BibTex format
@article{Kim:2025:10.1038/s41467-025-61263-6,
author = {Kim, H and Hillson, NJ and Cho, B-K and Sung, BH and Lee, D-H and Kim, D-M and Oh, M-K and Chang, MW and Jin, Y-S and Rosser, SJ and Vegh, P and Fragkoudis, R and Le, Feuvre R and Scrutton, NS and Storch, M and Seong, W and Freemont, PS and Lee, S-G},
doi = {10.1038/s41467-025-61263-6},
journal = {Nature Communications},
title = {Abstraction hierarchy to define biofoundry workflows and operations for interoperable synthetic biology research and applications},
url = {http://dx.doi.org/10.1038/s41467-025-61263-6},
volume = {16},
year = {2025}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Lack of standardization in biofoundries limits the scalability and efficiency of synthetic biology research. Here, we propose an abstraction hierarchy that organizes biofoundry activities into four interoperable levels: Project, Service/Capability, Workflow, and Unit Operation, effectively streamlining the DesignBuildTestLearn (DBTL) cycle. This framework enables more modular, flexible, and automated experimental workflows. It improves communication between researchers and systems, supports reproducibility, and facilitates better integration of software tools and artificial intelligence. Our approach lays the foundation for a globally interoperable biofoundry network, advancing collaborative synthetic biology and accelerating innovation in response to scientific and societal challenges.
AU - Kim,H
AU - Hillson,NJ
AU - Cho,B-K
AU - Sung,BH
AU - Lee,D-H
AU - Kim,D-M
AU - Oh,M-K
AU - Chang,MW
AU - Jin,Y-S
AU - Rosser,SJ
AU - Vegh,P
AU - Fragkoudis,R
AU - Le,Feuvre R
AU - Scrutton,NS
AU - Storch,M
AU - Seong,W
AU - Freemont,PS
AU - Lee,S-G
DO - 10.1038/s41467-025-61263-6
PY - 2025///
SN - 2041-1723
TI - Abstraction hierarchy to define biofoundry workflows and operations for interoperable synthetic biology research and applications
T2 - Nature Communications
UR - http://dx.doi.org/10.1038/s41467-025-61263-6
UR - https://doi.org/10.1038/s41467-025-61263-6
VL - 16
ER -