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• Journal article
  Schievano S, Sebire NJ, Robertson NJ, Taylor AM, Thayyil Set al., 2010,

  Reconstruction of fetal and infant anatomy using rapid prototyping of post-mortem MR images.

  , Insights Imaging, Vol: 1, Pages: 281-286, ISSN: 1869-4101

  OBJECTIVES: The recent decline in autopsy rates and lack of human anatomical material donated for research and training has resulted in issues for medical training in the United Kingdom. This study aims to examine the feasibility of making accurate three-dimensional (3D) models of the human body and visceral organs using post-mortem magnetic resonance (MR) imaging and rapid prototyping. METHODS: We performed post-mortem MR imaging using a 3D T2-weighted sequence in 11 fetuses and infants, before autopsy, using either a 1.5-T or 9.4-T MR scanner. Internal organs were reconstructed in silico and 3D models were created by rapid prototyping. RESULTS: The median gestation of fetuses was 20 (range 19-30) weeks and the median age of infants was 12 (range 8-16) weeks. Models created by rapid prototyping accurately depicted structural abnormalities and allowed clear visualisation of 3D relationships. CONCLUSIONS: Accurate 3D modelling of anatomical features from post-mortem imaging in fetuses and infants is feasible. These models could have a large number of medical applications, including improved parental counselling, invaluable teaching resources and significant medico-legal applications to demonstrate disease or injury, without the need to show actual autopsy photographs.

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• Journal article
  Thayyil S, Chitty LS, Robertson NJ, Taylor AM, Sebire NJet al., 2010,

  Minimally invasive fetal postmortem examination using magnetic resonance imaging and computerised tomography: current evidence and practical issues

  , PRENATAL DIAGNOSIS, Vol: 30, Pages: 713-718, ISSN: 0197-3851
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  • Citations: 50
• Journal article
  Thayyil S, Chandrasekaran M, Chitty LS, Wade A, Skordis-Worrall J, Bennett-Britton I, Cohen M, Withby E, Sebire NJ, Robertson NJ, Taylor AMet al., 2010,

  Diagnostic accuracy of post-mortem magnetic resonance imaging in fetuses, children and adults: A systematic review

  , EUROPEAN JOURNAL OF RADIOLOGY, Vol: 75, Pages: E142-E148, ISSN: 0720-048X
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  • Citations: 54
• Journal article
  Thayyil S, Bhutta ZA, Ramji S, Costello AM, Robertson NJet al., 2010,

  Global application of therapeutic hypothermia to treat perinatal asphyxial encephalopathy

  , INTERNATIONAL HEALTH, Vol: 2, Pages: 79-81, ISSN: 1876-3413
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  • Citations: 4
• Journal article
  Thayyil S, Robertson NJ, 2010,

  University College London (UCL) Symposia on Neonatal Neurology and Neuro Protection

  , INDIAN PEDIATRICS, Vol: 47, Pages: 395-395, ISSN: 0019-6061
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• Journal article
  Thayyil S, Chandrasekaran M, Taylor A, Bainbridge A, Cady EB, Chong WKK, Murad S, Omar RZ, Robertson NJet al., 2010,

  Cerebral Magnetic Resonance Biomarkers in Neonatal Encephalopathy: A Meta-analysis

  , PEDIATRICS, Vol: 125, Pages: E382-E395, ISSN: 0031-4005
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  • Citations: 258
• Journal article
  Thayyil S, Cleary JO, Sebire NJ, Scott RJ, Chong K, Gunny R, Owens CM, Olsen OE, Offiah AC, Parks HG, Chitty LS, Price AN, Yousry TA, Robertson NJ, Lythgoe MF, Taylor AMet al., 2009,

  Postmortem Examination of Human Fetuses: A Comparison of Whole-Body High-Field MRI at 9.4 Tesla With Conventional MRI and Invasive Autopsy EDITORIAL COMMENT

  , OBSTETRICAL & GYNECOLOGICAL SURVEY, Vol: 64, Pages: 787-789, ISSN: 0029-7828
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• Journal article
  Thayyil S, Schievano S, Robertson NJ, Jones R, Chitty LS, Sebire NJ, Taylor AMet al., 2009,

  A semi-automated method for non-invasive internal organ weight estimation by post-mortem magnetic resonance imaging in fetuses, newborns and children

  , EUROPEAN JOURNAL OF RADIOLOGY, Vol: 72, Pages: 321-326, ISSN: 0720-048X
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  • Citations: 31
• Journal article
  Thayyil S, Cleary JO, Sebire NJ, Scott RJ, Chong K, Gunny R, Owens CM, Olsen OE, Offiah AC, Parks HG, Chitty LS, Price AN, Yousry TA, Robertson NJ, Lythgoe MF, Taylor AMet al., 2009,

  Post-mortem examination of human fetuses: a comparison of whole-body high-field MRI at 9.4 T with conventional MRI and invasive autopsy

  , LANCET, Vol: 374, Pages: 467-475, ISSN: 0140-6736
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  • Citations: 100
• Journal article
  Thayyil S, Robertson NJ, Scales A, Weber MA, Jacques TS, Sebire NJ, Taylor AMet al., 2009,

  Prospective parental consent for autopsy research following sudden unexpected childhood deaths: a successful model

  , ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 94, Pages: 354-358, ISSN: 0003-9888
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  • Citations: 22

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