In this section
@inbook{Sarkis:2023:10.1016/B978-0-443-15274-0.50543-6,
author = {Sarkis, M and Fung, J and Lee, MH and Bernardi, A and Shah, N and Papathanasiou, MM},
booktitle = {Computer Aided Chemical Engineering},
doi = {10.1016/B978-0-443-15274-0.50543-6},
pages = {3405--3410},
title = {Integrating environmental sustainability in next-generation biopharmaceutical supply chains},
url = {http://dx.doi.org/10.1016/B978-0-443-15274-0.50543-6},
year = {2023}
}
TY - CHAP
AB - Maximizing product availability to the public and minimizing costs are primary objectives in the biopharmaceutical sector. Nevertheless, awareness of the environmental sustainability of supply chain operations is becoming increasingly relevant in recent years. To assist decision-makers in balancing financial and environmental sustainability we present an optimization framework which determines candidate supply chain structures network designs and operational plans. Supply chain structures are assessed with respect to total cost and environmental score, with the latter integrating environmental impacts related to climate change, water usage and energy consumption. A Pareto set of candidate solutions is found which provides insights in complex trade-offs between impact categories and cost: centralized manufacturing is selected to lower unit production cost and better use water resources, whilst decentralized manufacturing improves energy usage. Emissions from CO<inf>2</inf> are lowered through cost minimization.
AU - Sarkis,M
AU - Fung,J
AU - Lee,MH
AU - Bernardi,A
AU - Shah,N
AU - Papathanasiou,MM
DO - 10.1016/B978-0-443-15274-0.50543-6
EP - 3410
PY - 2023///
SP - 3405
TI - Integrating environmental sustainability in next-generation biopharmaceutical supply chains
T1 - Computer Aided Chemical Engineering
UR - http://dx.doi.org/10.1016/B978-0-443-15274-0.50543-6
ER -