Professor Vincenzo De Paola

Professor of Translational Neuroscience at Duke-NUS Medical School Singapore & Imperial College London

Biography

Professor Vincenzo De Paola is a Visiting Professor at Imperial College London and a translational neuroscientist working at the interface of human neuroscience, disease modelling and precision genetic medicines. He established his independent research programme at Imperial in 2007 and subsequently led translational neuroscience research at Duke-NUS Medical School in Singapore. His laboratory combines human genetics, single-cell multiomics, patient-derived neural models and humanised in vivo systems to identify mechanisms of neurological disease and translate them into therapeutic strategies. His recent work in Down syndrome, published in Nature Medicine, identified dosage-sensitive regulatory drivers of altered human brain development and has led to new RNA-based therapeutic approaches targeting these mechanisms.

Presentation

Genetic drivers in Down’s Syndrome: potential for therapeutic interventions?

Thursday 26 November 09.30