About the platforms 

ATLAS hosts two automated platforms dedicated to materials synthesis and development, and a third to prepare samples for analysis. 

FLEX AUTOPLANT

High-pressure synthesis and process development

  • Volumetric liquid handling tool with four 10 mL aspiration/dispense channels 
  • GDU-P(fd) gravimetric solid dispensing tool with 0.1 mg resolution balance
  • Simultaneous reaction in six 100 mL stainless steel reactors
  • Independent overhead mixing, temperature (-20 — 250 °C) and pressure (1 - 90 bar) control
  • Gas manifold for automated gaseous atmosphere control
  • Sampling and continuous feeding during reaction, including at pressure
  • Liquid/liquid extraction, solid phase extraction and vacuum filtration

FLEX ISYNTH

Parallel synthesis, formulation optimisation and crystallisation experiments

  • Volumetric liquid handling tool with three 10 mL aspiration/dispense channels and one vacuum filtration channel
  • GDU-P(fd) gravimetric solid dispensing tool with 0.1 mg resolution balance 
  • Reaction block with integrated reflux condenser and controlled shaking for 24 x 20 mL parallel reactions 
  • Temperature control from -20 — 150 °C
  • Ambient or inert atmosphere

 

The FLEX ISYNTH deck layout, containing filter tip racks (left), vial racks (centre) and the reaction block (right)

 

FLEX SWILE 

Sample preparation for analysis

  • Volumetric liquid handling tool with four 10 mL aspiration/dispense channels
  • SWILE gravimetric solid dispensing tool with 0 - 100 mg weighing range, 0.1 mg resolution
  • Shaking rack for three microwell plates or vial racks
  • Temperature control from -20 — 150 °C

 

The FLEX SWILE layout, consisting of a shaking rack (left), reagent vial racks (centre), the SWILE tool (bottom right) and the swins used by the SWILE tool to pick up reagent (bottom centre)