Challenges and opportunities in optical tomography

In optical tomography light does not behave in the ideal way that X-rays do in X-ray computed tomography.

Effects of diffraction, refraction, and scattering can severely affect the image quality in optical tomography when not properly taken into account.

In this presentation I will show how these effects can be mitigated by using physical measurement principles

and computational image reconstructions algorithms. Results of tomographic reconstructions of zebrafish

demonstrate the opportunities optical tomography offers for high resolution imaging of small animals.