heart

Dear Colleagues and Students,

NHLI will be holding a talk on Monday, 12 January 2026 from Professor Natasja de Groot, Erasmus University.

Talk Title: Intraoperative Mapping: From Mechanistic Insight to Clinical Impact

Time: 12:00 – 13:00 UK time

Location: Meeting room 427/428 4th Floor ICTEM, Hammersmith Campus, Du Cane Road W12 0NN

Introduction
Prof. Dr. Natasja MS de Groot, FEHRA works as senior cardiologist-electrophysiologist. She is appointed as full-time professor in the Erasmus Medical Center and the Technical University in Delft. She is also a Medical Delta Professor. She is experienced in device implantations and catheter ablation procedures with a variety of mapping/ablation technologies including remote magnetic/robotic navigation and a diversity of electro-anatomical mapping techniques. Main foci of her clinical work include: 1) catheter ablation of complex tachyarrhythmias such as post-operative tachyarrhythmias in patients with congenital heart disease, 2) catheter ablation in paediatric patients.
Field(s) of expertise

Her research projects are aimed at unravelling the pathophysiology of complex cardiac tachyarrhythmias, developing and testing developing novel diagnostic tools (in close collaboration with TU Delft) and therapies for cardiac arrhythmias. Main research topics are high resolution mapping studies of cardiac arrhythmias in particular atrial fibrillation, mechanisms of (post-operative) atrial fibrillation, dysrhythmias in patients with congenital heart disease and neuromodulation of atrial fibrillation. For this purpose, she has developed a unique way of recording and processing cardiac signals to perform mapping procedures.

Her innovative scientific contributions include:

  • discovery of novel mechanisms underlying persistence of atrial fibrillation
  • introduction endovascular mapping approach guiding ablative therapy of atrial tachyarrhythmias in patients with congenital heart disease
  • development of a novel, intra- operative epicardial mapping approach.
  • discovery of the role of Bachmann’s bundle in development of atrial tachyarrhythmias
  • performed worldwide the first high resolution mapping studies in pediatric patient
  • discovery conduction properties in pediatric patients with congenital heart disease

Getting here