Organic Bioelectronic Interfaces Based on PEDOT:PSS-Based Crystalline Films, Microfibers, and Fibrillar Hydrogel
Myung-Han Yoon
School of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju 61005, South Korea
ABSTRACT
In this research, we developed organic bioelectronic interfaces based on highly crystalline poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) films or microfibers to overcome the trade-off between electrical/electrochemical performance and long-term stability in water. Crystalline PEDOT:PSS films exhibit excellent electrical/electrochemical/optical characteristics, long-term aqueous stability without film dissolution/delamination, and good viability for primarily cultured cardiomyocytes and neurons over several weeks. Furthermore, they are successfully employed for high-performance multi-electrode arrays (MEAs) to record and stimulate the electrophysiological activities of primarily cultured cardiomyocytes and chicken retinae tissues. In parallel, we developed crystalline PEDOT:PSS microfibers and PEDOT:PSS-incorporated hydrogel microfibers for single-strand wearable electrochemical transistors and 3-D neuronal network reconstruct, respectively.
References
[1] Seong-Min Kim, Chang-Hyun Kim, Youngseok Kim, Nara Kim, Won-June Lee, Eun-Hak Lee, Dokyun Kim, Sungjun Park, Kwanghee Lee1, Jonathan Rivnay, and Myung-Han Yoon* Nature Comm. 9, 3858 (2018) “Influence of PEDOT:PSS Crystallinity and Composition on Electrochemical Transistor Performance and Long-term Stability”
[2] Seong-Min Kim, Nara Kim, Youngseok Kim, Min-Seo Baik, Minsu Yoo, Dongyoon Kim, Won-June Lee, Dong-Hee Kang, Sohee Kim, Kwanghee Lee* and Myung-Han Yoon* NPG Asia Mater. 10, 255 (2018) “Solution-Processed Conductive Polymer Cellular Interfaces for Direct Electrical Stimulation and Recording”
[3] Youngseok Kim, Taekyung Lim, Chi-Hyeong Kim, Chang Su Yeo, Keumyoung Seo, Seong-Min Kim, Sang Yoon Park, Sanghyun Ju* and Myung-Han Yoon* NPG Asia Mater 10, 1086 (2018) “Single Strand Microfiber-Based Wearable Human Sweat Sensors with Channel Dimension Independent Performance”
BIOGRAPHY
Myung-Han Yoon received his B.S. (1999) in Chemistry and M.S. (2001) in Physical Chemistry at Seoul National University, South Korea. He studied “Organic Semiconductors and Dielectrics Based Thin Films Transistors” for his Ph.D. (2006) in Materials Chemistry with the guidance of Prof. Tobin J Marks at Northwestern University in US. In 2006, he moved to Department of Chemistry and Chemical Biology at Harvard University (Prof. Hongkun Park group) as a postdoctoral fellow and focused on neuronal electronic/fluidic interfaces. He joined School of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST) as a junior faculty member in 2010, and became promoted to an associate professor in 2015 and a full professor in 2018. He has been an advisory professor at LG Electronics since 2016. His research interest is “Developing Solution-Processable Functional Materials Based on Conducting Polymers, Sol-Gel Metal Oxides, Fibrillar Hydrogel for Printable Flexible Electronics and Bio-Electronic Interfaces”.