA, von Hinke S, Pearson-Stuttard J, Vamos EPet al., 2020, Is the Healthy Start scheme associated with increased food expenditure in low-income families with young children in the United Kingdom?

<jats:title>ABSTRACT</jats:title><jats:sec><jats:title>Introduction</jats:title><jats:p>Healthy Start is a food assistance programme in the United Kingdom (UK) which aims to enable low-income families on welfare benefits to access a healthier diet through the provision of food vouchers. Healthy Start was launched in 2006 but remains under-evaluated. This study aims to determine whether participation in the Healthy Start scheme is associated with differences in food expenditure in a nationally representative sample of households in the UK.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Cross-sectional analyses of the Living Costs and Food Survey dataset (2010-2017). All households with a child (0-3 years) or pregnant woman were included in the analysis (n=4,869). Multivariable quantile regression compared the expenditure and quantity of fruit and vegetables (FV), infant formula and total food purchases. Four exposure groups were defined based on eligibility, participation and income (Healthy Start Participating, Eligible Non-participating, Nearly Eligible low-income and Ineligible high-income households).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Of 876 eligible households, 54% participated in Healthy Start. No significant differences were found in FV or total food purchases between participating and eligible non-participating households, but infant formula purchases were lower in Healthy Start participating households. Ineligible higher-income households had higher purchases of FV.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>This study did not find evidence of an association between Healthy Start participation and FV expenditure. Moreover, inequalities in FV purchasing persist in the UK. Higher participation and increased voucher value may be needed

Poster

Laverty AA, Vamos EP, Panter J, Millett Cet al., 2020, Road user charging: a policy whose time has finally arrived, The Lancet Planetary Health, Vol: 4, Pages: e499-e500, ISSN: 2542-5196

Journal article

Parnham JC, Laverty AA, Majeed A, Vamos EPet al., 2020, Half of children entitled to free school meals did not have access to the scheme during COVID-19 lockdown in the UK, Public Health, Vol: 187, Pages: 161-164, ISSN: 0033-3506

OBJECTIVES: The objectives of the study were to investigate access to free school meals (FSMs) among eligible children, to describe factors associated with uptake and to investigate whether receiving FSMs was associated with measures of food insecurity in the UK using the Coronavirus (COVID-19) wave of the UK Household Longitudinal Study. STUDY DESIGN: The study design was cross-sectional analyses of questionnaire data collected in April 2020. METHODS: Six hundred and thirty-five children who were FSM eligible with complete data were included in the analytic sample. Accessing a FSM was defined as receiving a FSM voucher or a cooked meal at school. Multivariable logistic regression was used to investigate (i) associations between characteristics and access to FSMs and (ii) associations between access to FSMs and household food insecurity measures. All analyses accounted for survey design and sample weights to ensure representativeness. RESULTS: Fifty-one percent of eligible children accessed a FSM. Children in junior schools or above (aged 8+ years) (adjusted odds ratio [AOR]: 11.81; 95% confidence interval [CI]: 5.54, 25.19), who belonged to low-income families (AOR: 4.81; 95% CI: 2.10, 11.03) or still attending schools (AOR: 5.87; 95% CI: 1.70, 20.25) were more likely to receive FSMs. Children in Wales were less likely to access FSMs than those in England (AOR: 0.11; 95% CI: 0.03, 0.43). Receiving a FSM was associated with increased odds of recently using a food bank but not reporting feeling hungry. CONCLUSIONS: In the month after the COVID-19 lockdown, 49% of eligible children did not receive any form of FSMs. The present analyses highlight that the voucher scheme did not adequately serve children who could not attend school during the lockdown. Moreover, more needs to be done to support families relying on income-related benefits, who still report needing to access a food bank. As the scheme may be continued in summer or in a potential second wave, large improve

Journal article

Laverty AA, Been JV, 2020, Two simple ways for governments to clear the air for children, The Lancet Public Health, Vol: 5, Pages: E465-E466, ISSN: 2468-2667

Journal article

Seferidi P, Laverty AA, Collins B, Bandosz P, Capewell S, O'Flaherty M, Millett C, Pearson-Stuttard Jet al., 2020, Potential impacts of post-Brexit agricultural policy on fruit and vegetable intake and cardiovascular disease in England: a modelling study, BMJ Nutrition, Prevention & Health, Vol: 3, ISSN: 2516-5542

Background Current proposals for post-Brexit agricultural policy do not explicitly incorporate public health goals. The revised agricultural policy may be an opportunity to improve population health by supporting domestic production and consumption of fruits and vegetables (F&V). This study aims to quantify the potential impacts of a post-Brexit agricultural policy that increases land allocated to F&V on cardiovascular disease (CVD) mortality and inequalities in England, between 2021 to 2030.Methods We used the previously validated IMPACT Food Policy model and probabilistic sensitivity analysis to translate changes in land allocated to F&V into changes in F&V intake and associated CVD deaths, stratified by age, sex and Index of Multiple Deprivation. The model combined data on F&V agriculture, waste, purchases and intake, CVD mortality projections and appropriate relative risks. We modelled two scenarios, assuming that land allocated to F&V would gradually increase to 10% and 20% of land suitable for F&V production.Results We found that increasing land use for F&V production to 10% and 20% of suitable land would increase fruit intake by approximately 3.7% (95% uncertainty interval: 1.6% to 8.6%) and 17.4% (9.1% to 36.9%), and vegetable intake by approximately 7.8% (4.2% to 13.7%) and 37% (24.3% to 55.7%), respectively, in 2030. This would prevent or postpone approximately 3890 (1950 to 7080) and 18 010 (9840 to 28 870) CVD deaths between 2021 and 2030, under the first and second scenario, respectively. Both scenarios would reduce inequalities, with 16% of prevented or postponed deaths occurring among the least deprived compared with 22% among the most deprived.Conclusion Post-Brexit agricultural policy presents an important opportunity to improve dietary intake and associated cardiovascular mortality by supporting domestic production of F&V as part of a comprehensive strategy that intervenes across the supply chain.

Journal article

Laverty AA, Millett C, Majeed A, Vamos EPet al., 2020, COVID-19 presents opportunities and threats to transport and health, Journal of the Royal Society of Medicine, Vol: 113, Pages: 251-254, ISSN: 0141-0768

Journal article

Parnham J, Laverty A, Majeed A, Vamos Eet al., 2020, Half of children entitled to free school meals do not have access to the scheme during the COVID-19 lockdown in the UK., Publisher: medRxiv

Objectives To investigate access to free school meals (FSM) among eligible children, to describe factors associated with uptake and investigate whether receiving FSM was associated with measures of food insecurity in the UK using the COVID-19 wave of the UK Household Longitudinal Study (UKHKS). Study design Cross sectional analyses of UKHLS COVID-19 wave data collected in April 2020. Methods UKHLS participants completed a COVID-19 questionnaire in April 2020. 635 children who were FSM eligible with complete data were included in the analytic sample. Accessing a FSM was defined as having receiving a FSM voucher or a cooked meal at school. Multivariable logistic regression was used to investigate (i) associations between characteristics and access to FSM and (ii) associations between access to FSM and household food insecurity measures. All analyses accounted for survey design and sample weights. Results 51% of eligible children accessed a FSM. Children in junior schools or above (aged 8+ years) (OR 11.81; 95% CI 5.54,25.19), who were low income (AOR 4.81; 95% CI 2.10,11.03) or still attending schools (AOR 5.87; 95% CI 1.70,20.25) were more likely to receive FSM. Children in Wales were less likely to access FSM than those in England (AOR 0.11; 95% CI 0.03,0.43). Receiving a FSM was associated with an increased odds of recently using a food bank, but not reporting feeling hungry. Conclusions In the month following the COVID-19 lockdown, 49% of eligible children did not receive any form of FSM. The present analyses highlight that the voucher scheme did not adequately serve children who could not attend school during the lockdown. Moreover, more needs to be done to support families relying on income-related benefits, who still report needed to access a foodbank. As scheme may be continued in summer or in second wave, large improvements will be needed to improve its reach.

Working paper

McKay A, Negi NS, Murukutla N, Laverty A, Puri P, Uttekar BV, Mullin S, Millett Cet al., 2020, Trends in tobacco, alcohol and branded fast-food imagery in Bollywood films, 1994-2013, PLoS One, Vol: 15, ISSN: 1932-6203

Background and aimsExposure to tobacco, alcohol and fast-food use in films is associated with initiation of these behaviours. India is the world’s largest film producer, but the extent of such imagery in Bollywood (Hindi cinema) films is unclear. We therefore aimed to describe the extent of and trends in tobacco, alcohol and fast-food imagery in Bollywood films, between 1994–2013.MethodsFor the 15 top-grossing films each year between 1994–2013, the number of five-minute intervals containing product images were determined separately for tobacco, alcohol and fast-food. Both the proportion of films containing at least one image occurrence, and occurrences per film, were described overall and by year. Negative binomial regression described associations between film rating and occurrences/film, and estimated time-trends in occurrences/film, adjusted for rating.ResultsWe analysed 93 U-rated (unrestricted), 150 U/A-rated (parental guidance for children aged <12 years) and 55 A-rated (restricted to adult audience) films, containing 9,226 five-minute intervals (mean intervals/film 30.8, SD 4.0). 70% (n = 210), 93% (n = 278) and 21% (n = 62) of films contained at least one tobacco, alcohol and fast-food occurrence, respectively. Corresponding total mean occurrences/film were 4.0 (SD 4.9), 7.0 (4.7) and 0.4 (0.9). Tobacco occurrences were more common in U/A films (incidence rate ratio 1.49, 95% confidence interval 1.06–2.09) and A films (2.95; 1.95–4.48) than U-rated films. Alcohol occurrences were also more common in A-rated films than U-rated films (1.48; 1.15–1.85). Tobacco occurrences/film became less common over the observed period (adjusted trend -4% per annum; -2 to -7%; p <0.001), while alcohol (+2%; 0–3%; p = 0.02), and fast food (+8%; 2–14%; p = 0.01) occurrences/film became more common.ConclusionsAlthough the extent of tobacco imagery in Bollywood films fell over 1994–2013, it is still frequently observed.

Journal article

Hopkinson NS, Rossi N, El-Sayed Moustafa J, Laverty AA, Quint JK, Freydin MB, Visconti A, Murray B, Modat M, Ourselin S, Small K, Davies R, Wolf J, Spector T, Steves CJ, Falchi Met al., 2020, Current tobacco smoking and risk from COVID-19: results from a population symptom app in over 2.4 million people, Publisher: Cold Spring Harbor Laboratory

Background The association between current tobacco smoking, the risk of developing COVID-19 and the severity of illness is an important information gap.Methods UK users of the COVID Symptom Study app provided baseline data including demographics, anthropometrics, smoking status and medical conditions, were asked to log symptoms daily from 24th March 2020 to 23rd April 2020. Participants reporting that they did not feel physically normal were taken through a series of questions, including 14 potential COVID-19 symptoms and any hospital attendance. The main study outcome was the association between current smoking and the development of “classic” symptoms of COVID-19 during the pandemic defined as fever, new persistent cough and breathlessness. The number of concurrent COVID-19 symptoms was used as a proxy for severity. In addition, association of subcutaneous adipose tissue expression of ACE2, both the receptor for SARS-CoV-2 and a potential mediator of disease severity, with smoking status was assessed in a subset of 541 twins from the TwinsUK cohort.Results Data were available on 2,401,982 participants, mean(SD) age 43.6(15.1) years, 63.3% female, overall smoking prevalence 11.0%. 834,437 (35%) participants reported being unwell and entered one or more symptoms. Current smokers were more likely to develop symptoms suggesting a diagnosis of COVID-19; classic symptoms adjusted OR[95%CI] 1.14[1.10 to 1.18]; >5 symptoms 1.29[1.26 to 1.31]; >10 symptoms 1.50[1.42 to 1.58]. Smoking was associated with reduced ACE2 expression in adipose tissue (Beta(SE)=-0.395(0.149); p=7.01×10-3).Interpretation These data are consistent with smokers having an increased risk from COVID-19.Funding Zoe provided in kind support for all aspects of building, running and supporting the app and service to all users worldwide. The study was also supported by grants from the Wellcome Trust, UK Research and Innovation and British Heart Foundation.

Working paper

Patterson R, Panter J, Vamos EP, Cummins S, Millett C, Laverty AAet al., 2020, Associations between commute mode and cardiovascular disease, cancer, and all-cause mortality, and cancer incidence, using linked Census data over 25 years in England and Wales: a cohort study, Lancet Planetary Health, Vol: 4, Pages: E186-E194, ISSN: 2542-5196

BackgroundActive travel is increasingly recognised as an important source of physical activity. We aimed to describe associations between commute mode and cardiovascular disease, cancer, and all-cause mortality.MethodsWe analysed data from the Office for National Statistics Longitudinal Study of England and Wales (ONS-LS), which linked data from the Census of England and Wales (henceforth referred to as the Census) for 1991, 2001, and 2011 to mortality and cancer registrations. The cohort included individuals traced in the ONS-LS who were economically active (ie, aged ≥16 years, not retired from work, and not a full-time carer). Commuting by private motorised transport, public transport, walking, and cycling were compared in terms of all-cause mortality, cancer mortality, cardiovascular disease mortality, and cancer incidence, using Cox proportional-hazards models with time-varying covariates. Models were adjusted for age, sex, housing tenure, marital status, ethnicity, university education, car access, population density, socioeconomic classification, Carstairs index quintile, long-term illness, and year entered the study, and were additionally stratified by socioeconomic group.FindingsBetween the 1991 Census and the 2011 Census, 784 677 individuals contributed data for at least one Census, of whom 394 746 were included in the ONS-LS and were considered to be economically active working-age individuals. 13 983 people died, 3172 from cardiovascular disease and 6509 from cancer, and there were 20 980 incident cancer cases. In adjusted models, compared with commuting by private motorised vehicle, bicycle commuting was associated with a 20% reduced rate of all-cause mortality (hazard ratio [HR] 0·80, 95% CI 0·73–0·89), a 24% decreased rate of cardiovascular disease mortality (0·76, 0·61–0·93), a 16% lower rate of cancer mortality (0·84, 0·73–0·98), and an 11% reduced rate of incident ca

Journal article

Laverty A, Hone T, Vamos EP, Anyanwu PE, Taylor Robinson D, de Vocht F, Millett C, Hopkinson NSet al., 2020, Impact of banning smoking in cars with children on exposure to second-hand smoke: a natural experiment in England and Scotland, Thorax, Vol: 75, Pages: 345-347, ISSN: 0040-6376

England banned smoking in cars carrying children in 2015 and Scotland in 2016. With survey data from three years for both countries (NEngland=3,483-6,920,NScotland=232-319), we used this natural experiment to assess impacts of the English ban using logistic regression within a difference-in-differences framework. Among children aged 13-15 years, self-reported levels of regular exposure to smoke in cars were 3.4% in 2012, 2.2% in 2014 and 1.3% in 2016 for Scotland and 6.3%, 5.9% and 1.6% in England. The ban in England was associated with a -4.1% (95%CI -4.9%;-3.3%) absolute reduction (72% relative reduction) in exposure to tobacco smoke among children.

Journal article

McKay A, Goodman A, van Sluijs E, Millett C, Laverty AAet al., 2020, Cycle training and factors associated with cycling among adolescents in England, Journal of Transport & Health, Vol: 16, Pages: 1-7, ISSN: 2214-1405

BackgroundCycling has the potential to encourage physical activity as well as advancing societal goals such as reducing carbon emissions; encouraging cycling is therefore a policy goal in many contexts. We analysed individual level data from the whole of England on factors associated with cycling among adolescents, including cycle training delivered by the age of 11 years in primary schools.MethodsData came from the nationally representative Millennium Cohort Study collected when participants were aged 13–15 years (adolescents). We assessed frequency of cycling at least once per week (regular cycling) and used logistic regression to assess how this differed across characteristics including demographic, health and environmental factors, as well as receiving cycle training (‘Bikeability’) in primary school.ResultsWe found that 21.0% of adolescents cycled at least once per week. In fully adjusted analyses, this was more common among boys than girls (32.5% vs. 9.4%, p < 0.001), and those in rural areas than urban areas (24.9% vs. 20.3%, p < 0.001). Adolescents in areas with higher prevalence of adult cycle commuting were more likely to cycle regularly (26.1% in high cycling areas vs. 19.3% in low cycling areas, p < 0.001). Participants offered cycle training in primary school were not more likely to cycle regularly as adolescents (21.7% vs. 22.3%, p = 0.528).DiscussionApproximately one in five adolescents in England cycles regularly, although being offered cycle training in primary school was not linked to greater cycling. Many of the factors associated with adolescent cycling are similar to those for adults and adolescents are more likely to cycle in areas with higher levels of adult cycling.

Journal article

Laverty AA, Vamos E, Millett C, Chang K, Filippidis F, Hopkinson Net al., 2019, Child awareness of and access to cigarettes – impacts of the point of sale display ban in England, Tobacco Control, Vol: 28, Pages: 526-531, ISSN: 0964-4563

Introduction England introduced a tobacco display ban for shops with >280 m2 floor area (‘partial ban’) in 2012, then a total ban in 2015. This study assessed whether these were linked to child awareness of and access to cigarettes.Methods Data come from the Smoking, Drinking and Drug Use survey, an annual survey of children aged 11–15 years for 2010–2014 and 2016. Multivariate logistic regression models assessed changes in having seen cigarettes on display, usual sources and ease of access to cigarettes in shopsResults During the partial display ban in 2012, 89.9% of children reported seeing cigarettes on display in the last year, which was reduced to 86.0% in 2016 after the total ban (adjusted OR 0.58, 95% CI 0.50 to 0.66). Reductions were similar in small shops (84.1% to 79.3%)%) and supermarkets (62.6% to 57.3%)%). Although the ban was associated with a reduction in the proportion of regular child smokers reporting that they bought cigarettes in shops (57.0% in 2010 to 39.8% in 2016), we did not find evidence of changes in perceived difficulty or being refused sale among those who still did.Discussion Tobacco point-of-sale display bans in England reduced the exposure of children to cigarettes in shops and coincided with a decrease in buying cigarettes in shops. However, children do not report increased difficulty in obtaining cigarettes from shops, highlighting the need for additional measures to tackle tobacco advertising, stronger enforcement of existing laws and measures such as licencing for tobacco retailers.

Journal article

Laverty AA, Kypridemos C, Seferidi P, Vamos EP, Pearson-Stuttard J, Collins B, Capewell S, Mwatsama M, Cairney P, Fleming K, O'Flaherty M, Millett Cet al., 2019, Quantifying the impact of the Public Health Responsibility Deal on salt intake, cardiovascular disease and gastric cancer burdens: interrupted time series and microsimulation study, Journal of Epidemiology and Community Health, Vol: 73, Pages: 881-887, ISSN: 0143-005X

Background In 2011, England introduced the PublicHealth Responsibility Deal (RD), a public-privatepartnership (PPP) which gave greater freedom to thefood industry to set and monitor targets for salt intakes.We estimated the impact of the RD on trends in saltintake and associated changes in cardiovascular disease(CVD) and gastric cancer (GCa) incidence, mortality andeconomic costs in England from 2011–2025.Methods We used interrupted time series modelswith 24 hours’ urine sample data and the IMPACTNCDmicrosimulation model to estimate impacts of changes insalt consumption on CVD and GCa incidence, mortalityand economic impacts, as well as equity impacts.Results Between 2003 and 2010 mean salt intake wasfalling annually by 0.20 grams/day among men and 0.12g/d among women (P-value for trend both < 0.001).After RD implementation in 2011, annual declines insalt intake slowed statistically significantly to 0.11 g/damong men and 0.07 g/d among women (P-values fordifferences in trend both P < 0.001). We estimated thatthe RD has been responsible for approximately 9900(interquartile quartile range (IQR): 6700 to 13,000)additional cases of CVD and 1500 (IQR: 510 to 2300)additional cases of GCa between 2011 and 2018. Ifthe RD continues unchanged between 2019 and 2025,approximately 26 000 (IQR: 20 000 to 31,000) additionalcases of CVD and 3800 (IQR: 2200 to 5300) cases ofGCa may occur.Interpretation Public-private partnerships such as theRD which lack robust and independent target setting,monitoring and enforcement are unlikely to produceoptimal health gains.

Journal article

Patterson RA, Webb E, Millett C, Laverty Aet al., 2019, Physical activity accrued as part of public transport use in England, Journal of Public Health, Vol: 41, Pages: 222-230, ISSN: 1741-3842

Background:Walking and cycling for transport (active travel) is an important source of physical activity with established health benefits. However, levels of physical activity accrued during public transport journeys in England are unknown.Methods:Using the English National Travel Survey 2010–14 we quantified active travel as part of public transport journeys. Linear regression models compared levels of physical activity across public transport modes, and logistic regression models compared the odds of undertaking 30 min a day of physical activity.Results:Public transport users accumulated 20.5 min (95% confidence interval=19.8, 21.2) a day of physical activity as part of public transport journeys. Train users accumulated 28.1 min (26.3, 30.0) with bus users 16.0 min (15.3, 16.8). Overall, 34% (32%, 36%) of public transport users achieved 30 min a day of physical activity in the course of their journeys; 21% (19%, 24%) of bus users and 52% (47%, 56%) of train users.Conclusion:Public transport use is an effective way to incorporate physical activity into daily life. One in three public transport users meet physical activity guidelines suggesting that shifts from sedentary travel modes to public transport could dramatically raise the proportion of populations achieving recommended levels of physical activity.

Journal article

Laverty AA, Filippidis FT, Taylor-Robinson D, Millett C, Bush A, Hopkinson NSet al., 2019, Smoking uptake in UK children: Analysis of the UK Millennium Cohort Study., Thorax, Vol: 74, Pages: 607-610, ISSN: 0040-6376

We used data from 11 577 children in the UK Millennium Cohort Study, collected at approximately 14 years of age (early teens), to assess characteristics associated with smoking, and generated regional estimates of numbers of smokers. 13.8% of UK early teens studied had ever smoked; 1.9% were current smokers. This corresponds to 2 28 136 and 39 653 (13-14 year olds) in the UK, respectively. Ever smoking risk increased if caregivers (26.0% vs 10.9%) or friends smoked (35.1% vs 4.0%), with a dose-response effect for friends' smoking. Caregiver and peer-group smoking remain important drivers of child smoking uptake and thus important targets for intervention.

Journal article

Hone T, Szklo AS, Filippidis F, Laverty A, Sattamini I, Been J, Vianna C, de Souza MC, de Almeida LM, Millett Cet al., 2019, Smoke-free legislation and neonatal and infant mortality in Brazil: a longitudinal quasi-experimental study, Tobacco Control, Vol: 29, Pages: 312-319, ISSN: 0964-4563

Objective To examine the associations of partial and comprehensive smoke-free legislation with neonatal and infant mortality in Brazil using a quasi-experimental study design.Design Monthly longitudinal (panel) ecological study from January 2000 to December 2016.Setting All Brazilian municipalities (n=5565).Participants Infant populations.Intervention Smoke-free legislation in effect in each municipality and month. Legislation was encoded as basic (allowing smoking areas), partial (segregated smoking rooms) or comprehensive (no smoking in public buildings). Associations were quantified by immediate step and longer term slope/trend changes in outcomes.Statistical analyses Municipal-level linear fixed-effects regression models.Main outcomes measures Infant and neonatal mortality.Results Implementation of partial smoke-free legislation was associated with a −3.3 % (95% CI −6.2% to −0.4%) step reduction in the municipal infant mortality rate, but no step change in neonatal mortality. Comprehensive smoke-free legislation implementation was associated with −5.2 % (95% CI −8.3% to −2.1%) and −3.4 % (95% CI −6.7% to −0.1%) step reductions in infant and neonatal mortality, respectively, and a −0.36 (95% CI −0.66 to−0.06) annual decline in the infant mortality rate. We estimated that had all smoke-free legislation introduced since 2004 been comprehensive, an additional 10 091 infant deaths (95% CI 1196 to 21 761) could have been averted.Conclusions Strengthening smoke-free legislation in Brazil is associated with improvements in infant health outcomes—particularly under comprehensive legislation. Governments should accelerate implementation of comprehensive smoke-free legislation to protect infant health and achieve the United Nation’s Sustainable Development Goal three.

Journal article

Patterson R, Webb E, Hone T, Millett C, Laverty AAet al., 2019, Associations of public transportation use with cardiometabolic health: a systematic review and meta-analysis, American Journal of Epidemiology, Vol: 188, Pages: 785-795, ISSN: 1476-6256

Public transport provides an opportunity to incorporate physical activity into journeys, but potential health impacts have not been systematically examined. Literature searches were carried out up to December 2017 using Medline, Embase, Transport Database, Scopus, Cochrane Library, opengrey.eu and Google. We identified longitudinal studies which examined associations between public transport and cardio-metabolic health including: adiposity, type II diabetes, and cardiovascular disease. We assessed study quality using the Newcastle-Ottawa Scale for cohort studies and performed meta-analyses where possible. Ten studies were identified, seven investigating use of public transport and three examining proximity to public transport. Seven studies used individual level data on changes in BMI with objective outcomes measured in six studies. Study follow-up ranged from one to ten years with three studies adjusting for non-transport physical activity. We found a consistent association between public transport use and lower BMI. Meta-analysis of data from five comparable studies found that switching from car to public transport was associated with lower BMI: −0.30 kg/m2 (−0.47, −0.14). Few studies have investigated associations between public transport use and non-adiposity outcomes. These findings suggest that sustainable urban design which promotes public transport use may produce modest reductions in population BMI.

Journal article

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