Abstract
Over one billion people worldwide are affected by neurological disorders. For many patients with neurological disorders, drug therapy has failed or has proven to be inefficient. The lack of reliable diagnostics tools and the lack of safe and effective therapies are among the main challenges in treating neurological disorders. Intracranial EEG recording and electrical neuro-stimulation have been proven useful in diagnostics and treatment of a number of neurological disorders. Existing technologies do not satisfy many of the requirements for modern medical implants, such as the small form factor, number and spatial density of recording and stimulation sites, high accuracy of recording, complex in-implant signal processing for diagnostics and treatment, long lifetime, and high-data-rate wireless functionality. This seminar focuses on our latest results in the design of implantable integrated electronic circuits for automated monitoring, diagnostics and treatment of neurological disorders. A number of brain-interfacing microsystems developed at the University of Toronto will be presented. Examples of the presented microsystems include brain electrical activity monitors for automated neurological diagnostics and closed-loop neuro-stimulators for treating drug-resistant epilepsy.
Biography
Roman Genov received the B.S. degree in Electrical Engineering from Rochester Institute of Technology, NY in 1996 and the M.S.E. and Ph.D. degrees in Electrical and Computer Engineering from Johns Hopkins University, Baltimore, MD in 1998 and 2003 respectively. Dr. Genov held engineering positions at Atmel Corporation, Columbia, MD in 1995 and Xerox Corporation, Rochester, NY in 1996. He was a visiting researcher in the Laboratory of Intelligent Systems at Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland in 1998 and in the Center for Biological and Computational Learning at Massachusetts Institute of Technology, Cambridge, MA in 1999. He is presently a Professor in the Department of Electrical and Computer Engineering at the University of Toronto, Canada, where he is a member of Electronics Group and Biomedical Engineering Group and the Director of Intelligent Sensory Microsystems Laboratory. Dr. Genov’s research interests are primarily in analog integrated circuits and systems for energy-constrained biological, medical, and consumer sensory applications, such as implantable, wearable or disposable sensory microsystems, energy-efficient sensory signal processors and wireless sensors, including brain-chip interfaces, neuro-stimulators, image sensors, optical and electro-chemical DNA microarrays, and other biosensors. Dr. Genov is a co-recipient of Best Paper Award of IEEE Biomedical Circuits and Systems Conference, Best Student Paper Award of IEEE International Symposium on Circuits and Systems, Best Paper Award of IEEE Circuits and Systems Society Sensory Systems Technical Committee, Brian L. Barge Award for Excellence in Microsystems Integration, MEMSCAP Microsystems Design Award, DALSA Corporation Award for Excellence in Microsystems Innovation, and Canadian Institutes of Health Research Next Generation Award. He was a Technical Program Co-chair at IEEE Biomedical Circuits and Systems Conference. He was an Associate Editor of IEEE Transactions on Circuits and Systems-II: Express Briefs and IEEE Signal Processing Letters. Currently he is an Associate Editor of IEEE Transactions on Biomedical Circuits and Systems and member of IEEE International Solid-State Circuits Conference International Program Committee serving in Imagers, MEMS, Medical, and Displays (IMMD) Subcommittee.