Currently recruiting studies

Short summary:

The study will investigate if and how alpha-MSH (a natural hormone) can reduce blood sugar levels. This could potentially lead to new treatments for type 1 diabetes.

Full summary:

Currently recruiting female participants with type 1 diabetes

Participants will be required to attend the Imperial Clinical Research Facility for screening and two 4-hour study visits. They will receive alpha MSH or placebo, have blood samples taken and two small (size of rice grain) muscle biopsies taken from your leg.  The hormone infusion is safe, with only redness of the face reported by some people.

Participants will be reimbursed £200 for their time and travel costs.

For more information, contact brett.johnson@nhs.net

Short summary:

We are looking for volunteers over the age of 18 and without a formal diagnosis of an existing memory problem or medical condition that may impact memory later in life to perform an online memory test.

Full summary:

You are invited to take part in this study if you are over 18 years of age and without a formal diagnosis of an existing memory problem, or a medical condition that may have an influence on memory later in life.

‘Chemobrain’ is a common but poorly understood side effect of chemotherapy for many cancer patients. The term is used to describe a collection of signs and symptoms including difficulties with concentration, multi-tasking, recalling words/conversations and confusion. Chemobrain occurs in approximately 50% of cancer patients undergoing chemotherapy. Whilst some patients recover, many are left with permanent memory problems affecting their quality of life. Studies of women with breast cancer have shown that chemotherapy may cause changes within the brain. However, the processes at play that are causing these changes are unclear. Breast cancer patients recruited to the Chemobrain study have been invited to complete 3-monthly online memory tests for up to 12 months. In order to quantify these cognitive changes effectively, it is very important for us to compare the scores generated by our breast cancer patients with those produced by a healthy control group.

If you were interested to participate in our CHEMOBRAIN sub-study for volunteers, we would invite you to complete a set of memory tests. These will take approximately 45-60 minutes to complete. Each test has clear instructions, with video demonstrations and practice rounds. The tests are designed to assess an array of cognitive abilities including recall, executive function, verbal fluency, memory, concentration, and global cognitive function. The tests are most compatible with a tablet or PC. Following completion of the online memory test, we may invite you to come to Hammersmith for an optional in-person memory assessment and blood sample collection. The research team will discuss all of the procedures with you and answer any questions you may have. If you are interest in learning more about this study, please contact chemobrain@imperial.ac.uk.

Short summary:

We are searching to understand what are the mechanisms that lead to a disorder named Parkinson’s disease, for which there is no therapy so far that could change its course. 

Full summary:

We are searching to understand the role of some of the potential mechanisms by which Parkinson’s disease develops in the hope that this could help in designing more effective therapies that could slow down the course of the disease.  

We are looking for patients with a diagnosis of Parkinson’s disease, patients carrying mutations to gene that predispose for Parkinson’s disease, and healthy volunteers.  

This study programme is structured of two different protocols, involving a clinical visit, some scans (pictures of the brain) named PET, MRI and SPECT scans, which help understand what the function of specific molecules of the brain is, and a lumbar puncture which is optional.  

According to the study protocol, your involvement to the study would involve between four and eight visits over a time span of approximately one year. Travel and, if needed, accommodation for you and one companion will be provided, and you will be paid a contribution for attending study visits should you enrol. 

For more information, contact neuro@exeter.ac.uk 

Short summary:

The study is looking at the effects of the diabetes and weight loss drug, semaglutide, on blood sugar levels when people are given anti-inflammatory steroids (such as dexamethasone).

Full summary:

Short summary:

We are investigating the motivational processes underlying self-harm in young people (aged 16-25). iMAGine Part 4 is a continuation of Part 3 with a specific focus on comparing non-autistic to autistic people.

Full summary:

Who can take part?

• Young people aged 16-25
• Experience of self-harm within the last year
• Both autistic and non-autistic people

What is the study about?

In iMAGine Part 3, we focused on comparing motivational differences between young people who self-harm and young people who do not have a history of mental health difficulties. iMAGine Part 4 has a specific focus on neurodiverse individuals where we are comparing the motivational processes underlying self-harm between autistic and non-autistic young people.

What does the study involve?

Participants undergo an online and telephone screening followed by an in-person visit. At the study visit, participants are asked to complete questionnaires related to their self-harm, experiences and mental health followed by 4 tasks. 3 of the tasks are computer-based and the 4th task is an imagery task where we try to modify mental images related to self-harm.

Participants will be reimbursed £50 for their time.

What can I do if I’m interested in taking part?

For more information, contact imagine@imperial.ac.uk

Or visit our:

• Website: www.imaginestudy.org
• Instagram page: @mir_imperial

Short summary:

We are looking for men or women who are currently using or previously used anabolic steroids to understand what happens to hormone levels and symptoms

Full summary:

When men or women stop taking anabolic steroids (also known as ‘steroids’) they may experience symptoms of low hormone levels. We do not know how long men and women experience these symptoms for or how severe these symptoms can be. We want to try and answer these questions which can be used to develop future treatments. 

We are looking for men and women aged 18 – 60 years old who are currently using or have used anabolic steroids within in the last 1 year. 

The study involves one appointment approximately 30 minutes long where you will complete a detailed questionnaire, have a blood test and provide a urine sample. We will provide you with a copy of your blood results after the appointment with an explanation of the results. You will be reimbursed travel expenses depending on distance travelled. 

For more information, contact anst01@ic.ac.uk