Feb 2015 - Article in Chem. Comm. Published

Chem. Comm. Cover

Laurence's paper on Mn-Salen Catalysed Benzylic C-H Activation for the Synthesis of Aryl [18F]CF3-containing PET probes published.

L.S.Carroll, H.L. Evans, A.C. Spivey and E.O. Aboagye 'Mn-Salen Catalysed Benzylic C-H Activation for the Synthesis of Aryl{18F]CF3-Containing PET Probes, Chem. Comm. 2015, ASAP, DOI: 10.1039/C4CC05762G

The development of a Mn-salen complex catalysed oxidative benzylic fluorination of non-activated C-H bonds using [18F]fluoride is described for installation of [18F]CHRF, [18F]CR2F and particularly [18F]CF3 containing groups in the presence of other functional groups.