Imperial College London
Alternate

Dr Enrique Castro Sánchez

Faculty of Medicine, Department of Infectious Disease

Honorary Lecturer
 
 
 
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Contact

 

+44 (0)20 3313 2072e.castro-sanchez Website

 
 
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Location

 

8.N17Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Charani:2017:jac/dkx040,
author = {Charani, E and Gharbi, M and Moore, LSP and Castro, Sanchez E and Lawson, W and Gilchrist, M and Holmes, AH},
doi = {jac/dkx040},
journal = {Journal of Antimicrobial Chemotherapy},
pages = {1825--1831},
title = {The effect of adding a mobile health intervention to a multimodal antimicrobial stewardship programme across three teaching hospitals – an interrupted time series study},
url = {http://dx.doi.org/10.1093/jac/dkx040},
volume = {72},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Objectives To evaluate the impact of adding a mobile health (mHealth) decision support system for antibiotic prescribing to an established antimicrobial stewardship programme (ASP).    Methods In August 2011, the antimicrobial prescribing policy was converted into a mobile application (app). A segmented regression analysis of interrupted time series was used to assess the impact of the app on prescribing indicators using data (2008-2014) from a biannual point prevalence study (PPS) in medicine and surgery wards. There were six data points pre and six data points post-implementation.  Results There was an increase in compliance with policy (e.g. compliance with empirical therapy or expert advice) in medicine (6.48%, CI -1.25—14.20) and surgery (6.63%, CI 0.15—13.10) in the implementation period, with a significant sudden change in level in surgery (p<0.05). There was an increase, though not significant, in medicine (15.20%, CI 17.81—48.22) and surgery (35.97%, -3.72—75.66) in the percentage of prescriptions that had a stop/review date documented. The documentation of indication decreased in both medicine (-16.25%, CI -42.52—10.01) and surgery (-14.62%, CI -42.88—13.63).Conclusion Introducing the ‘app’ to an existing ASP had a significant impact on the compliance to policy in surgery, and a positive but not significant effect on documentation of stop/review date in both specialties.  The negative effect on the third indicator may have been due to existing ASP efforts. The broader value of providing an antimicrobial policy on a digital platform e.g. the reach and access to the policy, should be measured using indicators more sensitive to mHealth interventions.
AU  - Charani,E
AU  - Gharbi,M
AU  - Moore,LSP
AU  - Castro,Sanchez E
AU  - Lawson,W
AU  - Gilchrist,M
AU  - Holmes,AH
DO  - jac/dkx040
EP  - 1831
PY  - 2017///
SN  - 1460-2091
SP  - 1825
TI  - The effect of adding a mobile health intervention to a multimodal antimicrobial stewardship programme across three teaching hospitals – an interrupted time series study
T2  - Journal of Antimicrobial Chemotherapy
UR  - http://dx.doi.org/10.1093/jac/dkx040
UR  - http://hdl.handle.net/10044/1/44311
VL  - 72
ER  -
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