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Circadian Neuroscience in Brain Health and Disease

Working to identify the molecular mechanisms, cellular players and emergent network interactions driving circadian and sleep function, and their disruption in the early stages of Alzheimer’s disease

HI

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Research

Read more about our work using live imaging and in vivo gene therapy techniques to investigate the role circadian rhythms play in dementia
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Lab members

Meet our team of researchers, past and present

Join the lab

We are always keen to hear from talented scientists interested in joining our lab - get in touch today!

Featured news

  • In the media
  • December 2025
The ‘silent’ brain cells that shape our behaviour, memory and health

New article in Nature discusses discoveries made studying astrocytes - the previously overlooked support cells in the brain
  • In the media
  • January 2025
Research from the Brancaccio lab featured in Heliox podcast

The episode dived into the role of astrocytes and their production of GABA in orchestrating our internal clocks
Woman holds her hand up to her mouth and yawns
  • Research
  • December 2024
New paper reveals ‘chemical metronome’ helps the brain to keep time

Researchers led by Dr Marco Brancaccio, have uncovered a ‘chemical metronome’ in the brain, which helps to synchronise our sleeping patterns
  • Research
  • April 2024
How temperature and circadian rhythms intersect to regulate a protective protein

New study led by Dr Marco Brancaccio offers a deeper insight into how a neuroprotective pathway is regulated

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