Pulmonary aspergillosis is a severe lung infection due to a green mould called Aspergillus fumigatus. We all inhale between 100 and 1000 Aspergillus spores daily, which can cause infections with mortality of around 40%, mostly in people with chronic lung diseases or weakened immune systems. There are estimated to be 4 million cases ofpulmonary aspergillosis globally per annum, but very little is known about rates in South-East Asia. Antifungal resistance to the main class of drugs used to treat these infections, the triazoles, is rising. Environmental resistance rates of up to 90% have been detected in Vietnam, and 30% in Thailand. Resistance has been shown to double mortality.

PI Lead : Prof. Leon Barron

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