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Big business is struggling to keep up with changes in technology, customer preferences and employee demands.  Start-ups are seen as innovative with an ear to the ground that quickly allows them to define and disrupt a market.  But can these entities, at opposite ends of the spectrum in terms of size, structure and formality usefully interact?  What can big business do to better understand the value of start-ups?  Does the traditional operating model of big business allow for innovation from outside of their corporate domain?  And what can start-ups do to be more accessible by corporates?  Based on his work with KPMG’s High Growth Technology Group Tim Kay will outline what is currently happening in the sector, the benefits and challenges.