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  • Journal article
    Baciu M, Sebai S C, Ces O, Mulet X, Clarke J A, Shearman G C, Law R V, Templer R H, Plisson C, Parker C A, Gee Aet al., 2006,

    Degradative Transport of Cationic Amphiphilic Drugs Across Phospholipid Bilayers

    , Phil. Trans . R. Soc., Vol: 364, Pages: 2597-2614
  • Journal article
    Squires A, Templer R H, Seddon J M, Woenckhaus J, Winter R, Theyencheri N, Finet Set al., 2005,

    Kinetics and mechanism of the interconversion of inverse bicontinuous cubic mesophases

    , Phys. Rev. E, Vol: 72, Pages: 011502-1-011502-16
  • Conference paper
    Sushko ML, Seddon JM, Templer RH, 2004,

    Influence of electrostatic interactions on the history dependent rheology of surfactant hexagonal phases

    , 19th International Liquid Crystal Conference, Publisher: TAYLOR & FRANCIS LTD, Pages: 9-20, ISSN: 1542-1406
  • Conference paper
    Seddon JM, Ces O, Templer RH, Mannock DA, McElhaney RNet al., 2003,

    Structure and phase behaviour of synthetic glycolipids

    , 2nd Anglo-Japanese Seminar on Liquid Crystals, Publisher: TAYLOR & FRANCIS LTD, Pages: 313-320, ISSN: 1542-1406
  • Journal article
    Sennoga C, Heron A, Seddon JM, Templer RH, Hankamer Bet al., 2003,

    Membrane-protein crystallization in cubo: temperature-dependent phase behaviour of monoolein-detergent mixtures

    , Acta Crystallographica D Biological Crystallography, Vol: 59, Pages: 239-246

    The lipidic cubic phase of monoolein has proved to be a matrix well suited to the production of three-dimensional crystals of membrane proteins. It consists of a single continuous bilayer, which is contorted in three-dimensional space and separates two distinct water channels. It has previously been proposed that on the addition of precipitants, membrane proteins embedded in the cubic phase migrate through the matrix to nucleation sites and that this process is dependent upon the stability of the lipidic cubic phase. Here, the effect of detergent type (C(8)-C(12) glucosides, C(8)-C(12) maltosides and C(7) thioglucoside) and concentration (1-3x the critical micelle concentration; CMC) on cubic phase stability are reported in the form of the temperature-dependent phase behaviour (268-313 K) in 40% aqueous solution. The results are tabulated to show the best monoolein (MO)-detergent mixtures, mixing temperatures and crystallization temperatures identified. Monoolein-detergent mixtures suited for low-temperature in cubo crystallization of temperature-sensitive proteins are also reported for the first time. These mixtures can be prepared at low temperatures (mixed at <or=288 K) and remain stable at 277 K for a period of at least one Month. They include MO-heptyl thioglucoside (1x and 3x CMC), MO-nonyl glucoside (3x CMC), MO-octyl maltoside (3x CMC), MO-nonyl maltoside (1x CMC) and MO-decyl maltoside (1x CMC).

  • Conference paper
    Seddon JM, Squires A, Ces O, Templer RH, Woenckhaus J, Winter Ret al., 2003,

    Time-resolved diffraction studies of inverse cubic phases and phase transitions of lipids

    , Amsterdam, Meeting on self-assembly - the future, Massa Marittima, Italy, 2002, Publisher: I O S Press, Pages: 212-221
  • Journal article
    Squires AM, Templer RH, Seddon JM, Woenckhaus J, Winter R, Finet S, Theyencheri Net al., 2002,

    Kinetics and mechanism of the lamellar to gyroid inverse bicontinuous cubic phase transition

    , LANGMUIR, Vol: 18, Pages: 7384-7392, ISSN: 0743-7463
  • Journal article
    Sushko ML, Seddon JM, Templer RH, 2002,

    History-dependent rheology of a surfactant hexagonal phase

    , PHYSICAL REVIEW E, Vol: 65, ISSN: 2470-0045
  • Conference paper
    Squires AM, Seddon JM, Templer RH, 2002,

    Models and measurements on the monolayer bending energy of inverse lyotropic mesophases

    , Cambridge, 1st annual international conference on biophysical chemistry, Imperial College of Science & Technology London, London, England, 19 - 21 September 2001, Publisher: Royal Society of Chemistry, Pages: 177-190
  • Conference paper
    Ces O, Seddon JM, Templer RH, Mannock DA, McElhaney RNet al., 2002,

    Differential scanning calorimetry and x-ray diffraction studies of glycolipid membranes

    , Cambridge, 1st annual international conference on biophysical chemistry, Imperial College of Science & Technology London, London, England, 19 - 21 September 2001, Publisher: Royal Society of Chemistry, Pages: 267-276
  • Conference paper
    Sennoga C, Hankamer B, Heron A, Seddon JM, Barber J, Templer RHet al., 2002,

    Morphological aspects of in cubo membrane protein crystallisation

    , Cambridge, 1st annual international conference on biophysical chemistry, Imperial College of Science & Technology London, London, England, 19 - 21 September 2001, Publisher: Royal Society of Chemistry, Pages: 221-236
  • Journal article
    Squires A, Templer RH, Ces O, Gabke A, Woenckhaus J, Seddon JMet al., 2000,

    Kinetics of lyotropic phase transitions involving the inverse bicontinous cubic phases

    , Langmuir, Vol: 16, Pages: 3578-3582, ISSN: 0743-7463
  • Journal article
    Squires A, Templer RH, Ces O, Gabke A, Woenckhaus J, Seddon JMet al., 2000,

    Kinetics of lyotropic phase transitions involving the inverse bicontinous cubic phases

    , Langmuir, Vol: 16, Pages: 3578-3582, ISSN: 0743-7463
  • Journal article
    Vacklin H, Khoo BJ, Madan KH, Seddon JM, Templer RHet al., 2000,

    The bending elasticity of 1-monoolein upon relief of packing stress

    , Langmuir, Vol: 16, Pages: 4741-4748, ISSN: 0743-7463
  • Journal article
    Winter R, Erbes J, Templer RH, Seddon JM, Syrykh A, Warrender NA, Rapp Get al., 1999,

    Inverse bicontinuous cubic phases in fatty acid/phosphatidylcholine mixtures: the effects of pressure and lipid composition

    , Physical Chemistry Chemical Physics, Vol: 1, Pages: 887-893, ISSN: 1463-9076
  • Journal article
    Templer RH, Seddon JM, Warrender NA, Syrykh A, Huang Z, Winter R, Erbes Jet al., 1998,

    Inverse bicontinuous cubic phases in 2:1 fatty acid phosphatidylcholine mixtures. The effects of chain length, hydration, and temperature

    , Journal of Physical Chemistry B, Vol: 102, Pages: 7251-7261, ISSN: 1089-5647
  • Journal article
    Templer RH, Khoo BJ, Seddon JM, 1998,

    Gaussian curvature modulus of an amphiphilic monolayer

    , Langmuir, Vol: 14, Pages: 7427-7434, ISSN: 0743-7463
  • Journal article
    Templer RH, Seddon JM, Duesing PM, Winter R, Erbes Jet al., 1998,

    Modeling the phase behavior of the inverse hexagonal and inverse bicontinuous cubic phases in 2:1 fatty acid phosphatidylcholine mixtures

    , Journal of Physical Chemistry B, Vol: 102, Pages: 7262-7271, ISSN: 1089-5647
  • Journal article
    Seddon JM, Templer RH, Warrender NA, Huang Z, Cevc G, Marsh Det al., 1997,

    Phosphatidylcholine fatty acid membranes: Effects of headgroup hydration on the phase behaviour and structural parameters of the gel and inverse hexagonal (H-II) phases

    , Biochimica et Biophysica Acta-Biomembranes, Vol: 1327, Pages: 131-147, ISSN: 0005-2736
  • Journal article
    Raimondi ME, Maschmeyer T, Templer RH, Seddon JMet al., 1997,

    Synthesis of direct templated aligned mesoporous silica coatings within capillaries

    , Chemical Communications, Pages: 1843-1844, ISSN: 1359-7345
  • Journal article
    Sakya P, Seddon JM, Templer RH, Mirkin RJ, Tiddy GJTet al., 1997,

    Micellar cubic phases and their structural relationships: The nonionic surfactant system C12EO12/water

    , Langmuir, Vol: 13, Pages: 3706-3714, ISSN: 0743-7463
  • Journal article
    Duesing PM, Seddon JM, Templer RH, Mannock DAet al., 1997,

    Pressure effects on lamellar and inverse curved phases of fully hydrated dialkyl phosphatidylethanolamines and beta-D-xylopyranosyl- sn-glycerols

    , Langmuir, Vol: 13, Pages: 2655-2664, ISSN: 0743-7463
  • Journal article
    Duesing PM, Templer RH, Seddon JM, 1997,

    Quantifying packing frustration energy in inverse lyotropic mesophases

    , Langmuir, Vol: 13, Pages: 351-359, ISSN: 0743-7463
  • Journal article
    Duesing PM, Templer RH, Seddon JM, 1996,

    A pressure- and temperature-controlled sample cell for the structural investigation of lyotropic liquid crystals using a small-angle x-ray diffraction line source

    , Review of Scientific Instruments, Vol: 67, Pages: 4228-4234, ISSN: 0034-6748
  • Journal article
    Huang Z, Seddon JM, Templer RH, 1996,

    An inverse micellar Fd3m cubic phase formed by hydrated phosphatidylcholine/fatty alcohol mixtures

    , Chemistry and Physics of Lipids, Vol: 82, Pages: 53-61, ISSN: 0009-3084
  • Journal article
    Seddon JM, Zeb N, Templer RH, McElhaney RN, Mannock DAet al., 1996,

    An Fd3m lyotropic cubic phase in a binary glycolipid/water system

    , Langmuir, Vol: 12, Pages: 5250-5253, ISSN: 0743-7463
  • Journal article
    TEMPLER RH, TURNER DC, HARPER P, SEDDON JMet al., 1995,

    CORRECTIONS TO SOME MODELS OF THE CURVATURE ELASTIC ENERGY OF INVERSE BICONTINUOUS CUBIC PHASES

    , JOURNAL DE PHYSIQUE II, Vol: 5, Pages: 1053-1065, ISSN: 1155-4312
  • Book chapter
    Seddon JM, Templer RH, 1995,

    Polymorphism of Lipid-Water Systems

    , Handbook of Biological Physics: Structure and Dynamics of Membranes, Editors: Hoff, Lipowsky, Sackmann, Hoff, Lipowsky, Sackmann, Amsterdam, Publisher: Elsevier SPC, Pages: 97-160
  • Journal article
    SAKYA P, SEDDON JM, TEMPLER RH, 1994,

    LYOTROPIC PHASE-BEHAVIOR OF N-OCTYL-1-O-BETA-D-GLUCOPYRANOSIDE AND ITS THIO DERIVATIVE N-OCTYL-1-S-BETA-D-GLUCOPYRANOSIDE

    , JOURNAL DE PHYSIQUE II, Vol: 4, Pages: 1311-1331, ISSN: 1155-4312
  • Conference paper
    TEMPLER RH, SEDDON JM, WARRENDER NA, 1994,

    MEASURING THE ELASTIC PARAMETERS FOR INVERSE BICONTINUOUS CUBIC PHASES

    , International Workshop on Membrane Structure Dynamics and Interactions via Neutron and X-ray Scattering, Publisher: ELSEVIER SCIENCE BV, Pages: 1-12, ISSN: 0301-4622
  • Journal article
    SEDDON JM, TEMPLER RH, 1993,

    CUBIC PHASES OF SELF-ASSEMBLED AMPHIPHILIC AGGREGATES

    , PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, Vol: 344, Pages: 377-401, ISSN: 0962-8428
  • Conference paper
    HARRISON A, LANE LC, TEMPLER RH, SEDDON JMet al., 1991,

    MECHANISM OF CHARGE STORAGE AND LUMINESCENCE STIMULATION IN BAFBR-RE PHOSPHORS

    , 2ND LONDON CONF ON POSITION-SENSITVE DETECTORS, Publisher: ELSEVIER SCIENCE BV, Pages: 220-223, ISSN: 0168-9002
  • Conference paper
    TEMPLER RH, WARRENDER NA, SEDDON JM, DAVIS JM, HARRISON Aet al., 1991,

    THE INTRINSIC RESOLUTION OF X-RAY-IMAGING PLATES

    , 2ND LONDON CONF ON POSITION-SENSITVE DETECTORS, Publisher: ELSEVIER SCIENCE BV, Pages: 232-235, ISSN: 0168-9002
  • Journal article
    SEDDON J, TEMPLER R, 1991,

    LIQUID-CRYSTALS AND THE LIVING CELL

    , NEW SCIENTIST, Vol: 130, Pages: 45-49, ISSN: 0262-4079

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