Translational research addressing major challenges in neuroscience
Research in the Division of Neuroscience addresses mechanisms that underpin nervous system functions and diseases. Investigators in the Division are exploring these through combinations of neurophysiological, anatomical, molecular, cellular and computational approaches, using pre-clinical models and in clinical studies.
The integration of research groups of the UK DRI Centre at Imperial into the Division, as well as close collaborations with investigators who are part of the Division of Clinical Neurology, reflects the commitment of the Division of Neuroscience to combine mechanistic with translational research. Disease areas that currently are the focus for these more fundamental mechanistic investigations include Alzheimer’s disease and other late-life dementias, Parkinson’s disease, multiple sclerosis, glioblastomas, neurodevelopmental disorders and nerve and spinal cord injury.
Research areas and groups include:
- Neuronal circuitry and its plasticity in health and disease
- Cellular clocks in the brain
- Mitochondria neurobiology
- Neurodevelopmental biology
- Molecular and epigenetic mechanisms of ageing and neurodegeneration
- Molecular and cellular mechanisms of neuroinflammation
- Regenerative mechanisms in nerve and spinal cord injuries
- Neuro-oncology
- Gene therapy for brain diseases
- Bioinformatics for neurobiology
- Brain Tumour Research Centre
Research leads
Professor Stephen Gentleman
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Professor Stephen Gentleman
Head of Division and Professor of Neuropathology
Professor Simone di Giovanni
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Professor Simone di Giovanni
James W Harnett Chair in Restorative Neuroscience
Dr Kambiz Alavian
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Dr Kambiz Alavian
Reader in Neuroscience
Dr Samuel Barnes
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Dr Samuel Barnes
Associate Professor in Neural Plasticity
Dr Marco Brancaccio
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Dr Marco Brancaccio
Associate Professor
Dr Nurun Fancy
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Dr Nurun Fancy
Edmond and Lily Safra Research Fellow
Professor Richard Festenstein
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Professor Richard Festenstein
Clinical Professor of Molecular Medicine
Dr Kate Godfrey
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Dr Kate Godfrey
Imperial College Research Fellow
Dr Nir Grossman
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Dr Nir Grossman
Associate Professor in Neuroscience
Dr Nejc Haberman
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Dr Nejc Haberman
Imperial College Research Fellow
Professor Amin Hajitou
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Professor Amin Hajitou
Professor of Targeted Therapeutics
Dr Johanna Jackson
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Dr Johanna Jackson
Advanced Research Fellow
Dr Roberta Maggliozi
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Dr Roberta Maggliozi
Associate Professor
Dr Anna Mallach
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Dr Anna Mallach
Edmond and Lily Safra Research Fellow
Professor Nicholas Mazarakis
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Professor Nicholas Mazarakis
Chair MolBioMedicine and Head of Gene Therapy
Dr Raffaella Nativio
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Dr Raffaella Nativio
Assistant Professor in EpiAge and Neurodegeneration
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Dr Vincenzo De Paola
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Dr Vincenzo De Paola
Reader in Translational Neuroscience
Dr Kjara Pilch
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Dr Kjara Pilch
BBSRC Discovery Fellow
Dr Carola Radulescu
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Dr Carola Radulescu
Edmond and Lily Safra Research Fellow
Professor Richard Reynolds
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Professor Richard Reynolds
Professor of Cellular Neurobiology
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Professor Magdalena Sastre
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Professor Magdalena Sastre
Professor in Molecular Neuroscience
Dr Nathan Skene
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Dr Nathan Skene
Associate Professor and UK DRI Group Leader
Dr Nelofer Syed
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Dr Nelofer Syed
Senior Research Fellow
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Dr Naoto Watamuro
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Dr Naoto Watamuro
Edmond and Lily Safra Research Fellow