Research Assistant/Associate – Mechanisms of mechanotransduction in cartilage and bone formation

Job summary

The Developmental Biomechanics group is seeking to add a valuable new member to our research group. We are looking to appoint a Research Assistant/Associate to investigate mechanotransduction pathways involved in prenatal bone and cartilage development using a mechanostimulation bioreactor for in vitro culture of mouse limb explants. The project offers an exciting opportunity to apply organ/tissue culture techniques to developmental biology...

Job listing information

  • Reference ENG00592
  • Date posted 23 November 2018
  • Closing date 21 December 2018

Job description

Job summary

The Developmental Biomechanics group is seeking to add a valuable new member to our research group. We are looking to appoint a Research Assistant/Associate to investigate mechanotransduction pathways involved in prenatal bone and cartilage development using a mechanostimulation bioreactor for in vitro culture of mouse limb explants. The project offers an exciting opportunity to apply organ/tissue culture techniques to developmental biology and mechanobiology research questions, with relevance for tissue engineering and regenerative medicine applications. The researcher will be part of the exciting and world-renowned Department of Bioengineering at Imperial, based in the centre of the vibrant city of London.

Duties and responsibilities

The ideal candidate will start as soon as possible and make the most of this excellent opportunity. We especially value applicants from diverse backgrounds who can bring new skills and expertise. This project will be a collaboration between the Nowlan group at Imperial College London (https://developmental-biomechanics.org/) and the Hoey group at Trinity College Dublin, Ireland (https://www.tcd.ie/mecheng/staff/dahoey/).

To be considered for this position, you must have:
• An MEng or MSc or equivalent qualification in a relevant Bioengineering or Mechanical Engineering subject
• For appointment at Research Associate level: a PhD (or equivalent) in the Biomechanics or Bioengineering field, or equivalent research, industrial or commercial experience

You will have previous experience of using a bioreactor for in vitro culture of cells or tissues, and an in-depth knowledge of mechanoregulation and mechanotransduction. Experience with histological techniques, the murine model system and with developmental model systems are desired but not essential.

Essential requirements

You will have:
• An MEng or MSc or equivalent qualification in a relevant Bioengineering or Mechanical Engineering subject
• Practical, in-depth experience of using a bioreactor for in vitro culture of cells or tissues
• Track record of high-quality academic publications as main author in the Biomechanics or Biomedical Engineering field in international journals
• In-depth knowledge of mechanoregulation and mechanotransduction
• Knowledge of research methods, statistical procedures and imaging packages
• Self-motivation and an ability to exercise initiative and judgment in carrying out research tasks
• Ability to work both independently and as part of a team
• Competence at writing and presenting in scientific English at a level suitable for conference presentations and peer reviewed journal publications
• Excellent verbal communication skills and the ability to deal with a wide range of people
• Flexible attitude towards work

You will be:
• Willing to travel within the UK, to the project collaborator in Ireland, and otherwise abroad to conduct research and attend conferences
• Willing to work out of normal working hours (including weekends) if the requirements of the project demand.
• Able to prioritise jobs and organise work effectively to meet deadlines
• Able to contribute to a complex research programme
• Willing to work as part of a team and to be open-minded and cooperative
• Willing to undertake any necessary training for the role
• Willing to learn and operate good research practice, Health and Safety and Ethics Policies

Further information

Imperial College London is a science-based institution with the greatest concentration of high-impact research of any major UK university. The Faculty of Engineering, consistently rated among the best in the world, is made up of 10 academic departments and is committed to increasing its research activity by focusing on engineering-led multidisciplinary growth areas that target a number of global challenges. All of our academic departments are located on a single campus in South Kensington, giving a concentration of talent that creates a stimulating and vibrant research community. You can find out more about our staff benefits, including generous annual leave entitlements and our excellent professional development opportunities, here: http://www.imperial.ac.uk/job-applicants/staff-benefits/.

For informal enquiries about the post please contact Dr Niamh Nowlan at n.nowlan@imperial.ac.uk.

*Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £33,380 to £35,061 per annum.

Our preferred method of application is online via our website at http://www.imperial.ac.uk/jobs/. Enter the job vacancy reference number (ENG00592) into the search bar and select Apply Now. Further information is also available on the job description.

Please note: Interviews will be held on : 3/01/2019

Any queries regarding the application process should be directed to Jo Adam, i.adam@imperial.ac.uk.

Closing Date: 21/12/2018

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About Imperial College London

Imperial College London is the UK’s only university focussed entirely on science, engineering, medicine and business and we are consistently rated in the top 10 universities in the world.

You will find our main London campus in South Kensington, with our hospital campuses located nearby in West and North London. We also have Silwood Park in Berkshire and state-of-the-art facilities in development at our major new campus in White City.

We work in a multidisciplinary and diverse community for education, research, translation and commercialisation, harnessing science and innovation to tackle the big global challenges our complex world faces.

It’s our mission to achieve enduring excellence in all that we do for the benefit of society – and we are looking for the most talented people to help us get there.

Additional information

Please note that job descriptions cannot be exhaustive and the post-holder may be required to undertake other duties, which are broadly in line with the above key responsibilities.

All Imperial employees are expected to follow the 7 principles of Imperial Expectations: 

  • Champion a positive approach to change and opportunity
  • Communicate regularly and effectively within, and across, teams
  • Consider the thoughts and expectations of others
  • Deliver positive outcomes
  • Encourage inclusive participation and eliminate discrimination
  • Develop and grow skills and expertise
  • Work in a planned and managed way 

In addition to the above, employees are required to observe and comply with all College policies and regulations.

Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.