BBSRC funding will help to establish the next generation of poultry virologists in the UK.
Based on a news release from the Biotechnology and Biological Sciences Research Council
Over £6.2 million of Biotechnology and Biological Sciences Research Council (BBSRC) funding has been awarded to develop rapid responses to emerging poultry viruses. The funding boost will also help to establish the next generation of poultry virologists, to work in a scientific area where the UK has traditionally been strong.
The ‘Developing Rapid Responses to Emerging Virus Infections of Poultry’ project will enable the recognition of emerging viruses before widespread infections occur, prepare for the possibility of new subtypes of avian influenza, and help the process of developing better vaccines for poultry and humans.
The research will be led by Dr Michael Skinner, from the Department of Medicine at Imperial College London. It will involve close collaboration with Professor Wendy Barclay (also at Imperial); Dr Laurence Tiley, Professor Jim Kaufman and Professor Ian Goodfellow (all at the University of Cambridge); Professor Steve Goodbourn (St George's, University of London); Professor Venugopal Nair (of The Pirbright Institute and a visiting professor at Imperial College London); and Professor Helen Sang at the University of Edinburgh’s The Roslin Institute.
This research will address important scientific challenges to allow better isolation and diagnosis of emerging viruses, as well as faster and better production of vaccines against them. Scientists will study endemic and exotic viruses, in an era when new poultry viruses rapidly cross national and continental boundaries to become global problems.
Dr Michael Skinner said: “One area of the research will help us to identify infections early. We are looking for distinct signatures that appear upon infection of cells in the lab. We can use these signatures to create means of detecting new viruses, especially in elite breeder flocks, where the UK and Europe has an important global commercial presence”.
Poultry virus research is vital, not only for the protection of an important source of animal protein to feed a growing world population, but also for human health. Poultry virus research enabled the development of the influenza vaccine and the use of interferons as antiviral medicine.
Dr Skinner added: “The study of poultry viruses has made an important contribution to the development of the modern science of virology. We also need to understand the way viruses interact with chicken cells because isolation and diagnosis of viruses is often conducted in eggs or avian cells and some important human vaccines, including those for seasonal and pandemic influenza, are produced in them”.
In addition to boosting knowledge, the funding will increase effort in poultry virology in anticipation of new facilities at The Pirbright Institute and the multi-million pound National Avian Research Facility, which is a collaboration between the Roslin Institute and The Pirbright Institute.
Professor Venugopal Nair said: “This funding will help secure effective capacity and closer working between the UK academic institutions, in advance of the commissioning of new world-class facilities, to enable the study of the world's most devastating poultry viruses.”
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