OpenClinica V4.0

OpenClinica V4.0 is a fully GCP compliant, all in one platform, cloud-hosted system where the eCRFs are designed in-house by the ICTU Clinical Data Systems Team.

OpenClinica allows for a seamless and integrated user experience through the following modules - Enterprise (EDC), Participate (ePRO and eCOA), Randomize (IVRS and Supply), Insight (Reporting) hosted on the OpenClinica Cloud.

If requesting the use of OpenClinica, please contact cds_services@imperial.ac.uk

A recent article relating to OpenClinica, with input from CDS Team Leaders as well as the RIO, ePARCA-R and CURESPONSE study teams, can be found here.

Our Service benefits in OpenClinica V4.0

CDS Services
  • Easy and fast electronic capture through ultra-capable, user-friendly eCRFs
  • Real-time edit checks, skip logic and auto save of data input
  • Full in-built audit trail of data entry and changes
  • On-line data entry, monitoring and data sign-off which supports Clinical Data Management activities
  • Randomisation and Drug Supply Management, track drug kits and monitor inventory
  • Patient reported outcome (ePRO and eCOA)
  • Reporting of operational and clinical data in real time
  • Data extracts of the data for analyses
  • Disaster recovery provision
  • Supports compliance with legislation and regulatory guidance on clinical research management
CDS Services
  • Design, develop and build study specific eCRFs
  • System/ User acceptance testing of the study specific eCRFs
  • Release management of production version for web-based access at all study centres / sites for all study users
  • Role based training and access for site and sponsor users
  • User support for the duration of the study
  • Database maintenance, secure UK cloud hosted data storage and backup facilities
  • Database Lock and archive extract
  • Read only access to data after database lock

The Collaborations Section is currently being updated. 

If your request falls under one of the Therapeutic areas details for the relevant email can be found on the Therapeutic Area Contact Details Page.

For commercial sponsors

Visit our dedicated website for commercial sponsors interested in working with ICTU.

Temporary Clinical Trials Manager opportunity

We are looking for an experienced Clinical Trials Manager, preferably based in or near London, to join our supportive team on a temporary basis. 

Based within the Department of Surgery and Cancer with the Imperial Vascular Unit at St Mary’s Hospital and at the Imperial Clinical Trials Unit (ICTU) in White City, you will be working with the Imperial Vascular Unit to deliver a long-term study to perform a multicentre randomised controlled trial in patients with uncomplicated type B aortic dissection, to answer the question whether thoracic endovascular aortic repair (TEVAR) in the subacute phase in addition to best medical therapy is beneficial compared to standard treatment.

You will be responsible for all aspects of trial management, including close liaison with the Chief Investigator and Principal Investigators at other centres, management of the associated study and implementing and adapting established ICTU systems to ensure the trial is developed and conducted to the highest scientific and regulatory standards.

A Bachelor’s degree or equivalent in a biomedical/scientific field or related field and proven clinical trial/project management and monitoring experience gained in multi-centre, randomised trials is essential. You will need to show strong leadership and motivational skills as well as effective communication, organisational and time management skills.

This full-time temporary post is available from September 2026 and is offered for 3 months. Travel is expected between the Imperial College campuses and research sites.

For more information, please review the EARNEST TM (Temp) Job Description Aug 2026.pdf.

To apply for this position, please send your CV and covering letter to t.sasikaran@imperial.ac.uk  (Operations Manager, ICTU).

Advert closing date: Tuesday, 25 August 2026

Interview date: Friday, 28 August 2026

Start date: ASAP, available from September

If you are interested, get in touch, we would love to hear from you!