In this section
@article{Martins:2026:10.1016/j.trac.2026.118879,
author = {Martins, TS and Bott-Neto, JL and Torrisi, F and Oliveira, ON},
doi = {10.1016/j.trac.2026.118879},
journal = {TrAC. Trends in analytical chemistry},
title = {Nanomaterial-enabled point-of-care technologies for pesticide biomonitoring in human biofluids: from detection strategies to real-world deployment},
url = {http://dx.doi.org/10.1016/j.trac.2026.118879},
volume = {201},
year = {2026}
}
TY - JOUR
AB - This review surveys recent advances in point-of-care testing (POCT) technologies for pesticide biomonitoring in human biofluids, with emphasis on urine and blood. We focus on electrochemical and colorimetric strategies that use functional nanomaterials to improve portability, reduce operational costs, and simplify sample handling relative to centralised laboratory immunoassays and chromatography–mass spectrometry. Progress in metallic nanoparticles, carbon-based and two-dimensional materials, conductive polymers, and reticular porous frameworks is discussed alongside hybrid architectures and antifouling interfaces. A comparative analysis highlights practical trade-offs among sensitivity, selectivity, time-to-result, and operational simplicity. Despite improved analytical performance, most POCT platforms remain at the proof-of-concept stage and lack validation under physiologically representative or field conditions, underscoring the need for standardised evaluation protocols and regulatory alignment. Finally, we discuss scalable manufacturing, sustainability, data governance, and the integration of machine learning and artificial intelligence as enabling routes for materials discovery, automated signal interpretation, and population-level surveillance of pesticide exposure.
AU - Martins,TS
AU - Bott-Neto,JL
AU - Torrisi,F
AU - Oliveira,ON
DO - 10.1016/j.trac.2026.118879
PY - 2026///
SN - 0165-9936
TI - Nanomaterial-enabled point-of-care technologies for pesticide biomonitoring in human biofluids: from detection strategies to real-world deployment
T2 - TrAC. Trends in analytical chemistry
UR - http://dx.doi.org/10.1016/j.trac.2026.118879
UR - https://www.sciencedirect.com/science/article/pii/S0165993626002360?via%3Dihub
VL - 201
ER -
Dr Felice Torrisi
Senior Lecturer in Chemistry of Two-Dimensional Materials
401A
Molecular Sciences Research Hub
White City Campus
f.torrisi@imperial.ac.uk
+44 (0)20 7594 5818