The Section of Immunology of Infection brings together world-leading research teams across Imperial's campuses, focused on immune responses to infection, chronic disease and autoimmunity. Alongside fundamental research on immune system function, a strong emphasis is placed on the development of novel therapeutics and vaccines for the treatment and prevention of globally important infections. Our research spans a wide range of viral, bacterial, and parasite infections. Our researchers lead scientific programs and collaborations with European, African, South American and South-East Asian partners. Our translational vaccine and therapeutic research includes a program of first in human trials through to the evaluation of vaccine efficacy trials against HIV, tuberculosis and malaria by the Human Immunology Laboratory (HIL).
Research groups and Section leadership
Research areas and networks
A selection of the Section's key research areas and networks
- Imperial Network for Vaccine Research (INVaR)
- Human Immunology Lab (HIL)
- Mucosal Infection and Immunity
- Future Vaccine Manufacturing Research Hub
- Immune determinants of susceptibility and protection from infection
- Immunological regulation of infectious, inflammatory and autoimmune diseases
- Mathematical and bioinformatic analysis and modelling immune function
- Cell-mediated immunity and immunopathology.
- B cell memory, repertoire and antibody function
- The influence of co-infection on immune function, susceptibility and disease severity
- Vaccine research, development and translation
- Assessment of clinical vaccine trials (first in human to efficacy)
Section leadership
Professor John Tregoning
Section Head, Immunology of Infection
Prof John Tregoning is currently Professor of Vaccine Immunology at Imperial College London, where he has studied the immune responses to vaccination and respiratory infection for more than 25 years. His group is currently focusing on the immune response to RNA vaccination and RSV infection (exploring how the virus evolves under antibody pressure). John has written more than 90 peer-reviewed scientific articles and over 50 articles on scientific careers for Nature, Science and Times Higher Education. He is also the author of two books Live Forever? A Curious Scientist’s Guide to Wellness, Disease and Ageing and Infectious: Pathogens and how we fight them.
Research leads
Professor Becca Asquith
Professor Becca Asquith
Professor of Mathematical Immunology
Dr Margarita Dominguez-Villar
Dr Margarita Dominguez-Villar
Associate Professor in Immunology
Dr Daniel Gonçalves Carneiro
Dr Daniel Gonçalves Carneiro
Advanced Research Fellow
Professor Paul Kellam
Professor Paul Kellam
Professor of Virus Genomics
Dr Peter Kelleher
Dr Peter Kelleher
Clinical Associate Professor in Immunology
Dr Paul McKay
Dr Paul McKay
Advanced Research Fellow
Professor Robin Shattock
Professor Robin Shattock
Chair in Mucosal Infection and Immunity
Professor John Tregoning
Professor John Tregoning
Professor in Vaccine Immunology
General enquiries
Section Manager
Clare Soares
Laboratory Manager
Lesley Rawlinson
lesley.rawlinson@imperial.ac.uk
+44 (0)20 7594 5401
Laboratory Manager
Dominic Smith
+44 (0)7746 335 501