In this talk we address the following questions related to cell communication: how does communication between adjacent or distant cells emerge? How are the molecular signals in this communication issued, received and interpreted? Are these signals oriented and directed towards cells more predisposed to their reception? And the most important question, how can we influence this communication process? We intend to give an insight to these questions proposing some mathematical models about the transport, via microtubules, of cell communication signals and their orientation. We analyze the evolution and emergence of discontinuous interfaces or the existence of patterns and traveling wave type profiles in the signals. We contrast these results with biological experiments.