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@article{Southworth-Davies:2026:10.1107/S2059798326008612,
author = {Southworth-Davies, RJ and Murray, JW and Carmichael, I and Rudiño-Piñera, E and Weik, M and Garman, EF},
doi = {10.1107/S2059798326008612},
journal = {Acta Crystallogr D Struct Biol},
title = {Separating the effects of temperature and absorbed X-ray dose on unit-cell volume.},
url = {http://dx.doi.org/10.1107/S2059798326008612},
year = {2026}
}
TY - JOUR
AB - The behaviour of the unit-cell volume of crystals of the iron-storage molecule ferritin, both in the apo and the holo form, and of influenza A virus subtype N9 neuraminidase at 100K and over a controlled cryo-temperature series was investigated. The purpose of this study was to separate out the effects of dose and temperature on the protein by assessing the changes in the unit-cell volume. Over the wide range of X-ray doses examined in this work, the irreversible effect of dose on the unit-cell volume could be distinguished from the reversible (below 160K) temperature-induced effects. Specific structural damage effects were not reversible.
AU - Southworth-Davies,RJ
AU - Murray,JW
AU - Carmichael,I
AU - Rudiño-Piñera,E
AU - Weik,M
AU - Garman,EF
DO - 10.1107/S2059798326008612
PY - 2026///
TI - Separating the effects of temperature and absorbed X-ray dose on unit-cell volume.
T2 - Acta Crystallogr D Struct Biol
UR - http://dx.doi.org/10.1107/S2059798326008612
UR - https://www.ncbi.nlm.nih.gov/pubmed/42741972
ER -