My group uses multidisciplinary approaches across structural and computational biology to uncover the molecular details of how lipids are used as signalling molecules in mitochondria. The lab is currently supported by a UKRI Future Leaders Fellowship awarded in 2020.
Khalid S, Rouse SL, 2020, Simulation of subcellular structures, Current Opinion in Structural Biology, Vol:61, ISSN:0959-440X, Pages:167-172
et al., 2019, Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins, Nature Communications, Vol:10, ISSN:2041-1723, Pages:1-15
et al., 2018, Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry, Science, Vol:362, ISSN:0036-8075, Pages:829-+
Rouse SL, Matthews SJ, Dueholm MS, 2018, Ecology and biogenesis of functional amyloids in pseudomonas, Journal of Molecular Biology, Vol:430, ISSN:0022-2836, Pages:3685-3695
et al., 2018, Structural basis of phosphatidic acid sensing by APH in apicomplexan parasites, Structure, Vol:26, ISSN:0969-2126, Pages:1059-1071.e6
et al., 2017, A new class of hybrid secretion system is employed in Pseudomonas amyloid biogenesis, Nature Communications, Vol:8, ISSN:2041-1723