Dr X Yun Xu, Reader in Biofluid Mechanics, Imperial College London, presents: ‘Image-based CFD modelling of coronary haemodynamics’ as part of the Department of Bioengineering’s Seminar Series.
Abstract: The coronary arteries are a common site of atherosclerosis, but haemodynamic patterns in coronary arteries differ significantly from other arteries owing to diastolic-dominant flow and cardiac-induced dynamic vessel motion. Although subject-specific flow and wall mechanics modelling has been applied to many disease-prone arterial regions by making use of in vivo anatomical and flow data, image-based coronary flow simulation is still a difficult challenge. This talk will describe the imaging techniques that can be used to provide the necessary geometry and boundary conditions for subject-specific coronary flow analysis as well as modelling challenges. Our recently obtained results on flow and mass transfer in the right coronary arteries based on detailed MRI and CT data will be presented. The effects of dynamic vessel motion and realistic flow waveforms on haemodynamic parameters will be discussed.
Biography: Dr. Yun Xu is a Reader in Biofluid Mechanics, Postgraduate Admissions Tutor and Coordinator of the Biomedical Engineering research focus area in the Department of Chemical Engineering at Imperial College London. She joined the Department of Chemical Engineering at Imperial College in 1998 as a Lecturer, and was promoted to Senior Lecturer in 2003 and Reader in 2005. She received her BSc and MSc degrees in Thermo-Fluids Engineering from Dalian University of Technology in China, and her Ph.D degree (1992) in the area of Mechanical Engineering from the City University, London, under the supervision of Professor Michael Collins. She is members of European Society of Biomechanics, European Mechanics Society and Biomedical Engineering Society. She is a Visiting Professor of Xi’an Jiaotong University, China. Her main research activities are in the field of biomedical engineering, with a special focus on fluid mechanics and transport processes in biological and physiological systems. She has published 6 book chapters and over 50 peer-reviewed journal articles on cardiovascular haemodynamics and wall mechanics particularly on image-based, subject-specific studies. She has supervised 25 PhD students (including past and present).
Light refreshments will be served in the Bagrit Centre, Level 1 Mechanical Engineering Building from 15.30.