In 2012 the National Centre for Infection Prevention and Management launched a new e-learning package on Clostridium difficile (C. diff). This was an initiative to build on the C. diff infection prevention and control policy and the guidance on the clinical management of this disease to make the core information available in a user-friendly format.

The module lasts about ten minutes and includes a clinical case with a timeline guiding the user through the different stages of a clinical pathway for a patient who develops C. diff disease.

The tool is best suited for clinical and nursing staff, although it is focused on junior medical staff. It also includes a self-assessment quiz to reinforce key messages about clinical assessment.


Additional resources

  • Antibiotic prescribing smartphone app for Trust staff for iPhone and Android
  • Department of Health Start Smart - Then Focus guidance
  • Imperial College Healthcare NHS Trust's guidelines for treatment and management of C. diff
  • Imperial College Healthcare NHS Trust's policy on management of C. diff
  • Imperial College Healthcare NHS Trust's Start Smart Then Focus campaign
  • Useful reference: Improving the quality of antibiotic prescribing in the NHS by developing a new Antimicrobial Stewardship Programme:Start Smart—Then Focus
  • The National Centre for Infection Prevention and Management's website

Technical issues

  • Internet Explorer 8 - If you are using this web browser you may find that when you attempt to access the Case Study in the e-learning you will need to click to "no" if a yes/no box appears asking you about secure content.
  • Internet Explorer 9 - If you are using this web browser you may find that when you attempt to access the Case Study in the e-learning you will need to click "show all content" if a yellow bar pops up at the top or bottom of your screen.
  • Please use Google Chrome or Mozilla Firefox browsers which do not produce these issues.

Update - August 2013

Since this e-learning tool was created an additional drug, Fidaxomicin, has become available for the treatment of C. diff. Guidance on prescribing this drug is included in the Trust's policy on management of C. diff (please click on the link above).

A new algorithm for management of C. diff has also become available. This algorithm is included in the Adult Treatment of Infection Policy (please click on the link above).