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  • Journal article
    Cowell I, O'Sullivan P, O'Sullivan K, Poyton R, McGregor A, Murtagh Get al., 2019,

    The Perspectives of physiotherapists on managing non-specific low back pain following a training programme in Cognitive Functional Therapy: a qualitative study

    , Musculoskeletal Care, Vol: 17, Pages: 79-90, ISSN: 1478-2189

    Background: It has long been acknowledged that nonspecific chronic low back pain (NSCLBP) is associated with a complex combination of biopsychosocial (BPS) factors, and recent guidelines advocate that the management of back pain should reflect this multidimensional complexity. Cognitive functional therapy (CFT) is a behaviourally oriented intervention that targets patients' individual BPS profiles. Although the efficacy of CFT has been demonstrated in primary care, little evidence exists about the training requirements of this approach.Methods: Qualitative semistructured interviews were conducted with 10 physiotherapists working in primary care, who had undergone a formal training programme in CFT. A purposive sampling method was employed to seek the broadest perspectives. Thematic analysis was used to analyse the interview transcripts and capture the emergent themes.Results: Five main themes emerged: (i) the learning challenge; (ii) self‐reported changes in confidence; (iii) self‐reported changes in communication practice; (iv) self‐reported changes in attitudes and understanding; (v) the physiotherapists felt that CFT was more effective than their usual approach for NSCLBP but identified barriers to successful implementation, which included a lack of time and difficulties in engaging patients with strong biomedical beliefs.Conclusions: The study suggested that training in CFT has the capacity to produce self‐reported changes in physiotherapists' attitudes, confidence and practice. The provision of such training has implications in terms of time and costs; however, this this may be warranted, given the physiotherapists' strong allegiance to the approach compared with their usual practice.

  • Journal article
    Oosthuizen CR, Takahashi T, Rogan DM, Hans Snyckers C, Peter Vermaak D, Griffith Jones G, Porteous A, Maposa I, Pandit Het al., 2019,

    The Knee Osteoarthritis Grading System (KOGS) for arthroplasty

    , The Journal of Arthroplasty, Vol: 34, Pages: 450-455, ISSN: 0883-5403

    BackgroundThe aim of this study is to validate the Knee Osteoarthritis Grading system (KOGS) of progressive osteoarthritic (OA) degeneration for the Tri-compartmental knee. This system defines the site and severity of OA to determine a specific knee replacement.MethodsThe radiographic sequence for KOGS includes standing coronal (antero-posterior), lateral, 30° skyline patella, 15° and 45° Rosenberg and stress views in 20° of flexion.Cohen’s Kappa and related agreement statistical methods were used to assess the level of concordance of the seven evaluators between A and B cohorts for each evaluator and also against the actual arthroplasty used. Sensitivity and specificity was also assessed for the KOGS in identifying true partial knee replacements (PKR) and total knee replacements (TKR) as decided from the cohort A evaluations.ResultsFrom a cohort of 330 patients who were included in the study, 71 (22.5%) underwent a TKR procedure, 258 (78.2%) a PKR and 1 (0.3%) was neither a TKR nor PKR. KOGS was able to identify true PKRs (sensitivity) in the range of 92.2% to 98.5% across all the different evaluators. The KOGS method was able to identify a PKR or a TKR with an accuracy ranging from 92% to 98.8% across all different evaluators.The surgical results after 20 months are at least comparable with the expected average in the academic literature.ConclusionThe KOGS classification provides a reliable and accurate tool to assess suitability of an individual patient for undergoing partial or total knee replacement.

  • Book
    Sugand K, Berry M, Yusuf I, Bird C, Janjua A, Thrumurthy Set al., 2019,

    Oxford Handbook for Medical School

    , Publisher: Oxford University Press, USA, ISBN: 9780199681907

    This handbook includes quick-access summaries covering the crucial information for your preclinical years and for each clinical specialty.

  • Conference paper
    Kaufmann J, Phillips A, McGregor A, 2019,

    Investigating bone health in lower-limb amputees

    , ISB/ASB 2019
  • Journal article
    Jones GG, Clarke S, Jaere M, Cobb JPet al., 2019,

    Failed high tibial osteotomy: A joint preserving alternative to total knee arthroplasty

    , Orthopaedics and Traumatology: Surgery and Research, Vol: 105, Pages: 85-88, ISSN: 1877-0568

    High tibial osteotomy is an attractive treatment option for young active patients wishing to return to high-level activities. However, it is not considered a long-term solution, with 30% revised at ten years. Currently, the only revision option is a total knee arthroplasty, a procedure that might not deliver the functional level expected by these highly active patients. This paper describes a novel joint preserving approach to HTO revision, using assistive technology, in the form of 3D printed guides, to reverse the osteotomy and simultaneously perform a unicompartmental knee replacement. The indications and planning aims for this procedure are discussed, and the preliminary results in four patients presented.

  • Journal article
    Jones GG, Clarke S, Jaere M, Cobb JPet al., 2019,

    Prothèse unicompartimentaire et désostéotomie pour échec d’ostéotomie tibiale : une alternative chirurgicale à l’arthroplastie totale de genouFailed high tibial osteotomy: A joint preserving alternative to total knee arthroplasty

    , Revue de Chirurgie Orthopedique et Traumatologique, Vol: 105, Pages: 41-41, ISSN: 1877-0517

    High tibial osteotomy is an attractive treatment option for young active patients wishing to return to high level activities. However, it is not considered a long-term solution, with 30% revised at ten years. Currently, the only revision option is a total knee arthroplasty, a procedure that might not deliver the functional level expected by these highly active patients. This paper describes a novel joint preserving approach to HTO revision, using assistive technology, in the form of 3D printed guides, to reverse the osteotomy and simultaneously perform a unicompartmental knee replacement. The indications and planning aims for this procedure are discussed, and the preliminary results in four patients presented. Level of evidence: IV.

  • Journal article
    Reznikov N, Boughton OR, Ghouse S, Weston AE, Collinson L, Blunn GW, Jeffers JRT, Cobb JP, Stevens MMet al., 2019,

    Individual response variations in scaffold-guided bone regeneration are determined by independent strain- and injury-induced mechanisms

    , BIOMATERIALS, Vol: 194, Pages: 183-194, ISSN: 0142-9612
  • Journal article
    Riyiere C, Harman C, Leong A, Cobb J, Maillot Cet al., 2019,

    Kinematic alignment technique for medial OXFORD UKA: An in-silico study

    , ORTHOPAEDICS & TRAUMATOLOGY-SURGERY & RESEARCH, Vol: 105, Pages: 63-70, ISSN: 1877-0568
  • Journal article
    Sperry MM, Phillips ATM, McGregor AH, 2019,

    Lower back pain and healthy subjects exhibit distinct lower limb perturbation response strategies: a preliminary study

    , Journal of Back and Musculoskeletal Rehabilitation, Vol: 32, Pages: 27-35, ISSN: 1053-8127

    BACKGROUND: It is hypothesized that inherent differences in movement strategies exist between control subjects and those with a history of lower back pain (LBP). Previous motion analysis studies focus primarily on tracking spinal movements, neglecting the connection between the lower limbs and spinal function. Lack of knowledge surrounding the functional implications of LBP may explain the diversity in success from general treatments currently offered to LBP patients. OBJECTIVE: This pilot study evaluated the response of healthy controls and individuals with a history of LBP (hLBP) to a postural disturbance. METHODS: Volunteers (n= 26) were asked to maintain standing balance in response to repeated balance disturbances delivered via a perturbation platform while both kinematic and electromyographic data were recorded from the trunk, pelvis, and lower limb. RESULTS: The healthy cohort utilized an upper body-focused strategy for balance control, with substantial activation of the external oblique muscles. The hLBP cohort implemented a lower limb-focused strategy, relying on activation of the semitendinosus and soleus muscles. No significant differences in joint range of motion were identified. CONCLUSIONS: These findings suggest that particular reactive movement patterns may indicate muscular deficits in subjects with hLBP. Identification of these deficits may aid in developing specific rehabilitation programs to prevent future LBP recurrence.

  • Journal article
    Wang H, Sugand K, Newman S, Jones G, Cobb J, Auvinet Eet al., 2019,

    Are multiple views superior to a single view when teaching hip surgery? A single-blinded randomized controlled trial of technical skill acquisition

    , PLoS ONE, Vol: 14, ISSN: 1932-6203

    s Metrics Comments Media Coverage Abstract Introduction Materials and methods Results Discussion Conclusion Supporting information References Reader Comments (0) Media Coverage (0) FiguresAbstractPurposeSurgical education videos currently all use a single point of view (POV) with the trainee locked onto a fixed viewpoint, which may not deliver sufficient information for complex procedures. We developed a novel multiple POV video system and evaluated its training outcome compared with traditional single POV.MethodsWe filmed a hip resurfacing procedure performed by an expert attending using 8 cameras in theatre. 30 medical students were randomly and equally allocated to learn the procedure using the multiple POV (experiment group [EG]) versus single POV system (control group [CG]). Participants advanced a pin into the femoral head as demonstrated in the video. We measured the drilling trajectories and compared it with pre-operative plan to evaluate distance of the pin insertion and angular deviations. Two orthopedic attendings expertly evaluated the participants’ performance using a modified global rating scale (GRS). There was a pre-video knowledge test that was repeated post-simulation alongside a Likert-scale questionnaire.ResultsThe angular deviation of the pin in EG was significantly less by 29% compared to CG (p = 0.037), with no significant difference in the entry point’s distance between groups (p = 0.204). The GRS scores for EG were 3.5% higher than CG (p = 0.046). There was a 32% higher overall knowledge test score (p<0.001) and 21% improved Likert-scale questionnaire score (p = 0.002) after video-learning in EG than CG, albeit no significant difference in the knowledge test score before video-learning (p = 0.721).ConclusionThe novel multiple POV provided significant objective and subjective advantages over single POV for acquisition of technical skills in hip surgery.

  • Journal article
    Doyle R, Boughton O, Plant D, Desoutter G, Cobb JP, Jeffers JRTet al., 2019,

    An in vitro model of impaction during hip arthroplasty

    , JOURNAL OF BIOMECHANICS, Vol: 82, Pages: 220-227, ISSN: 0021-9290
  • Book chapter
    Iranpour F, Aframian A, Cobb JP, 2019,

    Patellofemoral Osteoarthritis: Patellofemoral Arthroplasty

    , Disorders of the Patellofemoral Joint Diagnosis and Management, Pages: 129-134

    Patellofemoral osteoarthritis is common in older people and those with risk factors including trochlear dysplasia and patellofemoral instability. Patellofemoral arthroplasty (PFA) is indicated in such patients and has the advantage of leaving the remaining structures of the knee intact, including the native tibiofemoral joint surfaces and cruciate ligaments. The design of PFA has evolved from inlay designs to onlay designs which are either symmetrical or asymmetrical, to match the native trochlea. Long-term survival of currently used implants is suboptimal, with the largest series of the most commonly used implant reporting a 10-year survival of 77.3% at 10 years, with most patients being revised for progression of disease. Improvements in our understanding of the indications for PFA together with improvements in the design of instruments and instrumentation have the potential to improve the survival of PFA in the future, allowing more people to benefit from the advantages it confers over total knee arthroplasty (TKA).

  • Book chapter
    Rodríguez-Merchán EC, Liddle AD, 2019,

    Patellofemoral Osteoarthritis: Partial Lateral Patellar Facetectomy

    , Disorders of the Patellofemoral Joint Diagnosis and Management, Pages: 123-127

    Partial lateral facetectomy is a relatively easy and efficacious surgical treatment for middle-aged to elderly active patients with isolated lateral patellofemoral osteoarthritis (OA) who require pain relief and maintenance of level of activity but who wish to avoid arthroplasty. It can be performed arthroscopically or open. The indications are isolated patellofemoral OA in patients with an overhanging lateral facet of the patella with anterolateral knee pain and lack of response to conservative treatment. A satisfactory outcome after lateral patellar facetectomy for isolated patellofemoral OA can be foreseen in about half of the cases at 10 years follow-up; patellofemoral arthroplasty (PFA) or total knee arthroplasty (TKA) may be performed with no special considerations in patients who do not achieve adequate pain relief following partial lateral facetectomy.

  • Journal article
    Rodríguez-Merchán EC, Liddle AD, 2019,

    Preface

    , Disorders of the Patellofemoral Joint Diagnosis and Management, Pages: v-vi
  • Book chapter
    Rodríguez-Merchán EC, Encinas-Ullán CA, Liddle AD, 2019,

    Risk Factors and Demographics for Recurrent Lateral Dislocation of the Patella in Adults

    , Disorders of the Patellofemoral Joint Diagnosis and Management, Pages: 59-65

    The management of acute dislocation of the patella is focused on the avoidance of long term instability. In the absence of surgery, around one third of the up to 77 traumatic knee dislocations which occur per 100, 000 persons per year go on to chronic instability. Predictors include demographic factors (most importantly, the youth of the patient) and morphological factors. Those who go on to chronic instability generally have at least two morphological risk factors; the most important of these are trochlear dysplasia, patella alta, increased tibial tubercle-trochlear groove distance and generalised malalignment or malrotation of the lower limb.

  • Book chapter
    Liddle AD, Rodríguez-Merchán EC, 2019,

    Patellofemoral Instability: Lateral Release

    , Disorders of the Patellofemoral Joint Diagnosis and Management, Pages: 89-94

    Lateral retinacular release has historically been a popular procedure for the treatment of recurrent patellar instability in adolescents and adults. However, as our understanding of the anatomy, physiology and pathology of patellar instability has increased, it has fallen out of favour. Current management of patellar instability has focused on treating the pathoanatomy involved, in an approach individualized to the patient. Currently, lateral release is used as an adjunct to other surgical procedures for instability, with other indications including isolated retinacular pain or symptomatic bipartite patella. In this chapter, the techniques, indications, results and complications of lateral release are discussed.

  • Book
    Rodríguez-Merchán EC, Liddle AD, 2019,

    Disorders of the Patellofemoral Joint: Diagnosis and Management

    This state-of-the-art book provides a comprehensive overview of the most common patellofemoral joint problems. Utilizing the latest evidence, it guides readers through prevention, diagnosis and treatment for both adult and paediatric patients. After discussing clinical examination and diagnosis, it explores topics such as acute and recurrent dislocation of the patella, cartilage defects of the joint, patellofemoral instability and patellofemoral osteoarthritis. The book also features a chapter on conservative strategies, including physical medicine and rehabilitation. Research is moving quickly in this field, and as such there is a growing need for consensus documents: written by leading experts, this comprehensive book is a valuable resource for orthopaedic surgeons, knee specialists and sports medicine ones, and is also of great interest to physiatrists, physical therapists and all healthcare workers involved in the care of these patients.

  • Journal article
    Maillot C, Leong A, Harman C, Morelli A, Mospan R, Cobb J, Riviere Cet al., 2019,

    Poor relationship between frontal tibiofemoral and trochlear anatomic parameters: Implications for designing a trochlea for kinematic alignment

    , KNEE, Vol: 26, Pages: 106-114, ISSN: 0968-0160
  • Journal article
    Papi E, Bull A, McGregor A, 2019,

    Spinal segments do not move together predictably during daily activities

    , Gait and Posture, Vol: 67, Pages: 277-283, ISSN: 0966-6362

    Background: Considering the thoracic, lumbar spine or whole spine as rigid segments has been the norm until recent studies highlighted the importance of more detailed modelling. A better understanding of the requirement for spine multi-segmental analysis could guide planning of future studies and avoid missing clinically-relevant information.Research question: This study aims to assess the correlation between adjacent spine segments movement thereby evaluating segmental redundancy in both healthy and participants with low back pain (LBP).Methods: A 3D motion capture system tracked the movement of upper and lower thoracic and lumbar spine segments in twenty healthy and twenty participants with LBP. Tasks performed included walking, sit-to-stand and lifting, repeated 3 times. 3D angular kinematics were calculated for each spine segment. Segmental redundancy was evaluated through cross-correlation (Rxy) analysis of kinematics time series and correlation of range of motion (RROM) of adjacent spine segments.Results: The upper/lower lumbar pairing showed weak correlations in the LBP group for all tasks and anatomical planes (Rxyrange:0.02–0.36) but moderate and strong correlations during walking (Rxy _frontalplane:0.4) and lifting (Rxy _sagittalplane:0.64) in the healthy group. The lower thoracic/upper lumbar pairing had weak correlations for both groups during lifting and sit-to-stand in the frontal plane and for walking (Rxy:0.01) in the sagittal plane only. The upper/lower thoracic pairing had moderate correlations during sit-to-stand in sagittal and transverse plane in patients with LBP (Rxy _sagittalplane:0.41; Rxy _transverse plane:−0.42) but weak in healthy (Rxy _sagittalplane:0.23; Rxy _transverseplane:−0.34); the contrary was observed during lifting.The majority of RROM values (55/72) demonstrated weak correlations.Significance:The results suggest that multi-segmental analysis of the spine is necessary if spine movement characteristics are to be

  • Journal article
    Bhattacharyya R, Davidson DJ, Sugand K, Akhbari P, Bartlett MJ, Bhattacharya R, Gupte CMet al., 2018,

    Knee Arthroscopy: A Simulation Demonstrating the Imperial Knee Arthroscopy Cognitive Task Analysis (IKACTA) Tool.

    , JBJS Essent Surg Tech, Vol: 8, Pages: e32-e32, ISSN: 2160-2204

    Background: Virtual reality and cadaveric simulations are expensive and not readily accessible1. Innovative and accessible training adjuncts are required to help meet training needs. Cognitive task analysis (CTA) has been used extensively to train pilots and surgeons in other surgical specialties2-6. However, the use of CTA tools within orthopaedics is in its infancy. Arthroscopic procedures are minimally invasive and require a different skill set compared with open surgery. Residents often feel poorly prepared to perform this in the operating room because of the steep learning curve associated with acquiring basic arthroscopic skills. We designed the Imperial Knee Arthroscopy Cognitive Task Analysis (IKACTA) tool, which is, to our knowledge, the first CTA tool described in the orthopaedic literature, demonstrating significant objective benefits in training novices to perform diagnostic knee arthroscopy. Description: The IKACTA tool, which is the combination of the written description of the phases below and the videos (with superimposed audio recordings) of each phase, utilizes simultaneous written and audiovisual modalities to teach diagnostic knee arthroscopy. The procedure was divided into 7 phases: (1) operating room and patient setup, (2) preparation and draping, (3) anterolateral portal placement, (4) examination of the patellofemoral joint and the lateral gutter, (5) examination of the medial compartment and anteromedial portal placement, (6) examination of the intercondylar notch and the lateral compartment, and (7) postoperative care and rehabilitation.For each phase, there are sections on the technical steps, cognitive decision-making behind each technical step, and potential errors and solutions. Video clips recorded by an expert surgeon in the operating room specific to each phase and audio voice recordings explaining each phase superimposed on the video clips were combined with the written information to design the IKACTA tool. Alternatives: Not applic

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