In this section
@article{Benton:2023:10.3389/fbioe.2023.1128528,
author = {Benton, A and Amiri, P and Henson, DP and Sivapuratharasu, B and McGregor, AH and Bull, A},
doi = {10.3389/fbioe.2023.1128528},
journal = {Frontiers in Bioengineering and Biotechnology},
pages = {1--10},
title = {Characterization of muscle recruitment during gait of bilateral transfemoral and through-knee persons with limb loss},
url = {http://dx.doi.org/10.3389/fbioe.2023.1128528},
volume = {11},
year = {2023}
}
TY - JOUR
AB - Introduction: Due to loss in musculoskeletal capacity, there is an increased burden on the residual limbs of bilateral transfemoral and through-knee persons with limb loss. This reduced capacity is associated with an increased cost of walking that is detrimental to functionality. Compensatory gait strategies are adopted by this population. However, how these strategies relate to specific muscle recruitment is not known. The primary aim of this study is to characterize muscle recruitment during gait of this population. The secondary aim is to assess whether the measured kinematics can be actuated when the endurance of specific muscles is reduced and if this is the case, which alternative muscles facilitate this.Methods: 3D gait data and high-resolution magnetic resonance images were acquired from six bilateral transfemoral and through-knee persons with limb loss. Subject-specific anatomical muscle models were developed for each participant, and a validated musculoskeletal model was used to quantify muscle forces in two conditions: during normal gait (baseline) and when muscles, which were identified as functioning above a “healthy” level at baseline, have a reduced magnitude of maximum force capacity (reduced endurance simulation). To test the hypothesis that there are differences in muscle forces between the baseline trials and the simulations with reduced muscular endurance, a Bonferroni corrected two-way ANOVA with repeated measures was completed between the two states.Results: The baseline analysis showed that the hip flexors experience relatively high muscle activations during gait. The reduced endurance simulation found two scenarios. First, for 5 out of the 12 simulations, the baseline kinematics could not be reproduced with the reduced muscular capacity. Second, for 7 out of 12 cases where the baseline kinematics were achieved, this was possible with compensatory increased activation of some muscles with similar functions (p ≤ 0.003).Discussion
AU - Benton,A
AU - Amiri,P
AU - Henson,DP
AU - Sivapuratharasu,B
AU - McGregor,AH
AU - Bull,A
DO - 10.3389/fbioe.2023.1128528
EP - 10
PY - 2023///
SN - 2296-4185
SP - 1
TI - Characterization of muscle recruitment during gait of bilateral transfemoral and through-knee persons with limb loss
T2 - Frontiers in Bioengineering and Biotechnology
UR - http://dx.doi.org/10.3389/fbioe.2023.1128528
UR - https://www.frontiersin.org/articles/10.3389/fbioe.2023.1128528/full
VL - 11
ER -