@article{Bahou:2019:10.26434/chemrxiv.8267837.v2,
author = {Bahou, K and Braddock, DC and Meyer, AG and Savage, GP and Shi, Z},
doi = {10.26434/chemrxiv.8267837.v2},
title = {Relay Cross Metathesis for the Iterative Ascent of the Terpenoids},
url = {http://dx.doi.org/10.26434/chemrxiv.8267837.v2},
year = {2019}
}

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TY  - JOUR
AB  - <jats:p>We report the design and implementation of a relay crossmetathesis (ReXM) reaction for the ascent of the terpenoids in an iterative protocol. The method features the reaction of naturally occurring terpenoid building blocks – with preexisting trisubstituted olefins – which combine to construct a new trisubstituted olefin resulting in a five-carbon unit homologation. Subsequent functional group manipulation allows for the method to be repeated in aniterative fashion. The method is used for the synthesis of a diterpenebenzoate macrolide of biogenetic relevance to the bromophycolide family of natural products.</jats:p>
AU  - Bahou,K
AU  - Braddock,DC
AU  - Meyer,AG
AU  - Savage,GP
AU  - Shi,Z
DO  - 10.26434/chemrxiv.8267837.v2
PY  - 2019///
TI  - Relay Cross Metathesis for the Iterative Ascent of the Terpenoids
UR  - http://dx.doi.org/10.26434/chemrxiv.8267837.v2
ER  - 

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