In this section
@article{Penner:2026:10.1097/INF.0000000000005371,
author = {Penner, J and Poletti, de Chaurand V and Seery, P and Burkhardt, I and Rosadas, C and Greiller, C and Randell, P and Lyall, H and Taylor, G},
doi = {10.1097/INF.0000000000005371},
journal = {Pediatr Infect Dis J},
title = {Timing of Loss of Transplacental Antibodies in Infants Born to Mothers Living With Human T-cell Lymphotropic Virus Type 1.},
url = {http://dx.doi.org/10.1097/INF.0000000000005371},
year = {2026}
}
TY - JOUR
AB - BACKGROUND: To date, evidence suggesting the optimal timing of antibody testing in human T-cell lymphotropic virus type 1 (HTLV-1)-exposed infants is lacking. Testing HTLV-1-exposed infants must balance the need for repeat testing if done too early while minimizing loss to follow-up with protracted follow-up intervals. METHODS: Single-center, retrospective cohort analysis of HTLV-1 serologic testing and breastfeeding practices in infants born to HTLV-1 seropositive pregnant individuals between 01/01/2016 and 10/03/2026. RESULTS: Nineteen children were identified, of whom 5 had positive serological tests for HTLV-1 when first tested, and 14 were seronegative on the first sample, with a median age at first negative test of 18.4 months (95% confidence interval: 6.9). None have been confirmed infected. Six children were known to have breast/chest-fed for an average of 4.5 months. CONCLUSIONS: Serologic testing of HTLV-1-exposed infants can be done at 18 months, minimizing persistent transplacental positives and follow-up attrition.
AU - Penner,J
AU - Poletti,de Chaurand V
AU - Seery,P
AU - Burkhardt,I
AU - Rosadas,C
AU - Greiller,C
AU - Randell,P
AU - Lyall,H
AU - Taylor,G
DO - 10.1097/INF.0000000000005371
PY - 2026///
TI - Timing of Loss of Transplacental Antibodies in Infants Born to Mothers Living With Human T-cell Lymphotropic Virus Type 1.
T2 - Pediatr Infect Dis J
UR - http://dx.doi.org/10.1097/INF.0000000000005371
UR - https://www.ncbi.nlm.nih.gov/pubmed/42587363
ER -