Publications
Results
- Showing results for:
- Reset all filters
Search results
-
Journal articleHerranz S, Rodríguez JM, Bussink HJ, et al., 2005,
Arrestin-related proteins mediate pH signaling in fungi
, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 102, Pages: 12141-12146, ISSN: 0027-8424- Author Web Link
- Cite
- Citations: 117
-
Journal articleBarnes PJ, Adcock IM, Ito K, 2005,
Histone deacetylase activity and COPD - Reply
, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 353, Pages: 528-529, ISSN: 0028-4793 -
Journal articleJames ES, Harney S, Wordsworth BP, et al., 2005,
PDCD1: a tissue-specific susceptibility locus for inherited inflammatory disorders.
, Genes Immun, Vol: 6, Pages: 430-437, ISSN: 1466-4879Variation in genes encoding costimulatory molecules expressed on lymphocytes has been expected to contribute to the genetic component of inflammatory disease, but only the gene encoding the inhibitory protein, CTLA-4, seems consistently to confer disease susceptibility. Studies in murine models implicate the inhibitory product of the pd1 gene, programmed death-1, in the maintenance of peripheral tolerance to self-antigens. We identify 22 single-nucleotide polymorphisms (SNPs) in the equivalent human gene, PDCD1, a number of which show significant associations with the specific immunoglobulin E response to grass allergens in atopic individuals. Stepwise analyses indicate that four of the disease-associated SNPs have independent effects. The two most common haplotypes show positive and negative associations but rarer haplotypes are also likely to be of influence. In a case-control study, multiple regression analysis of genotypic data implies that PDCD1 also confers susceptibility to rheumatoid arthritis. Along with work linking PDCD1 with susceptibility to another autoimmune condition, systemic lupus erythematosus, our data identify PDCD1 as a second immunomodulatory gene with pleiotropic effects in human disease. Genes encoding negative regulators may generally confer a significant fraction of the genetic risk associated with inherited inflammatory disorders.
-
Journal articleBidartondo MI, 2005,
The evolutionary ecology of myco-heterotrophy.
, New Phytologist, Vol: 167, Pages: 335-352, ISSN: 0028-646XNonphotosynthetic mycorrhizal plants have long attracted the curiosity of botanists and mycologists, and they have been a target for unabated controversy and speculation. In fact, these puzzling plants dominated the very beginnings of the field of mycorrhizal biology. However, only recently has the mycorrhizal biology of this diverse group of plants begun to be systematically unravelled, largely following a landmark Tansley review a decade ago and crucial developments in the field of molecular ecology. Here I explore our knowledge of these evolutionarily and ecologically diverse plant-fungal symbioses, highlighting areas where there has been significant progress. The focus is on what is arguably the best understood example, the monotropoid mycorrhizal symbiosis, and the overarching goal is to lay out the questions that remain to be answered about the biology of myco-heterotrophy and epiparasitism.
-
Journal articleBismarck A, Lee AF, Saraç AS, et al., 2005,
Electrocoating of carbon fibres:: A route for interface control in carbon fibre reinforced poly methylmethacrylate?
, COMPOSITES SCIENCE AND TECHNOLOGY, Vol: 65, Pages: 1564-1573, ISSN: 0266-3538- Author Web Link
- Cite
- Citations: 24
-
Journal articleBignell E, Negrete-Urtasun S, Calcagno AM, et al., 2005,
Virulence comparisons of <i>Aspergillus nidulans</i> mutants are confounded by the inflammatory response of p47<SUP><i>phox</i>-/-</SUP> mice
, INFECTION AND IMMUNITY, Vol: 73, Pages: 5204-5207, ISSN: 0019-9567- Author Web Link
- Cite
- Citations: 24
-
Conference paperMaeda K, Bismarck A, Briscoe BJ, 2005,
Mechanisms of scratching frictions and damage maps for rubber compounds
, 15th International Conference on Wear of Materials, Publisher: ELSEVIER SCIENCE SA, Pages: 651-660, ISSN: 0043-1648- Author Web Link
- Cite
- Citations: 23
-
Journal articleBrindicci C, Ito K, Resta O, et al., 2005,
Exhaled nitric oxide from lung periphery is increased in COPD
, EUROPEAN RESPIRATORY JOURNAL, Vol: 26, Pages: 52-59, ISSN: 0903-1936- Author Web Link
- Cite
- Citations: 162
-
Journal articleBismarck A, Pfaffernoschke M, Springer J, et al., 2005,
Polystyrene-grafted carbon fibers: Surface properties and adhesion to polystyrene
, JOURNAL OF THERMOPLASTIC COMPOSITE MATERIALS, Vol: 18, Pages: 307-331, ISSN: 0892-7057- Author Web Link
- Cite
- Citations: 12
-
Journal articleBoth M, Csukai M, Stumpf MPH, et al., 2005,
Gene expression profiles of <i>Blumeria graminis</i> indicate dynamic changes to primary metabolism during development of an obligate biotrophic pathogen
, PLANT CELL, Vol: 17, Pages: 2107-2122, ISSN: 1040-4651- Author Web Link
- Cite
- Citations: 115
This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.