LOGO

The Section of Metabolic Medicine focusses on clinical diabetes research. The Section has developed an international reputation in health technology development and assessment, and is applying this to support people living with diabetes to self manage more effectively.

Research themes include closed-loop insulin delivery, novel small molecule sensing and personalised decision support using case based reasoning. The active technology research programmes are cross-faculty and multidisciplinary, incorporating expertise from the Faculty of Engineering and Faculty of Natural Sciences.

Imperial is the co-ordinating centre for the diabetes theme of the NIHR Clinical Research Network, and leads the ADDRESS-2 study of new onset type 1 diabetes.

We have partnered with Oxford Brookes UniversityUniversitat de GironaInstitut d'Investigació Biomèdica de GironaRomsoft and cellnovo to bring together computer scientists, clinicians and industry leaders to create a personalised decision support system for diabetes management – the PEPPER project.

In addition to working toward revolutionising diabetes self management we are harnessing technology to address the growing challenges of diabetes diagnosis in a young, multi-ethnic population using a combination of genomic, biochemical and clinical parameters to ensure people with new onset diabetes receive the appropriate treatment – the MY DIABETES Study. This work is in collaboration with Imperial BRC Genomics Facility.

The Section is also addressing the growing prevalence of type 2 diabetes with diabetes prevention studies using text messaging technology and pharmacology, and contributes to both undergraduate and postgraduate medical education within the Faculty of Medicine.

Research

Studies

ADDRESS-2 study - learning about the characteristics of people newly diagnosed with type 1 with diabetes in the UK and supporting other research into type 1 diabetes.

ABC4D study - Advanced Bolus Calculator for Diabetes.

BiAP study Clinical Evaluation of an Artificial Pancreas in people with Type 1 Diabetes. Publication found here.

I HART CGM study - Comparison of Continuous Glucose Monitoring vs. Flash Glucose Monitoring in Type 1 diabetes. Publication found here.

PEPPER study - Personalised Decision Support system for diabetes management in Type 1 Diabetes.

MY DIABETES study - Characterising Young-Onset Diabetes in two UK ethnic groups, specifically identifying potential genetic causes to their diabetes known as Maturity Onset Diabetes of the Young (MODY).

WynnMet - The Wynn Database: Metabolic Risk Factors and Mortality

 

Other Research Areas

  • Using intelligent systems e.g. health apps to support Type 1 Diabetes 
  • Using mobile technology to promote lifestyle changes to prevent Type 2 diabetes
  • Cardiovascular risk
  • Complications of pregnancy
  • Type 2 diabetes

Head of Metabolic Medicine

Professor Desmond Johnston leads a team of researchers investigating early changes in insulin secretion and insulin sensitivity, and other aspects of metabolism in people predisposed to Type 2 diabetes before diabetes develops. He is also interested in the mechanisms underlying the premature vascular disease to which people with diabetes are prone and in the associated metabolic disturbances such as non-alcoholic fatty liver disease.  He has published hundreds of research papers on this and other related areas.

Further information on Professor Johnston

Research Team

Dr Rochan Agha-Jaffar

Silouhette

Dr Rochan Agha-Jaffar

Dr Parizad Avari

Silouhette

Dr Parizad Avari

Mrs Heather Bones

H Bones

Mrs Heather Bones

Dr Ian Godsland

Dr Ian Godsland

Dr Ian Godsland

Dr Neil Hill

Silouhette

Dr Neil Hill

Prof Desmond Johnston

Professor Desmond Johnston

Prof Desmond Johnston

Ms Narvada Jugnee

Silouhette

Ms Narvada Jugnee

Ms Akaal Kaur

Silouhette

Ms Akaal Kaur

Dr Shivani Misra

S Misra

Dr Shivani Misra

Ms Kanchana Ngaosuwan

Silouhette

Ms Kanchana Ngaosuwan

Prof Nick Oliver

Nick Oliver

Prof Nick Oliver

Dr Monika Reddy

Silouhette

Dr Monika Reddy

Miss Sian Rilstone

Silouhette

Miss Sian Rilstone

Mr Weerachai Srivanichakorn

Silouhette

Mr Weerachai Srivanichakorn

Ms Maria Thomas

Silouhette

Ms Maria Thomas

Ms Hazel Thomson

Silouhette

Ms Hazel Thomson

Dr Chukwuma Uduku

Silouhette

Dr Chukwuma Uduku

Dr Helen Walkey

Silouhette

Dr Helen Walkey

Privacy

Privacy Statement

You can view our privacy statement here:

Privacy Statement.pdf