Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Reader in Respiratory Medicine



+44 (0)1895 828




Harefield HospitalHarefield Hospital





William Man is Consultant Chest Physician at the Royal Brompton & Harefield NHS Foundation Trust and the National Heart & Lung Institute.

He qualified from Imperial College with a 1st class Honours BSc and Distinction Honours in MBBS. He went on to train in Respiratory and General Internal Medicine in London, and has received specialist training from some of the country’s leading teaching hospitals including the Royal Brompton Hospital, Hammersmith Hospital and St.Mary’s Hospital. He received a PhD (2007), funded by a MRC Clinical Research Training Fellowship. In 2006, Dr Man received the prestigious European Respiratory Society COPD award for “outstanding contribution to COPD research in Europe”. In 2008, he received a National Institute for Health Research Clinician Scientist award for clinicians who show exceptional promise for research. In 2011, he was awarded a New Investigator Research grant from the Medical Research Council, and in 2013, he was awarded one of five inaugural NIHR Clinical Trials Fellowships. In 2017, he received the American Thoracic Society Pulmonary Rehabilitation Career Achievement Award, and the Royal College of Physicians / National Institute for Health Research Clinical Research Network Award for research excellence from a NHS consultant. 

His clinical practice is based at both Harefield and Royal Brompton Hospitals, and involves the assessment and management of patients with advanced Chronic Obstructive Pulmonary Disease (COPD), other chronic lung diseases including interstitial lung diseases, and patients with sleep disorders, primarily obstructive sleep apnoea. He leads the Harefield Pulmonary Rehabilitation Unit, co-leads the Harefield Home Oxygen teams, and is research lead for Harefield Respiratory Medicine.

Dr. Man’s major research interests are pulmonary rehabilitation and skeletal muscle syndromes in patients with COPD and other chronic respiratory diseases. Dr Man heads the Harefield Respiratory Research team, which focuses on research in pulmonary rehabilitation, clinical trials in COPD and idiopathic pulmonary fibrosis, physical frailty and developing new outcome measures that reflect lower limb muscle function, sarcopaenia and cachexia in patients with chronic lung disease. Dr. Man has a particular interest in supporting allied health professionals though postgraduate research, and his research team comprises a multi-disciplinary group of allied health professionals.

Dr. Man has served on the writing committee for the British Thoracic Society Guideline on Pulmonary Rehabilitation in Adults (2013) and the joint American Thoracic Society/European Respiratory Society Executive Statement on Pulmonary Rehabilitation (2013), and is the current co-chair of the Guideline Development Group for the British Thoracic Society Guideline for Pulmonary Rehabilitation. He is a member of the British Thoracic Society Council and the British Thoracic Society Quality Improvement Group. Dr. Man has also held leadership positions within the American Thoracic Society Pulmonary Rehabilitation Assembly.

Selected Publications

Journal Articles

Barker RE, Jones SE, Banya W, et al., 2020, The effects of a video intervention on post-hospitalization pulmonary rehabilitation uptake: a randomized controlled trial., American Journal of Respiratory and Critical Care Medicine, Vol:201, ISSN:1073-449X, Pages:1517-1524

Kwan HY, Maddocks M, Nolan CM, et al., 2019, The prognostic significance of weight loss in chronic obstructive pulmonary disease-related cachexia: a prospective cohort study., Journal of Cachexia, Sarcopenia and Muscle, Vol:10, ISSN:2190-6009, Pages:1330-1338

Nolan CM, Maddocks M, Maher TM, et al., 2018, Gait speed and prognosis in patients with idiopathic pulmonary fibrosis: a prospective cohort study, European Respiratory Journal, Vol:53, ISSN:0903-1936, Pages:1-10

Maddocks M, Lovell N, Booth S, et al., 2017, Palliative care and management of troublesome symptoms for people with chronic obstructive pulmonary disease., The Lancet, Vol:390, ISSN:0140-6736, Pages:988-1002

Nolan CM, Maddocks M, Canavan JL, et al., 2016, Pedometer step count targets during pulmonary rehabilitation in COPD: a randomized controlled trial, American Journal of Respiratory and Critical Care Medicine, Vol:195, ISSN:1535-4970, Pages:1344-1352

Maddocks M, Kon SS, Canavan JL, et al., 2016, Physical frailty and pulmonary rehabilitation in COPD: a prospective cohort study, Thorax, Vol:71, ISSN:1468-3296, Pages:988-995

Maddocks M, Nolan CM, Man WD, et al., 2016, Neuromuscular electrical stimulation to improve exercise capacity in patients with severe COPD: a randomised double-blind, placebo-controlled trial., The Lancet Respiratory Medicine, Vol:4, ISSN:2213-2600, Pages:27-36

Kon SSC, Jones SE, Schofield SJ, et al., 2015, Gait speed and readmission following hospitalisation for acute exacerbations of COPD: a prospective study, Thorax, Vol:70, ISSN:1468-3296, Pages:1131-1137

Jones SE, Maddocks M, Kon SSC, et al., 2015, Sarcopenia in COPD: prevalence, clinical correlates and response to pulmonary rehabilitation, Thorax, Vol:70, ISSN:0040-6376, Pages:213-218

Kon SSC, Canavan JL, Jones SE, et al., 2014, Minimum clinically important difference for the COPD Assessment Test: a prospective analysis, Lancet Respiratory Medicine, Vol:2, ISSN:2213-2600, Pages:195-203

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