Harkamaljot Kandail
Biography
2016
Post-Doctoral Scholar, Department of Biomedical Engineering, Marquette University and Medical College of Wisconsin, USA
2012 - 2016
PhD and DIC in Chemical Engineering, Imperial College London, UK
2008 - 2012
MEng (Hons.) and ACGI in Chemical with Nuclear Engineering, Imperial College London, UK
Research Interests
Applied mathematical modelling, more specifically, amalgamation of clinical imaging modalities such as CT and MRI with computational cardiovascular haemodynamics. The main objective of my research is to elucidate the role of blood flow in cardiovascular disease progression such as atherosclerosis and AAA; along with designing novel biomedical devices to treat these diseases. Current approaches include computational fluid and solid mechanics along with fluid-structure interaction.
Project Title
Computational Analysis of Stent-Graft Designs for Endovascular Repair of Complex Abdominal Aortic Aneurysms.
Endovascular aneurysm repair (EVAR) is a minimally invasive treatment procedure for AAA; however until recently some patients were unsuitable for EVAR due to adverse aortic neck morphology. Fenestrated- and branched-EVAR is an evolution of EVAR where AAA is treated using fenestrated stent-grafts (FSG) and branched stent-grafts (BSG), respectively. FSG shows promising short to mid-term results but the question of long term durability remains unanswered. Part of this PhD project is to answer the question of durability of FSG by simulating perioperative changes in blood flow in AAA as well as renal and iliac arteries. BSG are novel stent-grafts which are still in the design phase, therefore the second objective of this PhD project is to assess the functionality of BSG and to quantify their performance against FSG. Answering these aforementioned questions will enable to broaden the scope of endovascular surgery for AAA patients.
Supervisors
Department of Chemical Engineering, Imperial College London, UK
Dr Mo Hamady
Department of Interventional Radiology, St Mary’s Hospital, Imperial College London, UK
Publications
Kandail, H., Hamady, M. and Xu, X. Y. (2016). “Haemodynamic Functions of Fenestrated Stent-Graft under Resting, Hypertension and Exercise Conditions.” Frontiers in Surgery, DOI: 10.3389/fsurg.2016.00035.
Kandail, H., Hamady, M. and Xu, X. Y. (2016). “Effect of Flared Renal Stent on the Performance of Fenestrated Stent-Grafts at Rest and Exercise Conditions.” Journal of Endovascular Therapy, DOI: 10.1177/1526602816651425.
Kandail, H., Hamady, M. and Xu, X. Y. (2015). “Comparison of Blood Flow in Branched and Fenestrated Stent-grafts for Endovascular Repair of Abdominal Aortic Aneurysms.” Journal of Endovascular Therapy 22, 578-590.
Kandail, H., Hamady, M. and Xu, X. Y. (2014). “Patient-specific Analysis of Displacement Forces Acting on Fenestrated Stent Grafts for Endovascular Aneurysm Repair.” Journal of Biomechanics 47, 3546-3554.
Conferences
Kandail, H., Hamady, M. and Xu, X. Y. (2014). “Patient-specific Analysis of Drag Forces in Fenestrated Stent Graft for Abdominal Aortic Aneurysm: Effect of Exercise and Hypertension.” International Journal of Computer Assisted Radiology and Surgery 9 (Suppl 1), S43-S44.
Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C 2015), Snowbird resort, Utah, USA, 17-20 June 2015 (Podium presentation).
27th Annual scientific meeting of British Society of Interventional Radiology (BSIR 2014), BT Convention Centre, Liverpool, UK, 12-14 November 2014 (Podium presentation). Presentation link.
7th World Congress of Biomechanics (WCB 2014), John B. Hynes Veterans Memorial Convention Center, Boston, Massachusetts, USA, 6-11 July 2014 (Podium presentation).
28th International Congress of Computer Assisted Radiology and Surgery (CARS 2014), Fukuoka International Congress Center, Fukuoka, Japan, 25-28 June 2014 (Podium presentation).
26th Annual scientific meeting of British Society of Interventional Radiology (BSIR 2013), Manchester Central Convention Centre, Manchester, UK, 13-15 November 2013 (Podium presentation). Presentation link.
37th Annual meeting of the American Society of Biomechanics (ASB 2013), University of Nebraska, Omaha, Nebraska, USA, 4-7 September 2013 (Poster presentation).
19th Congress of the European Society of Biomechanics (ESB 2013), University of Patras, Patras, Greece, 25-28 August 2013 (Podium presentation).
Awards and other Achievements
Fully funded PhD scholarship awarded by the Engineering and Physical Sciences Research Council (EPSRC).
Winner of judges' prize for best oral presentation given at Chemical engineering PhD symposium 2015. Symposium link.
2014 Chemical engineering departmental GTA of the year, awarded by the Faculty of Engineering, Imperial College London.
Selected as one of the only 6 finalists from more than 700 PhD students worldwide who submitted an abstract to 2014 American Society of Mechanical Engineers (ASME) doctoral level student paper competition (Theme: Cardiovascular Fluid Mechanics).
Science prize for the best performance by a first time A-Level student, awarded by Mander Portman Woodward Independent College.