Section of Molecular Immunology

The research in the Section of Molecular Immunology focuses on investigating the fundamental processes underlying immune responses, in particular, the development and maintenance of T cells.

A focus of research within the Section is also the immune response to dengue virus infection, which is one of the biggest threats to public health in a number of developing countries. Research within the Section has demonstrated that antibodies may contribute to the disease process during the secondary infection, which tends to be more severe.

The Section is supported by funding from the Wellcome Trust, Medical Research Council, Leukaemia Research Fund, the Biotechnology and Biological Sciences Research Council, the National Institute of Health (NIH) and European Commission Seventh Framework Program.

In addition to its research programme, the Section of Molecular Immunology is responsible for delivering the Imperial College MSc in Immunology, and is a core contributor to the intercalated BSc in Immunology and the Immunology short course for clinicians and scientists.

Research groups and Section leadership

Research interests and areas


  • T cell Immunology and lymphocyte homeostasis
  • T cell development
  • Immunopathogenesis of dengue haemorrhagic fever
  • Genetics of T cells

Head of Molecular Immunology


Professor Marina Botto
Professor Marina Botto, FMedSci, is the Director of the Centre for Complement and Inflammation Research. She is Professor of Rheumatology, Honorary Consultant Rheumatologist, and the Director of the Bioservices at Imperial College. The focus of her research programme is to understand how the innate immune system, in particular, the complement system, contributes to the pathogenesis of systemic lupus erythematosus (SLE), an autoimmune disease affecting several organs.

Find out more about Professor Botto

Research group leads