About the speaker
David Sansom is Professor of Transplant Immunology at the UCL Institute for Immunity and Transplantation in London, based at the Royal Free Hospital. He did his BSc and PhD in Bristol, UK where he became interested in the susceptibility to autoimmunity, particularly rheumatoid arthritis. He held Senior Research Fellowships from Arthritis Research UK at the University of Bath, and the University of Birmingham before moving to University College London in 2013. In 2017 David became a Wellcome Trust Investigator.
David’s lab works on various aspects of human immune regulation in the area of T cell biology, with a particular focus on understanding the molecular and cellular biology that regulates CTLA-4 function. In 2011 he discovered a novel mechanism of CTLA-4 function termed “transendocytosis” providing a new perspective on CTLA-4 biology. Since moving to the Royal Free Hospital, he has been involved in the study of patients with heterozygous CTLA-4 defects, who develop a variety of autoimmune conditions due to impaired regulatory T cell function.
For further information, please contact Professor Steve Ley. s.ley@imperial.ac.uk
All are welcome to attend.